MX2018003101A - Activo de polipeptidos de lisina contra bacterias gram-negativas. - Google Patents
Activo de polipeptidos de lisina contra bacterias gram-negativas.Info
- Publication number
- MX2018003101A MX2018003101A MX2018003101A MX2018003101A MX2018003101A MX 2018003101 A MX2018003101 A MX 2018003101A MX 2018003101 A MX2018003101 A MX 2018003101A MX 2018003101 A MX2018003101 A MX 2018003101A MX 2018003101 A MX2018003101 A MX 2018003101A
- Authority
- MX
- Mexico
- Prior art keywords
- negative bacteria
- lysin polypeptides
- active against
- against gram
- gram
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente descripción proporciona métodos y composiciones útiles para la mejora profiláctica y terapéutica y tratamiento de infecciones causadas por bacterias Gram-negativas, que incluyen Pseudomonas aeruginosa. La descripción proporciona además composiciones y métodos para incorporar y utilizar polipéptidos de lisina de la presente descripción para aumentar la eficacia de antibióticos generalmente adecuados para el tratamiento de la infección bacteriana Gram-negativa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562220212P | 2015-09-17 | 2015-09-17 | |
US201562247619P | 2015-10-28 | 2015-10-28 | |
PCT/US2016/052338 WO2017049233A2 (en) | 2015-09-17 | 2016-09-16 | Lysin polypeptides active against gram-negative bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018003101A true MX2018003101A (es) | 2018-12-17 |
Family
ID=57121513
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018003100A MX2018003100A (es) | 2015-09-17 | 2016-09-16 | Uso de lisina para restaurar/aumentar la actividad antibacteriana en presencia de agente tensoactivo pulmonar de antibioticos inhibidos en el mismo. |
MX2018003101A MX2018003101A (es) | 2015-09-17 | 2016-09-16 | Activo de polipeptidos de lisina contra bacterias gram-negativas. |
MX2022006525A MX2022006525A (es) | 2015-09-17 | 2018-03-13 | Activo de polipeptidos de lisina contra bacterias gram-negativas. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018003100A MX2018003100A (es) | 2015-09-17 | 2016-09-16 | Uso de lisina para restaurar/aumentar la actividad antibacteriana en presencia de agente tensoactivo pulmonar de antibioticos inhibidos en el mismo. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022006525A MX2022006525A (es) | 2015-09-17 | 2018-03-13 | Activo de polipeptidos de lisina contra bacterias gram-negativas. |
Country Status (15)
Country | Link |
---|---|
US (5) | US11357833B2 (es) |
EP (4) | EP3349781A2 (es) |
JP (3) | JP2018534247A (es) |
KR (2) | KR20180064417A (es) |
CN (3) | CN116077630A (es) |
AU (3) | AU2016324307B2 (es) |
BR (2) | BR112018005318A2 (es) |
CA (2) | CA2998507A1 (es) |
ES (1) | ES2934714T3 (es) |
HK (1) | HK1256628A1 (es) |
IL (2) | IL258123B (es) |
MX (3) | MX2018003100A (es) |
RU (2) | RU2728682C2 (es) |
WO (2) | WO2017049233A2 (es) |
ZA (2) | ZA201801315B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2013170022A1 (en) * | 2012-05-09 | 2013-11-14 | Contrafect Corporation | Biofilm prevention, disruption and treatment with bacteriophage lysin |
CA2953446A1 (en) * | 2014-06-26 | 2015-12-30 | The Rockefeller University | Acinetobacter lysins |
CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
RU2728682C2 (ru) | 2015-09-17 | 2020-07-31 | Контрафект Корпорейшн | Применение лизина для восстановления/увеличения антибактериальной активности антибиотиков в присутствии легочного сурфактанта, который ингибирует указанные антибиотики |
BR112020011433A2 (pt) * | 2017-12-12 | 2020-12-01 | Contrafect Corporation | identificação de lisinas e seus derivados com atividade bacteriana contra pseudomonas aeruginosa |
WO2019126670A1 (en) | 2017-12-22 | 2019-06-27 | The Rockefeller University | Recombinant pseudomonas aeruginosa lysins |
EP3731843A4 (en) | 2017-12-28 | 2021-11-17 | Consegna Pharma Inc. | LONG-TERM OPIOID ANTAGONISTS |
US10988520B2 (en) | 2018-03-29 | 2021-04-27 | Contrafect Corporation | Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
AU2019245369A1 (en) * | 2018-03-29 | 2020-10-29 | Contrafect Corporation | Lysin-antimicrobial peptide (AMP) polypeptide constructs, lysins, isolated polynucleotides encoding same and uses thereof |
AU2019245333A1 (en) * | 2018-03-29 | 2020-10-29 | Contrafect Corporation | Antimicrobial, bacteriophage-derived polypeptides and their use against gram-negative bacteria |
EP3813796A4 (en) * | 2018-05-23 | 2022-06-22 | The Rockefeller University | RECOMBINANT LYSINE |
KR20210024005A (ko) * | 2018-06-22 | 2021-03-04 | 콘트라펙트 코포레이션 | 스태필로코커스 아우레우스 및 그람 양성 세균을 항생제에 재민감화시키기 위한 리신 및 이의 유도체 |
CN110664881A (zh) * | 2018-07-03 | 2020-01-10 | 上海海洋大学 | 抗水产致病性弗氏柠檬酸杆菌的药物及其制备方法 |
EP3840771A4 (en) * | 2018-08-23 | 2023-04-19 | Contrafect Corporation | ANTIMICROBIAL LYSINE-PEPTIDE (AMP) POLYPEPTIDE CONSTRUCTIONS, LYSINES, ISOLATED POLYNUCLEOTIDES ENCODING THEM AND THEIR USES |
US20220024992A1 (en) * | 2018-11-02 | 2022-01-27 | The Rockefeller University | Compositions and methods comprising lysocins as bioengineered antimicrobials for use in targeting gram-negative bacteria |
CA3134154A1 (en) * | 2019-03-22 | 2020-10-01 | Contrafect Corporation | Method of treating infective endocarditis |
CA3136126A1 (en) * | 2019-04-05 | 2020-10-08 | Contrafect Corporation | Lysins and derivatives thereof with bactericidal activity against pseudomonas aeruginosa, in the presence of human serum |
EP3996740A4 (en) * | 2019-07-12 | 2023-07-05 | Contrafect Corporation | THERAPEUTIC PROTEIN FORMULATIONS INCLUDING ANTIBODIES AND THEIR USES |
CN110684760A (zh) * | 2019-09-27 | 2020-01-14 | 吉林大学 | 一种杀灭葡萄球菌的基因工程裂解酶及制备方法和应用 |
EP4118192A1 (en) | 2020-03-11 | 2023-01-18 | Telum Therapeutics S.L. | New recombinant lysin and its use in the treatment of gram-negative bacterial infections |
WO2021207679A1 (en) * | 2020-04-10 | 2021-10-14 | Liberty Biosecurity, Llc | Polypeptide compositions and uses thereof |
US20210324359A1 (en) * | 2020-04-17 | 2021-10-21 | Contrafect Corporation | Use of gram-negative lysin-antimicrobial peptide (amp) polypeptide constructs in treating endocarditis |
KR102224897B1 (ko) * | 2020-05-22 | 2021-03-08 | 주식회사 라이센텍 | 신규한 폴리펩타이드 및 이를 포함하는 그람음성균에 대한 항생제 |
KR102228999B1 (ko) * | 2020-08-27 | 2021-03-18 | 주식회사 라이센텍 | 폴리펩타이드 변이체 및 이를 포함하는 그람음성균에 대한 항생제 |
CA3184447A1 (en) * | 2020-05-22 | 2021-11-25 | Lysentech Co., Ltd. | Novel polypeptide, fusion polypeptide, and antibiotic against gram-negative bacteria comprising same |
KR102419028B1 (ko) * | 2021-01-06 | 2022-07-08 | 주식회사 리신바이오 | 박테리오파지 유래 신규 재조합 엔도라이신 및 이의 용도 |
US11452757B2 (en) * | 2021-02-25 | 2022-09-27 | Intron Biotechnology, Inc. | Antibacterial composition effective in treating gram negative bacterial infections and method for preparing the same |
KR20230024845A (ko) * | 2021-08-09 | 2023-02-21 | 주식회사 레고켐 바이오사이언스 | 신규 항생제 및 이의 용도 |
WO2023034646A2 (en) * | 2021-09-03 | 2023-03-09 | Aanika Biosciences, Inc. | Lysecd7 variants and methods of using the same |
US11548917B1 (en) * | 2021-11-24 | 2023-01-10 | Intron Biotechnology, Inc. | Antibacterial composition effective in treating gram negative bacterial infections and method for preparing the same |
WO2023139605A1 (en) * | 2022-01-20 | 2023-07-27 | Techinvention Lifecare Pvt. Ltd. | Lysin polypeptides and compositions thereof against urinary tract infection caused by drug-resistant gram- negative bacteria |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
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US20040076590A1 (en) | 2002-07-08 | 2004-04-22 | Wilkins Joe S. | Antibacterial toothpaste and mouthwash formulations |
CN101094427B (zh) | 2006-06-23 | 2010-05-12 | 华为技术有限公司 | 全网信令消息采集系统及方法 |
HUE031136T2 (en) | 2007-07-26 | 2017-07-28 | Revance Therapeutics Inc | Antimicrobial peptide and preparations |
BRPI1015192A2 (pt) * | 2009-06-26 | 2019-09-17 | Katholieke Univ Leuven K U Leuven R&D | agentes antimicrobianos |
AU2010288559B8 (en) | 2009-08-24 | 2015-08-13 | Katholieke Universiteit Leuven, K.U. Leuven R&D | New endolysin OBPgpLYS |
CN102021161A (zh) | 2009-09-22 | 2011-04-20 | 昆山博青生物科技有限公司 | 一种制备肺炎链球菌噬菌体裂解酶的方法 |
PT3443970T (pt) * | 2010-09-17 | 2020-10-09 | Technophage Investig E Desenvolvimento Em Biotecnologia Sa | Fagos antibacterianos, péptidos fágicos e métodos de utilização dos mesmos |
EP2468856A1 (en) | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
WO2012114833A1 (ja) * | 2011-02-22 | 2012-08-30 | Dic株式会社 | 水性ウレタン樹脂組成物及びそれを用いて得られるフィルム及び光学フィルム |
CN108578685A (zh) | 2011-04-21 | 2018-09-28 | 洛克菲勒大学 | 用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素 |
EP2993181A1 (en) | 2011-04-27 | 2016-03-09 | Lysando AG | New antimicrobial agents |
WO2013044055A2 (en) | 2011-09-23 | 2013-03-28 | Quantum Engineered Products, Inc. | Low profile jack |
AU2013259512B2 (en) * | 2012-05-09 | 2018-01-25 | Contrafect Corporation | Bacteriophage lysin and antibiotic combinations against gram positive bacteria |
EP2679677A1 (en) | 2012-06-29 | 2014-01-01 | Lysando Aktiengesellschaft | Composition for use in Mycobacteria therapy |
US9139626B2 (en) * | 2012-09-13 | 2015-09-22 | The Mitre Corporation | Mitrecin A polypeptide with antimicrobial activity |
EP2951548A2 (en) | 2013-01-29 | 2015-12-09 | Wideco Sweden AB | System for monitoring pipeline leakage, pipeline element provided with the system, and method for mounting the monitoring system onto a pipeline |
CN105101796B (zh) * | 2013-02-06 | 2017-06-06 | 中央研究院 | 衍生自b型肝炎病毒核蛋白精氨酸密集区的抗菌胜肽 |
WO2015070912A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified el188 endolysin sequence |
WO2015070911A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified kz144 endolysin sequence |
RU2728682C2 (ru) * | 2015-09-17 | 2020-07-31 | Контрафект Корпорейшн | Применение лизина для восстановления/увеличения антибактериальной активности антибиотиков в присутствии легочного сурфактанта, который ингибирует указанные антибиотики |
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2016
- 2016-09-16 RU RU2018107249A patent/RU2728682C2/ru active
- 2016-09-16 MX MX2018003100A patent/MX2018003100A/es unknown
- 2016-09-16 EP EP16781597.6A patent/EP3349781A2/en not_active Withdrawn
- 2016-09-16 JP JP2018513834A patent/JP2018534247A/ja active Pending
- 2016-09-16 KR KR1020187010860A patent/KR20180064417A/ko not_active Application Discontinuation
- 2016-09-16 WO PCT/US2016/052338 patent/WO2017049233A2/en active Application Filing
- 2016-09-16 RU RU2018107245A patent/RU2724545C2/ru active
- 2016-09-16 BR BR112018005318-0A patent/BR112018005318A2/pt active Search and Examination
- 2016-09-16 EP EP16778940.3A patent/EP3349780B1/en active Active
- 2016-09-16 EP EP22177375.7A patent/EP4115897A1/en active Pending
- 2016-09-16 EP EP22198866.0A patent/EP4151228A3/en active Pending
- 2016-09-16 CN CN202211342042.4A patent/CN116077630A/zh active Pending
- 2016-09-16 US US15/760,416 patent/US11357833B2/en active Active
- 2016-09-16 CA CA2998507A patent/CA2998507A1/en active Pending
- 2016-09-16 AU AU2016324307A patent/AU2016324307B2/en active Active
- 2016-09-16 AU AU2016324298A patent/AU2016324298B2/en active Active
- 2016-09-16 ES ES16778940T patent/ES2934714T3/es active Active
- 2016-09-16 CA CA2998484A patent/CA2998484A1/en active Pending
- 2016-09-16 WO PCT/US2016/052348 patent/WO2017049242A2/en active Application Filing
- 2016-09-16 US US15/760,283 patent/US10744189B2/en active Active
- 2016-09-16 MX MX2018003101A patent/MX2018003101A/es unknown
- 2016-09-16 CN CN201680054495.3A patent/CN108348574B/zh active Active
- 2016-09-16 KR KR1020187010861A patent/KR20180052754A/ko not_active Application Discontinuation
- 2016-09-16 JP JP2018513835A patent/JP7029805B2/ja active Active
- 2016-09-16 CN CN201680054182.8A patent/CN108135971A/zh active Pending
- 2016-09-16 BR BR112018005316-3A patent/BR112018005316A2/pt active Search and Examination
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2018
- 2018-02-26 ZA ZA2018/01315A patent/ZA201801315B/en unknown
- 2018-02-26 ZA ZA2018/01316A patent/ZA201801316B/en unknown
- 2018-03-13 MX MX2022006525A patent/MX2022006525A/es unknown
- 2018-03-14 IL IL258123A patent/IL258123B/en active IP Right Grant
- 2018-03-14 IL IL258122A patent/IL258122B/en active IP Right Grant
- 2018-12-10 HK HK18115762.4A patent/HK1256628A1/zh unknown
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2020
- 2020-07-09 US US16/924,681 patent/US11413334B2/en active Active
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2022
- 2022-02-14 JP JP2022020105A patent/JP2022065075A/ja active Pending
- 2022-05-20 US US17/749,252 patent/US20220362352A1/en active Pending
- 2022-07-08 US US17/811,325 patent/US20230050560A1/en active Pending
- 2022-10-14 AU AU2022252850A patent/AU2022252850A1/en active Pending
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