MX2017016862A - Composicion farmaceutica estable para administracion oral. - Google Patents
Composicion farmaceutica estable para administracion oral.Info
- Publication number
- MX2017016862A MX2017016862A MX2017016862A MX2017016862A MX2017016862A MX 2017016862 A MX2017016862 A MX 2017016862A MX 2017016862 A MX2017016862 A MX 2017016862A MX 2017016862 A MX2017016862 A MX 2017016862A MX 2017016862 A MX2017016862 A MX 2017016862A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical composition
- stable pharmaceutical
- compound
- acceptable salt
- pharmacologically acceptable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporciona una composición farmacéutica estable para administración oral que comprende 6-etil-3-({3-metoxi-4-[4-(4-meti lpiperazin-1-il)piperidin-1-il]fenil}amino)-5-(tetrahidro-2H-pira n-4-ilamino)pirazin-2-carboxamida (de aquí en adelante referida como compuesto A) o una sal farmacéuticamente aceptable de la misma, en donde se inhibe la generación de sustancias relacionadas durante el almacenamiento. En la composición farmacéutica estable para administración oral, la proporción de cristales de compuesto A o una sal farmacéuticamente aceptable de la misma es 60% o más con respecto a la cantidad total del Compuesto A o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015134817 | 2015-07-03 | ||
PCT/JP2016/069615 WO2017006855A1 (ja) | 2015-07-03 | 2016-07-01 | 安定な経口投与用医薬組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017016862A true MX2017016862A (es) | 2018-04-24 |
Family
ID=57686183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017016862A MX2017016862A (es) | 2015-07-03 | 2016-07-01 | Composicion farmaceutica estable para administracion oral. |
Country Status (21)
Country | Link |
---|---|
US (9) | US10786500B2 (es) |
EP (2) | EP3318259B1 (es) |
JP (2) | JP6132294B1 (es) |
KR (1) | KR20180023914A (es) |
CN (1) | CN107847500B (es) |
CA (1) | CA2989534C (es) |
DK (1) | DK3318259T3 (es) |
ES (1) | ES2940306T3 (es) |
FI (1) | FI3318259T3 (es) |
HK (1) | HK1248544A1 (es) |
HR (1) | HRP20230253T1 (es) |
HU (1) | HUE061697T2 (es) |
LT (1) | LT3318259T (es) |
MX (1) | MX2017016862A (es) |
PH (1) | PH12017502252B1 (es) |
PL (1) | PL3318259T3 (es) |
PT (1) | PT3318259T (es) |
RS (1) | RS64070B1 (es) |
SI (1) | SI3318259T1 (es) |
TW (1) | TWI756177B (es) |
WO (1) | WO2017006855A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA120607C2 (uk) * | 2014-02-04 | 2020-01-10 | Астеллас Фарма Інк. | Фармацевтична композиція, яка включає діаміно-гетероциклічну карбоксамідну сполуку як активний інгредієнт |
MX2017016862A (es) * | 2015-07-03 | 2018-04-24 | Astellas Pharma Inc | Composicion farmaceutica estable para administracion oral. |
KR20210148252A (ko) * | 2019-04-03 | 2021-12-07 | 아스텔라스세이야쿠 가부시키가이샤 | 의약 조성물 |
WO2022009235A1 (en) * | 2020-07-10 | 2022-01-13 | Msn Laboratories Private Limited, R&D Center | Process for the preparation of gilteritinib fumarate |
US11945785B2 (en) | 2021-12-30 | 2024-04-02 | Biomea Fusion, Inc. | Pyrazine compounds as inhibitors of FLT3 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2233129B1 (en) * | 2007-12-28 | 2014-05-07 | Sawai Pharmaceutical Co., Ltd. | Oral cavity disintegrating tablet and method of producing the same |
KR101614572B1 (ko) | 2009-05-08 | 2016-04-21 | 아스테라스 세이야쿠 가부시키가이샤 | 디아미노 헤테로환 카르복사미드 화합물 |
LT2661261T (lt) * | 2011-01-07 | 2019-10-25 | Novartis Ag | Imunosupresantų kompozicijos |
UA120607C2 (uk) | 2014-02-04 | 2020-01-10 | Астеллас Фарма Інк. | Фармацевтична композиція, яка включає діаміно-гетероциклічну карбоксамідну сполуку як активний інгредієнт |
TW201613579A (en) | 2014-06-24 | 2016-04-16 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
MX2017016862A (es) | 2015-07-03 | 2018-04-24 | Astellas Pharma Inc | Composicion farmaceutica estable para administracion oral. |
US9755832B2 (en) | 2015-12-29 | 2017-09-05 | International Business Machines Corporation | Password-authenticated public key encryption and decryption |
-
2016
- 2016-07-01 MX MX2017016862A patent/MX2017016862A/es unknown
- 2016-07-01 CA CA2989534A patent/CA2989534C/en active Active
- 2016-07-01 HU HUE16821324A patent/HUE061697T2/hu unknown
- 2016-07-01 PT PT168213247T patent/PT3318259T/pt unknown
- 2016-07-01 SI SI201631667T patent/SI3318259T1/sl unknown
- 2016-07-01 FI FIEP16821324.7T patent/FI3318259T3/fi active
- 2016-07-01 PL PL16821324.7T patent/PL3318259T3/pl unknown
- 2016-07-01 CN CN201680039513.0A patent/CN107847500B/zh active Active
- 2016-07-01 TW TW105121008A patent/TWI756177B/zh active
- 2016-07-01 US US15/741,377 patent/US10786500B2/en active Active
- 2016-07-01 HR HRP20230253TT patent/HRP20230253T1/hr unknown
- 2016-07-01 JP JP2016569102A patent/JP6132294B1/ja active Active
- 2016-07-01 RS RS20230190A patent/RS64070B1/sr unknown
- 2016-07-01 LT LTEPPCT/JP2016/069615T patent/LT3318259T/lt unknown
- 2016-07-01 KR KR1020177037673A patent/KR20180023914A/ko active IP Right Grant
- 2016-07-01 EP EP16821324.7A patent/EP3318259B1/en active Active
- 2016-07-01 WO PCT/JP2016/069615 patent/WO2017006855A1/ja active Application Filing
- 2016-07-01 EP EP23150843.3A patent/EP4230208A1/en active Pending
- 2016-07-01 DK DK16821324.7T patent/DK3318259T3/da active
- 2016-07-01 ES ES16821324T patent/ES2940306T3/es active Active
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2017
- 2017-04-11 JP JP2017077939A patent/JP6798400B2/ja active Active
- 2017-12-11 PH PH12017502252A patent/PH12017502252B1/en unknown
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2018
- 2018-06-26 HK HK18108229.6A patent/HK1248544A1/zh unknown
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2020
- 2020-08-24 US US17/000,763 patent/US20200383977A1/en not_active Abandoned
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2022
- 2022-12-21 US US18/085,842 patent/US20230129146A1/en active Pending
-
2023
- 2023-05-05 US US18/313,132 patent/US20230310422A1/en not_active Abandoned
- 2023-05-12 US US18/316,370 patent/US11938132B2/en active Active
- 2023-05-12 US US18/316,368 patent/US11944620B2/en active Active
- 2023-05-12 US US18/316,357 patent/US11938130B2/en active Active
- 2023-05-12 US US18/316,364 patent/US11938131B2/en active Active
- 2023-05-12 US US18/316,373 patent/US11938133B2/en active Active
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