MX2020000352A - Marcador radioactivo de modo dual y terapeuticos. - Google Patents

Marcador radioactivo de modo dual y terapeuticos.

Info

Publication number
MX2020000352A
MX2020000352A MX2020000352A MX2020000352A MX2020000352A MX 2020000352 A MX2020000352 A MX 2020000352A MX 2020000352 A MX2020000352 A MX 2020000352A MX 2020000352 A MX2020000352 A MX 2020000352A MX 2020000352 A MX2020000352 A MX 2020000352A
Authority
MX
Mexico
Prior art keywords
radiotracer
therapeutics
dual mode
sifa
silicon
Prior art date
Application number
MX2020000352A
Other languages
English (en)
Spanish (es)
Inventor
Alexander Josef Wurzer
Hans-Jürgen Wester
Matthias Johannes Eiber
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Publication of MX2020000352A publication Critical patent/MX2020000352A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
MX2020000352A 2017-07-28 2018-07-30 Marcador radioactivo de modo dual y terapeuticos. MX2020000352A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17183795 2017-07-28
PCT/EP2018/070533 WO2019020831A1 (en) 2017-07-28 2018-07-30 AGENTS WITH TWO RADIOTRATIVE AND THERAPEUTIC MODES

Publications (1)

Publication Number Publication Date
MX2020000352A true MX2020000352A (es) 2020-08-17

Family

ID=59501286

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020000352A MX2020000352A (es) 2017-07-28 2018-07-30 Marcador radioactivo de modo dual y terapeuticos.
MX2023007914A MX2023007914A (es) 2017-07-28 2020-01-10 Marcador radioactivo de modo dual y terapeuticos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023007914A MX2023007914A (es) 2017-07-28 2020-01-10 Marcador radioactivo de modo dual y terapeuticos.

Country Status (21)

Country Link
US (4) US11413360B2 (https=)
EP (3) EP4000640A1 (https=)
JP (2) JP7059372B2 (https=)
KR (2) KR102752620B1 (https=)
CN (1) CN111132700B (https=)
AU (2) AU2018308699B2 (https=)
BR (1) BR112020001785A2 (https=)
CA (1) CA3071315A1 (https=)
DK (1) DK3658194T3 (https=)
EA (1) EA202090370A1 (https=)
ES (1) ES3011272T3 (https=)
FI (1) FI3658194T3 (https=)
HU (1) HUE070098T2 (https=)
IL (2) IL318092A (https=)
MX (2) MX2020000352A (https=)
NZ (1) NZ760537A (https=)
PL (1) PL3658194T3 (https=)
PT (1) PT3658194T (https=)
SG (1) SG11202000725WA (https=)
WO (1) WO2019020831A1 (https=)
ZA (1) ZA202000467B (https=)

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EA202090370A1 (ru) 2017-07-28 2020-05-25 Технише Универзитет Мюнхен Двухрежимная радиоактивная метка и радиотерапевтическое средство
IL303420A (en) * 2019-01-30 2023-08-01 Univ Muenchen Tech Diagnostic imaging materials for cancer
CN113677375B (zh) * 2019-01-30 2024-07-23 慕尼黑工业大学 氟化硅受体取代的放射性药物及其前体
EP3917626B1 (en) * 2019-01-30 2023-05-31 Technische Universität München Psma binding dual mode radiotracer and therapeutic
CN112168978B (zh) * 2019-07-03 2022-01-11 北京大学 一种抗体偶联药物及其药物组合物与应用
WO2021086917A1 (en) * 2019-10-29 2021-05-06 The Cleveland Clinic Foundation Psma-targeting imaging agents
CN113350531A (zh) * 2020-03-02 2021-09-07 上海核力星医药科技有限公司 前列腺特异性膜抗原结合配体偶联物及其应用
GB202005282D0 (en) * 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations
WO2022018264A1 (en) 2020-07-23 2022-01-27 Technische Universität München Silicon-containing ligand compounds
CN116583527A (zh) 2020-09-03 2023-08-11 库瑞姆美国有限责任公司 用于64Cu-DOTATATE放大规模的放射性标记和制剂
EP4023250A1 (en) * 2021-01-04 2022-07-06 Technische Universität München Dual mode radiotracer and -therapeutics
US20240165281A1 (en) 2021-02-15 2024-05-23 Technische Universität München Dual mode radiotracer and therapeutics
US20240181092A1 (en) * 2021-04-02 2024-06-06 Novartis Ag Diagnostic methods of prostate cancer
KR20240008341A (ko) * 2021-05-14 2024-01-18 테크니쉐 유니베르시테트 뮌헨 방사성약제학적 소마토스타틴 수용체 리간드 및 그의 전구체
GB202108779D0 (en) 2021-06-18 2021-08-04 Blue Earth Diagnostics Ltd Si-at therapeutic/diagnostic compounds
GB202109922D0 (en) 2021-07-09 2021-08-25 Blue Earth Diagnostics Ltd Radiotracers and therapeutics binding to fibroblast activation protein (fap)
IL310066A (en) * 2021-08-05 2024-03-01 Technische Universit?T M?Nchen Ligand compounds comprising a chelating group as a bridging group
GB202113646D0 (en) 2021-09-24 2021-11-10 Blue Earth Diagnostics Ltd Method of preparation of 18F labelled silyl-fluoride compounds
CN114671806B (zh) * 2022-04-08 2024-03-01 上海如絮生物科技有限公司 一种亲水性吡啶衍生物、中间体、其制备方法及应用
GB202207372D0 (en) 2022-05-19 2022-07-06 Blue Earth Diagnostics Ltd Synthesis of fluorosilyl compounds
CA3257852A1 (en) 2022-07-29 2024-02-01 Technische Universitat Munchen Silicon Fluoride Accepting Groups for Radiopharmaceutical Products
WO2024054226A1 (en) * 2022-09-06 2024-03-14 Hoang Ba Xuan Gallium nitrate and dimethyl sulfoxide composition for respiratory treatment
JP2025532619A (ja) * 2022-09-20 2025-10-01 テクニシェ ユニバーシタット ミュンヘン イメージングおよび標的化放射線治療のための新規ミニガストリン由来コレシストキニン2受容体結合分子
AU2023347470A1 (en) 2022-09-23 2025-04-10 Nuclidium Ag High-purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof
TW202426433A (zh) 2022-09-23 2024-07-01 瑞士商紐利迪姆股份公司 成纖維細胞活化蛋白(fap)抑制劑、fap結合物及其診斷與治療用途
AU2023379454A1 (en) * 2022-11-14 2025-05-29 Aktis Oncology, Inc. Decreased retention of miniproteins in kidney
TW202530249A (zh) 2023-09-29 2025-08-01 美商雅克提斯腫瘤學公司 小蛋白、結合物及其用途
GB202316239D0 (en) 2023-10-24 2023-12-06 Blue Earth Diagnostics Ltd Therapeutic combination
WO2025250644A1 (en) * 2024-05-28 2025-12-04 Case Western Reserve University Fluorescent nuclide-containing agents for detecting and treating cancer

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AU7384394A (en) * 1993-06-30 1995-01-24 Akzo Nobel N.V. Chelating compounds
WO2003011345A1 (en) 2001-07-27 2003-02-13 Targesome, Inc. Lipid constructs as therapeutic and imaging agents
CN102626522B (zh) * 2012-04-12 2014-09-10 韩彦江 基于趋化因子受体cxcr4多肽类拮抗剂的多肽放射性诊断与治疗药物
CN106794264B (zh) * 2014-06-10 2021-03-23 3B制药有限公司 包含神经降压肽受体配体的缀合物及其用途
EP3209336B1 (en) 2014-10-20 2019-12-11 Deutsches Krebsforschungszentrum 18f-tagged inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
US20160287730A1 (en) * 2015-03-31 2016-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv Labeled evans blue dye derivative for in vivo serum albumin labeling
CN107667109B (zh) * 2015-05-26 2021-08-03 加利福尼亚大学董事会 可用于分子和生物分子的18f标记的新的杂芳族硅-氟化物-受体及其制备方法
EA202090370A1 (ru) 2017-07-28 2020-05-25 Технише Универзитет Мюнхен Двухрежимная радиоактивная метка и радиотерапевтическое средство
BR112020011727A2 (pt) * 2017-12-11 2020-11-17 Technische Universität München ligantes de psma para imageamento e endorradioterapia
IL303420A (en) 2019-01-30 2023-08-01 Univ Muenchen Tech Diagnostic imaging materials for cancer
EP3917626B1 (en) 2019-01-30 2023-05-31 Technische Universität München Psma binding dual mode radiotracer and therapeutic

Also Published As

Publication number Publication date
NZ760537A (en) 2026-01-30
KR20240027896A (ko) 2024-03-04
US11413360B2 (en) 2022-08-16
JP2022101601A (ja) 2022-07-06
JP7059372B2 (ja) 2022-04-25
CA3071315A1 (en) 2019-01-31
EP3658194B1 (en) 2024-11-27
EP4424378A2 (en) 2024-09-04
AU2018308699A1 (en) 2020-01-23
EP3658194A1 (en) 2020-06-03
US12453787B2 (en) 2025-10-28
FI3658194T3 (fi) 2025-02-28
JP2020528461A (ja) 2020-09-24
US20260021211A1 (en) 2026-01-22
KR102752620B1 (ko) 2025-01-10
PL3658194T3 (pl) 2025-09-15
DK3658194T3 (da) 2025-02-17
WO2019020831A1 (en) 2019-01-31
IL318092A (en) 2025-02-01
ES3011272T3 (en) 2025-04-07
IL272291B1 (en) 2025-02-01
US12390540B2 (en) 2025-08-19
US20200197545A1 (en) 2020-06-25
AU2018308699B2 (en) 2023-11-30
MX2023007914A (es) 2023-07-13
IL272291A (en) 2020-03-31
CN111132700B (zh) 2022-12-13
US20220370649A1 (en) 2022-11-24
HUE070098T2 (hu) 2025-05-28
KR20200064057A (ko) 2020-06-05
BR112020001785A2 (pt) 2020-09-29
ZA202000467B (en) 2022-06-29
EA202090370A1 (ru) 2020-05-25
AU2024200440B2 (en) 2025-04-24
PT3658194T (pt) 2025-02-13
IL272291B2 (en) 2025-06-01
SG11202000725WA (en) 2020-02-27
CN111132700A (zh) 2020-05-08
EP4424378A3 (en) 2024-12-11
EP4000640A1 (en) 2022-05-25
US20250121102A1 (en) 2025-04-17
AU2024200440A1 (en) 2024-02-08

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