MX2019010101A - Composiciones y metodos para promover el crecimiento del cabello con inhibidores de mpc1. - Google Patents

Composiciones y metodos para promover el crecimiento del cabello con inhibidores de mpc1.

Info

Publication number
MX2019010101A
MX2019010101A MX2019010101A MX2019010101A MX2019010101A MX 2019010101 A MX2019010101 A MX 2019010101A MX 2019010101 A MX2019010101 A MX 2019010101A MX 2019010101 A MX2019010101 A MX 2019010101A MX 2019010101 A MX2019010101 A MX 2019010101A
Authority
MX
Mexico
Prior art keywords
compositions
methods
hair growth
promoting hair
mpc1
Prior art date
Application number
MX2019010101A
Other languages
English (en)
Inventor
e lowry William
CHRISTOFK Heather
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Priority claimed from PCT/US2017/048701 external-priority patent/WO2018039612A1/en
Publication of MX2019010101A publication Critical patent/MX2019010101A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

En la presente se proporcionan métodos para acelerar, promover o restaurar el crecimiento del cabello, que comprenden administrarle a un sujeto que lo necesite una cantidad eficaz de un compuesto de la fórmula (I). También se proporcionan composiciones que comprenden el compuesto de la fórmula (I).
MX2019010101A 2017-02-24 2017-08-25 Composiciones y metodos para promover el crecimiento del cabello con inhibidores de mpc1. MX2019010101A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762463232P 2017-02-24 2017-02-24
PCT/US2017/048701 WO2018039612A1 (en) 2016-08-26 2017-08-25 Compositions and methods for promoting hair growth with mpc1 inhibitors

Publications (1)

Publication Number Publication Date
MX2019010101A true MX2019010101A (es) 2019-10-15

Family

ID=67297690

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019010101A MX2019010101A (es) 2017-02-24 2017-08-25 Composiciones y metodos para promover el crecimiento del cabello con inhibidores de mpc1.

Country Status (13)

Country Link
US (1) US11213513B2 (es)
EP (1) EP3585381A4 (es)
JP (1) JP7046086B2 (es)
KR (1) KR102440809B1 (es)
CN (1) CN110300583A (es)
AU (1) AU2017314833A1 (es)
BR (1) BR112019015552A2 (es)
CA (1) CA3050635A1 (es)
EA (1) EA038943B1 (es)
IL (1) IL268345B (es)
MX (1) MX2019010101A (es)
PE (1) PE20200600A1 (es)
SG (1) SG11201906807VA (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201906807VA (en) 2017-02-24 2019-08-27 Univ California Compositions and methods for promoting hair growth with mpc1 inhibitors
US11534383B2 (en) 2017-06-26 2022-12-27 Virtue Labs, LLC Cosmetic compositions and methods of use
CA3067746A1 (en) 2017-06-30 2019-01-03 The Regents Of The University Of California Compositions and methods for modulating hair growth
KR20240007905A (ko) * 2021-04-14 2024-01-17 버츄 랩스 엘엘씨 모발 처리 조성물 및 사용 방법
EP4384167A1 (en) * 2021-08-13 2024-06-19 Mpc Therapeutics Sa [1,2,4]triazolo[4,3-a]pyrimidin-7(8h)-one as mitochondrial pyruvate carrier inhibitors for use in the treatment of cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9014221D0 (en) 1990-06-26 1990-08-15 Janssen Pharmaceutica Nv Method of treating alopecia
GB9023585D0 (en) 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
FR2796274B1 (fr) * 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
AU2001239826B2 (en) 2000-02-23 2006-06-15 Orentreich Foundation For The Advancement Of Science, Inc. Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus
EP1605967A1 (en) 2003-03-13 2005-12-21 Novo Nordisk A/S Novel nph insulin preparations
KR20160028498A (ko) * 2004-09-24 2016-03-11 메소블라스트, 아이엔씨. 간엽 전구세포의 증식 및/또는 생존성 증강 방법
AU2006339311A1 (en) 2005-06-07 2007-09-07 Foamix Ltd. Antibiotic kit and composition and uses thereof
JP2007191473A (ja) * 2005-12-21 2007-08-02 Daiichi Sankyo Healthcare Co Ltd 新規な育毛用組成物
US8563500B2 (en) 2007-09-05 2013-10-22 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Methods and compounds for treating diseases caused by reactive oxygen species
CN104125956B (zh) 2011-12-22 2019-08-16 康内克斯生命科学私人有限公司 作为11-β-羟基类固醇脱氢酶的抑制剂的环酰胺及其用途
JP5956242B2 (ja) * 2012-05-09 2016-07-27 富士産業株式会社 まつ毛・眉毛用の育毛用組成物
US20150099790A1 (en) * 2012-05-10 2015-04-09 University Of Utah Research Foundation Compositions and methods for modulating mitochondrial pyruvate carrier activity
WO2014207213A1 (en) 2013-06-28 2014-12-31 Medizinische Universität Innsbruck Novel inhibitors of protein kinase c epsilon signaling
US20160250249A1 (en) * 2013-10-03 2016-09-01 Inserm ( Institute National De Lasanté Et De La Re Cherche Médicale) Methods and pharmaceutical compositions for modulating autophagy in a subject in need thereof
US9636340B2 (en) 2013-11-12 2017-05-02 Ayyappan K. Rajasekaran Kinase inhibitors
WO2018039612A1 (en) 2016-08-26 2018-03-01 The Regents Of The University Of California Compositions and methods for promoting hair growth with mpc1 inhibitors
SG11201906807VA (en) 2017-02-24 2019-08-27 Univ California Compositions and methods for promoting hair growth with mpc1 inhibitors
CN106880693A (zh) 2017-03-22 2017-06-23 广州国草夏方生物科技有限公司 一种治疗脂溢性脱发的生发液组合物及其制备方法
CA3067746A1 (en) 2017-06-30 2019-01-03 The Regents Of The University Of California Compositions and methods for modulating hair growth
SG10202109849SA (en) 2017-09-29 2021-10-28 Univ California Compositions and methods for modulating hair growth
CN113631555A (zh) 2019-01-02 2021-11-09 加利福尼亚大学董事会 用于调节毛发生长的组合物和方法

Also Published As

Publication number Publication date
CA3050635A1 (en) 2018-03-01
EP3585381A1 (en) 2020-01-01
EA201991988A1 (ru) 2020-01-24
AU2017314833A1 (en) 2019-07-25
KR102440809B1 (ko) 2022-09-05
KR20190119118A (ko) 2019-10-21
IL268345A (en) 2019-09-26
US20200030289A1 (en) 2020-01-30
IL268345B (en) 2022-08-01
EP3585381A4 (en) 2020-08-19
BR112019015552A2 (pt) 2020-03-17
EA038943B1 (ru) 2021-11-12
JP7046086B2 (ja) 2022-04-01
SG11201906807VA (en) 2019-08-27
PE20200600A1 (es) 2020-03-10
JP2020524127A (ja) 2020-08-13
US11213513B2 (en) 2022-01-04
CN110300583A (zh) 2019-10-01

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