MX2018015469A - Una vacuna de rotavirus sin tampón, de volumen de dosis bajo y estable al ácido. - Google Patents
Una vacuna de rotavirus sin tampón, de volumen de dosis bajo y estable al ácido.Info
- Publication number
- MX2018015469A MX2018015469A MX2018015469A MX2018015469A MX2018015469A MX 2018015469 A MX2018015469 A MX 2018015469A MX 2018015469 A MX2018015469 A MX 2018015469A MX 2018015469 A MX2018015469 A MX 2018015469A MX 2018015469 A MX2018015469 A MX 2018015469A
- Authority
- MX
- Mexico
- Prior art keywords
- vaccine
- dose volume
- low dose
- acid stable
- buffer free
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 229940124859 Rotavirus vaccine Drugs 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 6
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 1
- 229940069428 antacid Drugs 0.000 abstract 1
- 239000003159 antacid agent Substances 0.000 abstract 1
- 230000001458 anti-acid effect Effects 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se devala una vacuna de rotavirus sin tampón, estable al ácido, de volumen de dosis bajo. La vacuna está disponible en un volumen de dosis de menos de 1 ml por dosis para su administración oral y está sin ningún tampón. La vacuna tampoco requiere pre o post administración de ningún antiácido en el momento de la administración oral de la vacuna al sujeto para neutralizar el ácido del estómago. La vacuna ejemplifica una caída nominal en la titulación de la vacuna a pH 2-4 durante un período de tiempo de 30 minutos. La vacuna es estable a -20 ºC durante al menos 60 meses.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201641020675 | 2016-06-16 | ||
| PCT/IN2017/050237 WO2017216808A1 (en) | 2016-06-16 | 2017-06-13 | A buffer free, acid stable low dose volume rotavirus vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018015469A true MX2018015469A (es) | 2019-04-24 |
Family
ID=60664101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018015469A MX2018015469A (es) | 2016-06-16 | 2017-06-13 | Una vacuna de rotavirus sin tampón, de volumen de dosis bajo y estable al ácido. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11351245B2 (es) |
| EP (1) | EP3471768A4 (es) |
| JP (1) | JP7108549B2 (es) |
| KR (3) | KR20190020046A (es) |
| CN (1) | CN109562159B (es) |
| AU (1) | AU2017285408B2 (es) |
| BR (1) | BR112018076094A2 (es) |
| CA (1) | CA3027703A1 (es) |
| CO (1) | CO2019000078A2 (es) |
| EA (1) | EA201990027A1 (es) |
| GB (1) | GB2566244B (es) |
| IL (1) | IL263740B2 (es) |
| JO (1) | JOP20180124A1 (es) |
| MA (1) | MA44557B1 (es) |
| MX (1) | MX2018015469A (es) |
| MY (1) | MY198419A (es) |
| PH (1) | PH12018502650A1 (es) |
| SG (2) | SG10202012281TA (es) |
| TN (1) | TN2018000436A1 (es) |
| UA (1) | UA124430C2 (es) |
| WO (1) | WO2017216808A1 (es) |
| ZA (1) | ZA201900176B (es) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6616931B1 (en) | 1996-09-26 | 2003-09-09 | Merck & Co., Inc. | Rotavirus vaccine formulations |
| ES2294801T3 (es) | 1996-09-26 | 2008-04-01 | MERCK & CO., INC. | Formulaciones de vacunas contra rotavirus. |
| US6403098B1 (en) | 1996-09-26 | 2002-06-11 | Merck & Co., Inc. | Rotavirus vaccine formulations |
| EP0878541A4 (en) * | 1996-10-18 | 2001-10-17 | Univ Osaka Res Found | ROTAVIRUS ANTIGENS, VACCINES AND MEDICINES FOR DIAGNOSING ROTAVIRUS INFECTION AND METHODS OF PREPARING THE SAME |
| BRPI9912485B8 (pt) * | 1998-07-28 | 2021-05-25 | The Government Of The Us Secretary Department Of Health And Human Services | composição imunogênica multivalente |
| WO2001012797A2 (en) | 1999-08-17 | 2001-02-22 | Smithkline Beecham Biologicals S.A. | Method of separating rotavirus variants and live attenuated rotavirus vaccine |
| JP2005038411A (ja) | 2003-06-30 | 2005-02-10 | Sony Corp | 機器認証情報組込システム、端末機器、機器認証情報処理方法、機器認証情報処理プログラム、提供サーバ、機器認証情報提供方法、機器認証情報提供プログラム、及び記憶媒体 |
| GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
| GB0516944D0 (en) * | 2005-08-17 | 2005-09-28 | Glaxosmithkline Biolog Sa | Vaccine |
| BRPI0711608B8 (pt) | 2006-05-12 | 2021-05-25 | Bharat Biotech Int Ltd | composição liofilizada, uso de antígeno viral, método de tratamento ou prevenção de vírus associado, método de adaptação de um vírus de uma linhagem celular adequada |
| CN101638638A (zh) * | 2008-07-29 | 2010-02-03 | 辽宁依生生物制药有限公司 | 人猪重配轮状病毒 |
| US9598676B2 (en) | 2009-07-13 | 2017-03-21 | Bharat Biotech International Limited | Composition useful as rotavirus vaccine and a method therefor |
| JP2014512410A (ja) * | 2011-04-28 | 2014-05-22 | インターナショナル メディカ ファウンデーション | 液体ワクチン調製物 |
| EP2945650B1 (en) * | 2012-04-23 | 2023-07-05 | Bharat Biotech International Limited | Rotavirus vaccine compositions and process for preparing the same |
-
2017
- 2017-06-12 MA MA44557A patent/MA44557B1/fr unknown
- 2017-06-13 BR BR112018076094-3A patent/BR112018076094A2/pt unknown
- 2017-06-13 TN TNP/2018/000436A patent/TN2018000436A1/en unknown
- 2017-06-13 CN CN201780050188.2A patent/CN109562159B/zh active Active
- 2017-06-13 KR KR1020197001395A patent/KR20190020046A/ko not_active IP Right Cessation
- 2017-06-13 MY MYPI2018002561A patent/MY198419A/en unknown
- 2017-06-13 WO PCT/IN2017/050237 patent/WO2017216808A1/en unknown
- 2017-06-13 GB GB1900562.8A patent/GB2566244B/en active Active
- 2017-06-13 EP EP17812897.1A patent/EP3471768A4/en active Pending
- 2017-06-13 CA CA3027703A patent/CA3027703A1/en active Pending
- 2017-06-13 US US16/310,039 patent/US11351245B2/en active Active
- 2017-06-13 EA EA201990027A patent/EA201990027A1/ru unknown
- 2017-06-13 SG SG10202012281TA patent/SG10202012281TA/en unknown
- 2017-06-13 SG SG11201811188TA patent/SG11201811188TA/en unknown
- 2017-06-13 AU AU2017285408A patent/AU2017285408B2/en active Active
- 2017-06-13 KR KR1020227015137A patent/KR20220063302A/ko active Application Filing
- 2017-06-13 KR KR1020237028691A patent/KR20230125863A/ko not_active Application Discontinuation
- 2017-06-13 JP JP2018565803A patent/JP7108549B2/ja active Active
- 2017-06-13 IL IL263740A patent/IL263740B2/en unknown
- 2017-06-13 MX MX2018015469A patent/MX2018015469A/es unknown
- 2017-06-13 UA UAA201900420A patent/UA124430C2/uk unknown
-
2018
- 2018-12-14 PH PH12018502650A patent/PH12018502650A1/en unknown
- 2018-12-16 JO JOP/2018/0124A patent/JOP20180124A1/ar unknown
-
2019
- 2019-01-08 CO CONC2019/0000078A patent/CO2019000078A2/es unknown
- 2019-01-10 ZA ZA2019/00176A patent/ZA201900176B/en unknown
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