LT3416983T - Il-17c antikūnai - Google Patents

Il-17c antikūnai

Info

Publication number
LT3416983T
LT3416983T LTEP17705873.2T LT17705873T LT3416983T LT 3416983 T LT3416983 T LT 3416983T LT 17705873 T LT17705873 T LT 17705873T LT 3416983 T LT3416983 T LT 3416983T
Authority
LT
Lithuania
Prior art keywords
antibodies
Prior art date
Application number
LTEP17705873.2T
Other languages
English (en)
Inventor
Jan Dominik HAAS
Jürgen KLATTIG
Nick Ernest René Vandeghinste
Original Assignee
Morphosys Ag
Galapagos Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag, Galapagos Nv filed Critical Morphosys Ag
Publication of LT3416983T publication Critical patent/LT3416983T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
LTEP17705873.2T 2016-02-19 2017-02-17 Il-17c antikūnai LT3416983T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16156582 2016-02-19
EP16156651 2016-02-22
PCT/EP2017/053592 WO2017140831A1 (en) 2016-02-19 2017-02-17 Antibodies for il-17c

Publications (1)

Publication Number Publication Date
LT3416983T true LT3416983T (lt) 2021-07-12

Family

ID=58057136

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP17705873.2T LT3416983T (lt) 2016-02-19 2017-02-17 Il-17c antikūnai

Country Status (32)

Country Link
US (4) US20190048071A1 (lt)
EP (1) EP3416983B1 (lt)
JP (2) JP6535139B2 (lt)
KR (1) KR20180109977A (lt)
CN (1) CN108699143B (lt)
AU (1) AU2017219837B2 (lt)
BR (1) BR112018016798A2 (lt)
CA (1) CA3014842A1 (lt)
CL (1) CL2018002340A1 (lt)
CO (1) CO2018008724A2 (lt)
CU (1) CU20180087A7 (lt)
CY (1) CY1124296T1 (lt)
DK (1) DK3416983T3 (lt)
EA (1) EA037813B1 (lt)
EC (1) ECSP18070641A (lt)
ES (1) ES2877376T3 (lt)
HR (1) HRP20211059T1 (lt)
HU (1) HUE054755T2 (lt)
IL (1) IL260733B2 (lt)
LT (1) LT3416983T (lt)
MA (2) MA44227B1 (lt)
MD (1) MD3416983T2 (lt)
MX (1) MX2018009860A (lt)
PH (1) PH12018501739A1 (lt)
PL (1) PL3416983T3 (lt)
RS (1) RS62012B1 (lt)
SG (1) SG11201806161TA (lt)
SI (1) SI3416983T1 (lt)
TN (1) TN2018000289A1 (lt)
TW (1) TW201734041A (lt)
WO (1) WO2017140831A1 (lt)
ZA (1) ZA201806249B (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018009860A (es) * 2016-02-19 2019-03-28 Morphosys Ag Anticuerpos para il-17c.
WO2019057982A1 (en) 2017-09-25 2019-03-28 Morphosys Ag TREATMENT OF ATOPIC DERMATITIS
GB201803563D0 (en) 2018-03-06 2018-04-18 Galapagos Nv Antibodies and pharmaceutical compositions thereof for the treatment of autoimmune skin diseases
TW202011995A (zh) * 2018-07-03 2020-04-01 比利時商葛萊伯格有限公司 高濃度液體抗體配製物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
JP3614866B2 (ja) 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ,インコーポレイティド 人工抗体ポリペプチド
DE69936382T3 (de) * 1998-05-15 2011-07-07 Genentech, Inc., Calif. Therapeutische verwendungen von il-17 homologe polypeptide
ES2327382T3 (es) 1999-07-20 2009-10-29 Morphosys Ag Metodos para presentar (poli)peptidos/proteinas en particulas de bacteriofagos a traves de enlaces disulfuro.
ES2307832T3 (es) 2001-12-03 2008-12-01 Amgen Fremont Inc. Clasificacion de anticuerpos basada en las caracteristicas de union.
KR20070084330A (ko) 2004-10-18 2007-08-24 지모제넥틱스, 인코포레이티드 가용성 zcytor21, 항-zcytor21 항체 및 결합파트너 및 염증에서의 사용방법
WO2007047738A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
EP2064237A2 (en) 2006-10-18 2009-06-03 ZymoGenetics, Inc. Il-17c antagonists and methods of using the same
EP2633317A1 (en) * 2010-10-25 2013-09-04 Genentech, Inc. Treatment of gastrointestinal inflammation and psoriasis a
US8728981B2 (en) 2010-11-19 2014-05-20 Morphosys Ag Collection and methods for its use
US20140234330A1 (en) 2011-07-22 2014-08-21 Amgen Inc. Il-17 receptor a is required for il-17c biology
SI2768859T1 (en) * 2011-10-19 2018-06-29 Morphosys Ag IL17C ANTAGONISTS FOR TREATMENT OF INFLAMATORY DISORDERS
US9834601B2 (en) 2012-06-12 2017-12-05 Orega Biotech Antagonists of IL-17 isoforms and their uses
JP6944747B2 (ja) * 2014-12-15 2021-10-06 モルフォシス・アーゲー Il−17cに対する抗体
MX2018009860A (es) * 2016-02-19 2019-03-28 Morphosys Ag Anticuerpos para il-17c.

Also Published As

Publication number Publication date
KR20180109977A (ko) 2018-10-08
JP2019511910A (ja) 2019-05-09
EP3416983B1 (en) 2021-04-07
SG11201806161TA (en) 2018-08-30
JP2019162119A (ja) 2019-09-26
AU2017219837B2 (en) 2023-08-17
AU2017219837A1 (en) 2018-08-09
SI3416983T1 (sl) 2021-08-31
IL260733A (lt) 2018-09-20
EA201891594A1 (ru) 2019-01-31
US20180340024A1 (en) 2018-11-29
RS62012B1 (sr) 2021-07-30
US20200216529A1 (en) 2020-07-09
PL3416983T3 (pl) 2021-10-25
JP6916834B2 (ja) 2021-08-11
JP6535139B2 (ja) 2019-06-26
ES2877376T3 (es) 2021-11-16
HRP20211059T1 (hr) 2021-10-01
MA44227A (fr) 2018-12-26
CN108699143B (zh) 2021-11-09
IL260733B2 (en) 2024-03-01
CN108699143A (zh) 2018-10-23
CA3014842A1 (en) 2017-08-24
TW201734041A (zh) 2017-10-01
ZA201806249B (en) 2020-02-26
EA037813B1 (ru) 2021-05-24
CU20180087A7 (es) 2019-03-04
CO2018008724A2 (es) 2018-08-31
IL260733B1 (en) 2023-11-01
US10259869B2 (en) 2019-04-16
MA44227B1 (fr) 2021-06-30
DK3416983T3 (en) 2021-06-21
WO2017140831A1 (en) 2017-08-24
PH12018501739A1 (en) 2019-06-10
EP3416983A1 (en) 2018-12-26
US20190202906A1 (en) 2019-07-04
HUE054755T2 (hu) 2021-09-28
MX2018009860A (es) 2019-03-28
TN2018000289A1 (en) 2020-01-16
MA43088A1 (fr) 2019-05-31
MA43088B1 (fr) 2020-10-28
MD3416983T2 (ro) 2021-08-31
ECSP18070641A (es) 2018-10-31
US20190048071A1 (en) 2019-02-14
BR112018016798A2 (pt) 2018-12-26
CY1124296T1 (el) 2022-11-25
CL2018002340A1 (es) 2018-11-23
US10633439B2 (en) 2020-04-28

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