MX2018009860A - Anticuerpos para il-17c. - Google Patents

Anticuerpos para il-17c.

Info

Publication number
MX2018009860A
MX2018009860A MX2018009860A MX2018009860A MX2018009860A MX 2018009860 A MX2018009860 A MX 2018009860A MX 2018009860 A MX2018009860 A MX 2018009860A MX 2018009860 A MX2018009860 A MX 2018009860A MX 2018009860 A MX2018009860 A MX 2018009860A
Authority
MX
Mexico
Prior art keywords
antibodies
antibody fragments
psoriasis
humans
human
Prior art date
Application number
MX2018009860A
Other languages
English (en)
Spanish (es)
Inventor
Klattig Jürgen
Ernest René Vandeghinste Nick
Dominik Haas Jan
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of MX2018009860A publication Critical patent/MX2018009860A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2018009860A 2016-02-19 2017-02-17 Anticuerpos para il-17c. MX2018009860A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16156582 2016-02-19
EP16156651 2016-02-22
PCT/EP2017/053592 WO2017140831A1 (en) 2016-02-19 2017-02-17 Antibodies for il-17c

Publications (1)

Publication Number Publication Date
MX2018009860A true MX2018009860A (es) 2019-03-28

Family

ID=58057136

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018009860A MX2018009860A (es) 2016-02-19 2017-02-17 Anticuerpos para il-17c.

Country Status (33)

Country Link
US (5) US20190048071A1 (https=)
EP (1) EP3416983B1 (https=)
JP (2) JP6535139B2 (https=)
KR (1) KR102715157B1 (https=)
CN (1) CN108699143B (https=)
AU (1) AU2017219837B2 (https=)
BR (1) BR112018016798A2 (https=)
CA (1) CA3014842A1 (https=)
CL (1) CL2018002340A1 (https=)
CO (1) CO2018008724A2 (https=)
CU (1) CU20180087A7 (https=)
CY (1) CY1124296T1 (https=)
DK (1) DK3416983T3 (https=)
EA (1) EA037813B1 (https=)
EC (1) ECSP18070641A (https=)
ES (1) ES2877376T3 (https=)
HR (1) HRP20211059T1 (https=)
HU (1) HUE054755T2 (https=)
IL (1) IL260733B2 (https=)
LT (1) LT3416983T (https=)
MA (2) MA44227B1 (https=)
MD (1) MD3416983T2 (https=)
MX (1) MX2018009860A (https=)
PH (1) PH12018501739A1 (https=)
PL (1) PL3416983T3 (https=)
RS (1) RS62012B1 (https=)
SG (1) SG11201806161TA (https=)
SI (1) SI3416983T1 (https=)
SM (1) SMT202100361T1 (https=)
TN (1) TN2018000289A1 (https=)
TW (1) TW201734041A (https=)
WO (1) WO2017140831A1 (https=)
ZA (1) ZA201806249B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10604566B2 (en) * 2015-10-05 2020-03-31 Galapagos Nv Antagonists of IL-17C for the treatment and/or prevention of atopic dermatitis
HRP20211059T1 (hr) * 2016-02-19 2021-10-01 Morphosys Ag Antitijela za il-17c
TW201919698A (zh) * 2017-09-25 2019-06-01 德商莫菲西斯公司 異位性皮炎之治療
GB201803563D0 (en) 2018-03-06 2018-04-18 Galapagos Nv Antibodies and pharmaceutical compositions thereof for the treatment of autoimmune skin diseases
TW202011995A (zh) * 2018-07-03 2020-04-01 比利時商葛萊伯格有限公司 高濃度液體抗體配製物
IL292940A (en) * 2019-11-22 2022-07-01 Morphosys Ag Collection of extractant during antibody chromatography
EP4061825A1 (en) * 2019-11-22 2022-09-28 MorphoSys AG Method to increase antibody yield during ion exchange chromatography

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
EP1958962A3 (en) 1997-06-12 2013-05-01 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
AU740405B2 (en) 1998-05-15 2001-11-01 Genentech Inc. IL-17 homologous polypeptides and therapeutic uses thereof
ES2327382T3 (es) 1999-07-20 2009-10-29 Morphosys Ag Metodos para presentar (poli)peptidos/proteinas en particulas de bacteriofagos a traves de enlaces disulfuro.
US7771951B2 (en) 2001-12-03 2010-08-10 Amgen Fremont Inc. Antibody categorization based on binding characteristics
AU2005295421A1 (en) 2004-10-18 2006-04-27 Zymogenetics, Inc. Soluble Zcytor21, anti-Zcytor21 antibodies and binding partners and methods of using in inflammation
US20070129302A1 (en) * 2005-10-18 2007-06-07 Zeren Gao Il-17c antagonists and methods of using the same
EP2064237A2 (en) 2006-10-18 2009-06-03 ZymoGenetics, Inc. Il-17c antagonists and methods of using the same
US20120201821A1 (en) * 2010-10-25 2012-08-09 Gonzalez Jr Lino Treatment of Gastrointestinal Inflammation and Psoriasis and Asthma
US8367586B2 (en) 2010-11-19 2013-02-05 Morphosys Ag Collection and methods for its use
WO2013016220A1 (en) 2011-07-22 2013-01-31 Amgen Inc. Il-17 receptor a is required for il-17c biology
ME03073B (me) * 2011-10-19 2019-01-20 Galapagos Nv Ant agonisti il17с za lečenje zapaljenskih poremećaja
JP2015521591A (ja) * 2012-06-12 2015-07-30 オレガ・バイオテック Il−17アイソフォームのアンタゴニストおよびその使用
EP3233915B1 (en) * 2014-12-15 2024-08-28 MorphoSys AG Antibodies for il-17c
HRP20211059T1 (hr) 2016-02-19 2021-10-01 Morphosys Ag Antitijela za il-17c

Also Published As

Publication number Publication date
KR20180109977A (ko) 2018-10-08
JP2019511910A (ja) 2019-05-09
RS62012B1 (sr) 2021-07-30
CN108699143B (zh) 2021-11-09
WO2017140831A1 (en) 2017-08-24
LT3416983T (lt) 2021-07-12
ECSP18070641A (es) 2018-10-31
CN108699143A (zh) 2018-10-23
CU20180087A7 (es) 2019-03-04
US20190202906A1 (en) 2019-07-04
MA44227B1 (fr) 2021-06-30
IL260733B2 (en) 2024-03-01
US10633439B2 (en) 2020-04-28
US10259869B2 (en) 2019-04-16
MA44227A (fr) 2018-12-26
SMT202100361T1 (it) 2021-07-12
EA201891594A1 (ru) 2019-01-31
EP3416983B1 (en) 2021-04-07
US20250074978A1 (en) 2025-03-06
EP3416983A1 (en) 2018-12-26
JP6535139B2 (ja) 2019-06-26
IL260733B1 (en) 2023-11-01
DK3416983T3 (en) 2021-06-21
MD3416983T2 (ro) 2021-08-31
CL2018002340A1 (es) 2018-11-23
CY1124296T1 (el) 2022-11-25
TN2018000289A1 (en) 2020-01-16
PL3416983T3 (pl) 2021-10-25
SG11201806161TA (en) 2018-08-30
KR102715157B1 (ko) 2024-10-10
JP2019162119A (ja) 2019-09-26
CO2018008724A2 (es) 2018-08-31
ES2877376T3 (es) 2021-11-16
AU2017219837B2 (en) 2023-08-17
US11987621B2 (en) 2024-05-21
BR112018016798A2 (en) 2018-12-26
IL260733A (https=) 2018-09-20
HUE054755T2 (hu) 2021-09-28
PH12018501739A1 (en) 2019-06-10
MA43088B1 (fr) 2020-10-28
ZA201806249B (en) 2020-02-26
MA43088A1 (fr) 2019-05-31
SI3416983T1 (sl) 2021-08-31
HRP20211059T1 (hr) 2021-10-01
JP6916834B2 (ja) 2021-08-11
EA037813B1 (ru) 2021-05-24
US20190048071A1 (en) 2019-02-14
CA3014842A1 (en) 2017-08-24
TW201734041A (zh) 2017-10-01
US20180340024A1 (en) 2018-11-29
US20200216529A1 (en) 2020-07-09
AU2017219837A1 (en) 2018-08-09

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