MX2018008153A - Derivados de c-glicósido que tienen anillos de fenilo condensado o sales farmacéuticamente aceptables de los mismos, metodo para prepararlos y composición farmacéutica que los contiene. - Google Patents

Derivados de c-glicósido que tienen anillos de fenilo condensado o sales farmacéuticamente aceptables de los mismos, metodo para prepararlos y composición farmacéutica que los contiene.

Info

Publication number
MX2018008153A
MX2018008153A MX2018008153A MX2018008153A MX2018008153A MX 2018008153 A MX2018008153 A MX 2018008153A MX 2018008153 A MX2018008153 A MX 2018008153A MX 2018008153 A MX2018008153 A MX 2018008153A MX 2018008153 A MX2018008153 A MX 2018008153A
Authority
MX
Mexico
Prior art keywords
same
pharmaceutically acceptable
pharmaceutical composition
acceptable salt
phenyl ring
Prior art date
Application number
MX2018008153A
Other languages
English (en)
Inventor
Woo Nam Joon
Yup Kim Jong
Hoon Kim Kyung
Mee Lee Jung
Yoon Kim Ji
Seon Park Ji
Kim Joseph
Sun Park Yoon
Min Kim Jeong
Original Assignee
Je Il Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Je Il Pharmaceutical Co Ltd filed Critical Je Il Pharmaceutical Co Ltd
Publication of MX2018008153A publication Critical patent/MX2018008153A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11—Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1107—Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62B—DEVICES, APPARATUS OR METHODS FOR LIFE-SAVING
    • A62B23/00—Filters for breathing-protection purposes
    • A62B23/02—Filters for breathing-protection purposes for respirators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/0002—Casings; Housings; Frame constructions
    • B01D46/0005—Mounting of filtering elements within casings, housings or frames
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/42—Auxiliary equipment or operation thereof
    • B01D46/4227—Manipulating filters or filter elements, e.g. handles or extracting tools
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

La presente divulgación se refiere a derivados de C-glicósido que tienen un anillo fenilo condensado o a sales farmacéuticamente aceptables de los mismos, un método para prepararlos, una composición farmacéutica que los contiene, un uso de los mismos y un método para la inhibición del SGLT1 y del SGLT2 usando los mismos. Un nuevo compuesto de la presente divulgación tiene una doble actividad inhibidora contra el SGLT1 y el SGLT2, por lo que se usa de forma útil como agente terapéutico para la diabetes.
MX2018008153A 2016-01-04 2017-01-03 Derivados de c-glicósido que tienen anillos de fenilo condensado o sales farmacéuticamente aceptables de los mismos, metodo para prepararlos y composición farmacéutica que los contiene. MX2018008153A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160000610 2016-01-04
PCT/KR2017/000065 WO2017119700A1 (ko) 2016-01-04 2017-01-03 융합 페닐 환이 포함된 c-글루코시드 유도체 또는 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 포함하는 약학적 조성물

Publications (1)

Publication Number Publication Date
MX2018008153A true MX2018008153A (es) 2018-11-29

Family

ID=59274089

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018008153A MX2018008153A (es) 2016-01-04 2017-01-03 Derivados de c-glicósido que tienen anillos de fenilo condensado o sales farmacéuticamente aceptables de los mismos, metodo para prepararlos y composición farmacéutica que los contiene.

Country Status (21)

Country Link
US (1) US10752604B2 (es)
EP (1) EP3404033B1 (es)
JP (1) JP6667008B2 (es)
KR (1) KR101987403B1 (es)
CN (1) CN108699098B (es)
AU (1) AU2017205545B2 (es)
BR (1) BR112018013408B1 (es)
CA (1) CA3010323C (es)
DK (1) DK3404033T3 (es)
ES (1) ES2827795T3 (es)
HU (1) HUE051212T2 (es)
IL (1) IL260379B (es)
MX (1) MX2018008153A (es)
MY (1) MY194941A (es)
NZ (1) NZ743987A (es)
PT (1) PT3404033T (es)
RU (1) RU2739024C2 (es)
TR (1) TR201810664T1 (es)
UA (1) UA122083C2 (es)
WO (1) WO2017119700A1 (es)
ZA (1) ZA201804663B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112018013408B1 (pt) 2016-01-04 2024-01-30 Je Il Pharmaceutical Co., Ltd Derivados de c-glicosídeo que têm anel fenila fusionado ou sais farmaceuticamente aceitáveis dos mesmos, método para preparar os mesmos e composição farmacêutica compreendendo os mesmos
AR119011A1 (es) 2019-05-29 2021-11-17 Syngenta Crop Protection Ag DERIVADOS DE [1,3]DIOXOLO[4,5-c]PIRIDIN-4-CARBOXAMIDA, COMPOSICIONES AGROQUÍMICAS QUE LOS COMPRENDEN Y SU EMPLEO COMO FUNGICIDA PARA CONTROLAR O PREVENIR LA INFESTACIÓN DE PLANTAS ÚTILES
JP2023551441A (ja) * 2020-11-19 2023-12-08 ベイジン・インクリーズ・イノベーティブ・ドラッグ・カンパニー，リミテッド グリコシド系誘導体及びその製造方法と応用

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PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
US6515117B2 (en) * 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
US6936590B2 (en) 2001-03-13 2005-08-30 Bristol Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
AR048376A1 (es) 2003-08-01 2006-04-26 Janssen Pharmaceutica Nv C- glicosidos heterociclos fusionados sustituidos
TW200904454A (en) 2007-03-22 2009-02-01 Bristol Myers Squibb Co Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
KR101107425B1 (ko) 2007-08-23 2012-01-19 테라코스, 인코포레이티드 벤질벤젠 유도체 및 사용 방법
DK2334687T5 (da) * 2008-08-28 2012-09-10 Pfizer Dioxa-bicyclo[3.2.1.]octan-2,3,4-triol-derivater
CN102134226B (zh) 2010-01-26 2013-06-12 天津药物研究院 一类苯基c-葡萄糖苷衍生物、其制备方法和用途
CN102372722A (zh) 2010-08-10 2012-03-14 江苏恒瑞医药股份有限公司 C-芳基葡萄糖苷衍生物、其制备方法及其在医药上的应用
WO2012033390A2 (en) * 2010-09-10 2012-03-15 Green Cross Corporation Novel thiophene derivative as sglt2 inhibitor and pharmaceutical composition comprising same
WO2012041898A1 (en) 2010-09-29 2012-04-05 Celon Pharma Sp. Z O.O. Combination of sglt2 inhibitor and a sugar compound for the treatment of diabetes
JPWO2012165356A1 (ja) * 2011-05-27 2015-02-23 国立大学法人九州大学 感温性ポリアミノ酸またはその塩
US9034921B2 (en) * 2011-06-01 2015-05-19 Green Cross Corporation Diphenylmethane derivatives as SGLT2 inhibitors
CN105518014B (zh) * 2013-09-09 2018-03-23 上海研健新药研发有限公司 C‑芳基葡糖苷衍生物、其制备方法及其在医药上的应用
CN106349201B (zh) * 2014-01-03 2018-09-18 山东轩竹医药科技有限公司 光学纯的苄基-4-氯苯基的c-糖苷衍生物
KR20150130177A (ko) * 2014-05-13 2015-11-23 한미약품 주식회사 Sglt 저해제로서 2,3-다이하이드로벤조퓨란 유도체 및 이를 포함하는 약학적 조성물
TW201623321A (zh) * 2014-05-13 2016-07-01 韓美藥品股份有限公司 雙環衍生物及包含其之藥學組成物
BR112018013408B1 (pt) 2016-01-04 2024-01-30 Je Il Pharmaceutical Co., Ltd Derivados de c-glicosídeo que têm anel fenila fusionado ou sais farmaceuticamente aceitáveis dos mesmos, método para preparar os mesmos e composição farmacêutica compreendendo os mesmos
ES2895762T3 (es) 2016-12-20 2022-02-22 Arcelormittal Un procedimiento de fabricación de una lámina de acero tratada térmicamente

Also Published As

Publication number Publication date
UA122083C2 (uk) 2020-09-10
KR20170081574A (ko) 2017-07-12
BR112018013408A2 (pt) 2018-12-11
RU2018127488A3 (es) 2020-01-28
EP3404033A4 (en) 2019-09-04
EP3404033B1 (en) 2020-08-05
JP6667008B2 (ja) 2020-03-18
EP3404033A1 (en) 2018-11-21
HUE051212T2 (hu) 2021-03-01
ZA201804663B (en) 2019-09-25
PT3404033T (pt) 2020-10-30
BR112018013408B1 (pt) 2024-01-30
CA3010323A1 (en) 2017-07-13
TR201810664T1 (tr) 2018-08-27
US10752604B2 (en) 2020-08-25
NZ743987A (en) 2019-10-25
WO2017119700A1 (ko) 2017-07-13
US20190002425A1 (en) 2019-01-03
DK3404033T3 (da) 2020-11-02
CA3010323C (en) 2021-08-10
AU2017205545B2 (en) 2019-11-21
CN108699098B (zh) 2022-01-25
RU2018127488A (ru) 2020-01-28
JP2019502757A (ja) 2019-01-31
IL260379B (en) 2021-04-29
RU2739024C2 (ru) 2020-12-21
CN108699098A (zh) 2018-10-23
KR101987403B1 (ko) 2019-06-10
ES2827795T3 (es) 2021-05-24
AU2017205545A1 (en) 2018-07-19
MY194941A (en) 2022-12-27

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