MX2019012534A - Combinacion de elafibranor o derivados del mismo con un agente anti-ehna, antifibrotico o anticolestasico. - Google Patents
Combinacion de elafibranor o derivados del mismo con un agente anti-ehna, antifibrotico o anticolestasico.Info
- Publication number
- MX2019012534A MX2019012534A MX2019012534A MX2019012534A MX2019012534A MX 2019012534 A MX2019012534 A MX 2019012534A MX 2019012534 A MX2019012534 A MX 2019012534A MX 2019012534 A MX2019012534 A MX 2019012534A MX 2019012534 A MX2019012534 A MX 2019012534A
- Authority
- MX
- Mexico
- Prior art keywords
- elafibranor
- nash
- fibrotic
- derivatives
- combination
- Prior art date
Links
- 230000002202 anti-cholestatic effect Effects 0.000 title 1
- 230000003510 anti-fibrotic effect Effects 0.000 title 1
- 229950001279 elafibranor Drugs 0.000 title 1
- AFLFKFHDSCQHOL-IZZDOVSWSA-N gft505 Chemical compound C1=CC(SC)=CC=C1C(=O)\C=C\C1=CC(C)=C(OC(C)(C)C(O)=O)C(C)=C1 AFLFKFHDSCQHOL-IZZDOVSWSA-N 0.000 title 1
- 239000013066 combination product Substances 0.000 abstract 1
- 229940127555 combination product Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se refiere a un producto de combinación y a su uso en terapia.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17305452 | 2017-04-18 | ||
EP18305150 | 2018-02-13 | ||
PCT/EP2018/059967 WO2018193006A1 (en) | 2017-04-18 | 2018-04-18 | Combination of elafibranor or derivatives thereof with an anti-nash, anti-fibrotic or anti-cholestatic agent |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019012534A true MX2019012534A (es) | 2020-08-17 |
Family
ID=61972154
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012535A MX2019012535A (es) | 2017-04-18 | 2018-04-18 | Combinacion que comprende un agonista de ppar tal como elafibranor y un inhibidor de la acetil-coa carboxilasa (acc). |
MX2019012534A MX2019012534A (es) | 2017-04-18 | 2018-04-18 | Combinacion de elafibranor o derivados del mismo con un agente anti-ehna, antifibrotico o anticolestasico. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012535A MX2019012535A (es) | 2017-04-18 | 2018-04-18 | Combinacion que comprende un agonista de ppar tal como elafibranor y un inhibidor de la acetil-coa carboxilasa (acc). |
Country Status (12)
Country | Link |
---|---|
US (2) | US11484517B2 (es) |
EP (2) | EP3612176A1 (es) |
JP (2) | JP7266530B2 (es) |
CN (2) | CN110536683A (es) |
AU (2) | AU2018254743B2 (es) |
BR (2) | BR112019021914A2 (es) |
CA (2) | CA3057940A1 (es) |
IL (1) | IL269829B (es) |
MX (2) | MX2019012535A (es) |
PH (1) | PH12019502348A1 (es) |
SG (1) | SG11201909168VA (es) |
WO (2) | WO2018193007A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
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CA2606499C (en) | 2005-05-26 | 2017-06-13 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
EA201891154A1 (ru) | 2011-10-28 | 2019-02-28 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
SG11201707276PA (en) | 2015-03-09 | 2017-10-30 | Intekrin Therapeutics Inc | Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy |
US12053445B2 (en) * | 2016-03-31 | 2024-08-06 | Genfit | Methods of treatment of cholestatic diseases |
MX2019005730A (es) | 2016-11-21 | 2019-10-21 | Viking Therapeutics Inc | Metodo para tratar enfermedad de almacenamiento de glucogeno. |
AU2018249822A1 (en) | 2017-04-03 | 2019-10-31 | Coherus Biosciences Inc. | PPArgamma agonist for treatment of progressive supranuclear palsy |
SG11201909168VA (en) * | 2017-04-18 | 2019-11-28 | Genfit | Combination comprising a ppar agonist such as elafibranor and an acetyl-coa carboxylase (acc) inhibitor |
CN110996966A (zh) | 2017-06-05 | 2020-04-10 | 维京治疗公司 | 用于治疗纤维化的组合物 |
AU2018326785B2 (en) | 2017-09-03 | 2023-03-02 | Angion Biomedica Corp. | Vinylheterocycles as Rho-associated coiled-coil kinase (ROCK) inhibitors |
KR102419458B1 (ko) | 2017-10-06 | 2022-07-12 | 길리애드 사이언시즈, 인코포레이티드 | Acc 억제제를 포함하는 조합 요법 |
JP2022510690A (ja) * | 2018-12-05 | 2022-01-27 | バイキング・セラピューティクス・インコーポレイテッド | 肝障害の処置のための組成物及び方法 |
JP2022510691A (ja) * | 2018-12-05 | 2022-01-27 | バイキング・セラピューティクス・インコーポレイテッド | 線維症及び炎症の処置のための組成物 |
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AU2018253885B2 (en) | 2024-04-11 |
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AU2018254743B2 (en) | 2024-04-11 |
WO2018193007A1 (en) | 2018-10-25 |
JP2020517621A (ja) | 2020-06-18 |
IL269829A (en) | 2019-11-28 |
BR112019021910A2 (pt) | 2020-05-26 |
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IL269829B (en) | 2022-05-01 |
SG11201909168VA (en) | 2019-11-28 |
MX2019012535A (es) | 2020-08-17 |
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