MX2017015373A - COMPOSICIONES Y MíTODOS PARA LA DEGRADACIíN DE PROTEíNAS MAL PLEGADAS. - Google Patents
COMPOSICIONES Y MíTODOS PARA LA DEGRADACIíN DE PROTEíNAS MAL PLEGADAS.Info
- Publication number
- MX2017015373A MX2017015373A MX2017015373A MX2017015373A MX2017015373A MX 2017015373 A MX2017015373 A MX 2017015373A MX 2017015373 A MX2017015373 A MX 2017015373A MX 2017015373 A MX2017015373 A MX 2017015373A MX 2017015373 A MX2017015373 A MX 2017015373A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- degradation
- misfolded proteins
- proteins
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000015556 catabolic process Effects 0.000 title abstract 2
- 238000006731 degradation reaction Methods 0.000 title abstract 2
- 108091007915 STUbLs Proteins 0.000 abstract 1
- 108091053398 TRIM/RBCC family Proteins 0.000 abstract 1
- 102000011408 Tripartite Motif Proteins Human genes 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
- C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
Abstract
La presente invención se relaciona con composiciones y métodos para promover la degradación de proteínas mal plegadas y agregados de proteína; las composiciones y métodos se pueden usar para tratar un trastorno asociado con proteínas mal plegadas o agregados de proteína; en ciertas instancias, las composiciones y métodos se relacionan con moduladores de una o más proteínas TRIM o una o más STUbLs.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562168309P | 2015-05-29 | 2015-05-29 | |
PCT/US2016/034751 WO2016196328A1 (en) | 2015-05-29 | 2016-05-27 | Compositions and methods for degradation of misfolded proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017015373A true MX2017015373A (es) | 2018-07-06 |
Family
ID=57441753
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017015373A MX2017015373A (es) | 2015-05-29 | 2016-05-27 | COMPOSICIONES Y MíTODOS PARA LA DEGRADACIíN DE PROTEíNAS MAL PLEGADAS. |
MX2021014954A MX2021014954A (es) | 2015-05-29 | 2017-11-29 | Composiciones y metodos para la degradacion de proteinas mal plegadas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021014954A MX2021014954A (es) | 2015-05-29 | 2017-11-29 | Composiciones y metodos para la degradacion de proteinas mal plegadas. |
Country Status (15)
Country | Link |
---|---|
US (2) | US11542500B2 (es) |
EP (1) | EP3302706A4 (es) |
JP (2) | JP7011467B2 (es) |
KR (1) | KR20180011276A (es) |
CN (1) | CN108271364A (es) |
AU (2) | AU2016271635B2 (es) |
BR (1) | BR112017025574A2 (es) |
CA (1) | CA2987057A1 (es) |
HK (1) | HK1252757A1 (es) |
IL (2) | IL255912B2 (es) |
MX (2) | MX2017015373A (es) |
RU (2) | RU2021134920A (es) |
SG (1) | SG10202011833TA (es) |
WO (1) | WO2016196328A1 (es) |
ZA (1) | ZA201708067B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10202007103TA (en) | 2014-11-05 | 2020-09-29 | Voyager Therapeutics Inc | Aadc polynucleotides for the treatment of parkinson's disease |
US10597660B2 (en) | 2014-11-14 | 2020-03-24 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (ALS) |
CA3024448A1 (en) | 2016-05-18 | 2017-11-23 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
CN110753557B (zh) * | 2017-03-22 | 2024-03-22 | 神济昌华(北京)生物科技有限公司 | Trim72通过泛素化fus蛋白突变体作为als的潜在治疗性靶标 |
AU2018261790A1 (en) | 2017-05-05 | 2019-11-28 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (ALS) |
JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
CN109609614B (zh) * | 2017-09-30 | 2022-07-15 | 首都医科大学附属北京胸科医院 | 检测trim2、trim4、trim32和/或trim46基因或蛋白产品的用途 |
EP3697908A1 (en) | 2017-10-16 | 2020-08-26 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
EP3697905A1 (en) | 2017-10-16 | 2020-08-26 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
CN108018303A (zh) * | 2017-12-20 | 2018-05-11 | 江苏浩欧博生物医药股份有限公司 | 一种人Ro52重组蛋白的制备方法 |
EP3765077A4 (en) * | 2018-03-14 | 2022-01-05 | Technion Research & Development Foundation Limited | PROGNOSTIC BIOMARKER IN CANCER |
US11147815B2 (en) | 2018-08-21 | 2021-10-19 | Synkrino Biotherapeutics, Inc. | Compositions and methods for treating diseases associated with uncontrolled inflammatory responses |
US20210369731A1 (en) * | 2018-10-09 | 2021-12-02 | The Regents Of The University Of California | Covalent targeting of e3 ligases |
EP3966227A1 (en) * | 2019-05-07 | 2022-03-16 | Voyager Therapeutics, Inc. | Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation |
CN110302383A (zh) * | 2019-07-29 | 2019-10-08 | 深圳先进技术研究院 | Trim11基因和蛋白靶点以及抑制剂在乳腺癌中的用途 |
CN110669791B (zh) * | 2019-10-29 | 2020-08-04 | 成都益安博生物技术有限公司 | 一种提高细胞抗体表达量的方法 |
KR102114880B1 (ko) * | 2020-01-15 | 2020-05-26 | 서울대학교병원 | 코돈 최적화된 TIF1γ 폴리뉴클레오티드를 포함하는 재조합 벡터 및 이의 용도 |
WO2022165313A1 (en) | 2021-02-01 | 2022-08-04 | Regenxbio Inc. | Gene therapy for neuronal ceroid lipofuscinoses |
CN113292658B (zh) * | 2021-04-17 | 2023-02-28 | 复旦大学 | 一种融合蛋白及其在靶向降解细胞内蛋白中的应用 |
CN113651879A (zh) * | 2021-08-18 | 2021-11-16 | 武汉华美生物工程有限公司 | 一种trim21全长蛋白的制备方法及应用 |
CN117159747A (zh) * | 2023-08-30 | 2023-12-05 | 暨南大学 | 一种亨廷顿舞蹈症的药物及其制备方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010027182A1 (en) | 1998-05-29 | 2001-10-04 | Huda Y. Zoghbi | Chaperone suppression of ataxin-1 aggregation and altered subcellular proteasome localization imply protein misfilind in sca1 |
WO2001090342A2 (en) | 2000-05-22 | 2001-11-29 | Johns Hopkins University | Genetic engineering of vascular grafts to resist disease |
US20040235733A1 (en) | 2003-02-27 | 2004-11-25 | Steffan Joan S. | Methods and reagents for reducing polyglutamine toxicity |
US20050215562A1 (en) * | 2003-06-23 | 2005-09-29 | Patrick Tremblay | Methods for treating protein aggregation disorders |
WO2005081911A2 (en) * | 2004-02-25 | 2005-09-09 | Dana-Farber Cancer Institute, Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF HIV INFECTION USING TRIM5α |
US20140056873A1 (en) | 2004-06-10 | 2014-02-27 | University Of Leicester | Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation |
NZ563003A (en) | 2005-04-27 | 2011-03-31 | Univ Florida | Use of a farnesyl transferase inhibitor to enhance autophagic protein degradation in protein conformation disorders |
EP1870107A1 (en) | 2006-06-23 | 2007-12-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of inducer of promyelocytic leukemia protein (PML) for treating polyglutamine expansion neurodegenerative diseases |
US7785857B2 (en) | 2006-08-31 | 2010-08-31 | Saint Louis University | Protein C variant |
AU2010204723A1 (en) * | 2009-01-14 | 2011-08-18 | The Salk Institute For Biological Studies | Methods for screening and compounds that protect against amyloid diseases |
CA2833908C (en) * | 2010-04-23 | 2021-02-09 | University Of Massachusetts | Cns targeting aav vectors and methods of use thereof |
GB201012410D0 (en) * | 2010-07-23 | 2010-09-08 | Medical Res Council | Intracellular immunity |
US9060507B2 (en) | 2010-09-01 | 2015-06-23 | Perfusion Fluid Technologies Inc | Perfusion solution |
CN103127492A (zh) * | 2011-11-23 | 2013-06-05 | 中国科学院上海巴斯德研究所 | 一种抗丙型肝炎病毒的蛋白及其用途 |
US10253099B2 (en) * | 2012-12-05 | 2019-04-09 | Ruprecht-Karls-Universität Heidelberg | Conjugates of proteins and multivalent cell-penetrating peptides and their uses |
WO2016054554A1 (en) * | 2014-10-03 | 2016-04-07 | University Of Massachusetts | Heterologous targeting peptide grafted aavs |
-
2016
- 2016-05-27 EP EP16804142.4A patent/EP3302706A4/en active Pending
- 2016-05-27 IL IL255912A patent/IL255912B2/en unknown
- 2016-05-27 WO PCT/US2016/034751 patent/WO2016196328A1/en active Application Filing
- 2016-05-27 MX MX2017015373A patent/MX2017015373A/es unknown
- 2016-05-27 RU RU2021134920A patent/RU2021134920A/ru unknown
- 2016-05-27 JP JP2017561811A patent/JP7011467B2/ja active Active
- 2016-05-27 KR KR1020177037891A patent/KR20180011276A/ko not_active IP Right Cessation
- 2016-05-27 CA CA2987057A patent/CA2987057A1/en active Pending
- 2016-05-27 IL IL302965A patent/IL302965A/en unknown
- 2016-05-27 RU RU2017144862A patent/RU2761564C9/ru active
- 2016-05-27 AU AU2016271635A patent/AU2016271635B2/en active Active
- 2016-05-27 SG SG10202011833TA patent/SG10202011833TA/en unknown
- 2016-05-27 CN CN201680044063.4A patent/CN108271364A/zh active Pending
- 2016-05-27 US US15/577,915 patent/US11542500B2/en active Active
- 2016-05-27 BR BR112017025574A patent/BR112017025574A2/pt active Search and Examination
-
2017
- 2017-11-28 ZA ZA2017/08067A patent/ZA201708067B/en unknown
- 2017-11-29 MX MX2021014954A patent/MX2021014954A/es unknown
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2018
- 2018-09-19 HK HK18112082.4A patent/HK1252757A1/zh unknown
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2021
- 2021-09-24 JP JP2021155978A patent/JP2022000459A/ja active Pending
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2022
- 2022-02-02 AU AU2022200673A patent/AU2022200673A1/en active Pending
- 2022-11-21 US US18/057,308 patent/US20230313190A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2022200673A1 (en) | 2022-02-24 |
RU2761564C9 (ru) | 2022-03-17 |
JP7011467B2 (ja) | 2022-02-10 |
JP2018521014A (ja) | 2018-08-02 |
CA2987057A1 (en) | 2016-12-08 |
SG10202011833TA (en) | 2021-01-28 |
EP3302706A1 (en) | 2018-04-11 |
AU2016271635A1 (en) | 2018-01-25 |
US20230313190A1 (en) | 2023-10-05 |
ZA201708067B (en) | 2018-11-28 |
KR20180011276A (ko) | 2018-01-31 |
RU2017144862A3 (es) | 2019-11-20 |
IL255912A (en) | 2018-01-31 |
RU2761564C2 (ru) | 2021-12-10 |
JP2022000459A (ja) | 2022-01-04 |
MX2021014954A (es) | 2022-01-31 |
BR112017025574A2 (pt) | 2018-08-14 |
WO2016196328A1 (en) | 2016-12-08 |
HK1252757A1 (zh) | 2019-05-31 |
CN108271364A (zh) | 2018-07-10 |
IL255912B1 (en) | 2023-06-01 |
AU2016271635B2 (en) | 2021-11-04 |
IL302965A (en) | 2023-07-01 |
IL255912B2 (en) | 2023-10-01 |
US20180163202A1 (en) | 2018-06-14 |
RU2021134920A (ru) | 2022-04-15 |
RU2017144862A (ru) | 2019-07-02 |
US11542500B2 (en) | 2023-01-03 |
EP3302706A4 (en) | 2019-05-08 |
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