MX2016007054A - Produccion microbiana de aminas grasas. - Google Patents

Produccion microbiana de aminas grasas.

Info

Publication number
MX2016007054A
MX2016007054A MX2016007054A MX2016007054A MX2016007054A MX 2016007054 A MX2016007054 A MX 2016007054A MX 2016007054 A MX2016007054 A MX 2016007054A MX 2016007054 A MX2016007054 A MX 2016007054A MX 2016007054 A MX2016007054 A MX 2016007054A
Authority
MX
Mexico
Prior art keywords
fatty amines
microbial production
host cells
production
employing
Prior art date
Application number
MX2016007054A
Other languages
English (en)
Inventor
B Del Cardayre Stephen
G Hom Louis
Original Assignee
Reg Life Sciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reg Life Sciences Llc filed Critical Reg Life Sciences Llc
Publication of MX2016007054A publication Critical patent/MX2016007054A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01042—Hexadecanal dehydrogenase (acylating) (1.2.1.42), i.e. fatty acyl-CoA reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/09—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with a copper protein as acceptor (1.4.9)
    • C12Y104/09001—Methylamine dehydrogenase (amicyanin) (1.4.9.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01019—4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01082—Putrescine aminotransferase (2.6.1.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/08—Transferases for other substituted phosphate groups (2.7.8)
    • C12Y207/08007—Holo-[acyl-carrier-protein] synthase (2.7.8.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01003—Long-chain-fatty-acid-CoA ligase (6.2.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La descripción se refiere a microorganismos recombinantes para la producción de aminas grasas y derivados de las mismas. Se contemplan además células hospederas recombinantes cultivadas así como métodos para producir aminas grasas al emplear estas células hospederas.
MX2016007054A 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas. MX2016007054A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361912184P 2013-12-05 2013-12-05
PCT/US2014/068950 WO2015085271A1 (en) 2013-12-05 2014-12-05 Microbial production of fatty amines

Publications (1)

Publication Number Publication Date
MX2016007054A true MX2016007054A (es) 2016-09-06

Family

ID=52350294

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016007054A MX2016007054A (es) 2013-12-05 2014-12-05 Produccion microbiana de aminas grasas.
MX2020001357A MX2020001357A (es) 2013-12-05 2016-05-31 Produccion microbiana de aminas grasas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2020001357A MX2020001357A (es) 2013-12-05 2016-05-31 Produccion microbiana de aminas grasas.

Country Status (12)

Country Link
US (2) US10900057B2 (es)
EP (3) EP3647430B1 (es)
JP (3) JP6553610B2 (es)
KR (2) KR102321813B1 (es)
CN (2) CN105874075B (es)
AU (1) AU2014360086B2 (es)
BR (2) BR112016012371B1 (es)
CA (2) CA3114049C (es)
ES (2) ES2932529T3 (es)
MX (2) MX2016007054A (es)
MY (1) MY180645A (es)
WO (1) WO2015085271A1 (es)

Families Citing this family (7)

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Publication number Priority date Publication date Assignee Title
US11339384B2 (en) 2017-04-03 2022-05-24 Genomatica, Inc. Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives
WO2022155554A1 (en) * 2021-01-17 2022-07-21 Genomatica, Inc. Methods and compositions for making amide compounds
JPWO2022209763A1 (es) 2021-03-30 2022-10-06
US20240158764A1 (en) 2021-03-30 2024-05-16 Asahi Kasei Kabushiki Kaisha Recombinant polypeptide having acyl-coa compound reducing activity
EP4353814A1 (en) 2021-05-19 2024-04-17 Asahi Kasei Kabushiki Kaisha Recombinant microorganism having diamine producing ability and method for manufacturing diamine
CN114437979B (zh) * 2022-02-14 2023-10-24 恒臻(无锡)生物科技有限公司 可降解芥酸酰胺的节杆菌及其获取方法、培养方法和应用
WO2023178211A1 (en) 2022-03-16 2023-09-21 Genomatica, Inc. Microorganisms and methods for production of fatty acid derivatives with reduced levels of byproducts

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CA3041892C (en) * 2008-10-28 2022-03-15 REG Life Sciences, LLC Methods for producing a fatty alcohol in a host cell
MX368526B (es) * 2008-12-23 2019-10-07 Reg Life Sciences Llc Metodos y composiciones relacionados con tioesterasa enzima.
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KR20190127993A (ko) 2011-08-19 2019-11-13 게노마티카 인코포레이티드 2,4-펜타디에노에이트, 부타디엔, 프로필렌, 1,3-부탄디올 및 관련 알코올을 생합성하기 위한 미생물과 방법
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AU2013246405B2 (en) * 2012-04-13 2018-08-02 Genomatica, Inc. Microbial production of alkanolamides and amidoamines and uses thereof

Also Published As

Publication number Publication date
CN105874075A (zh) 2016-08-17
CA2932017A1 (en) 2015-06-11
EP3077526A1 (en) 2016-10-12
CN111471723A (zh) 2020-07-31
CA2932017C (en) 2021-05-25
BR122020001956B1 (pt) 2023-03-14
JP2021177785A (ja) 2021-11-18
JP2019205440A (ja) 2019-12-05
ES2932529T3 (es) 2023-01-20
JP7152365B2 (ja) 2022-10-12
US11814660B2 (en) 2023-11-14
MX2020001357A (es) 2020-03-20
AU2014360086A1 (en) 2016-07-14
KR102321813B1 (ko) 2021-11-04
BR112016012371B1 (pt) 2023-03-28
EP3077526B8 (en) 2020-01-08
EP3647430A1 (en) 2020-05-06
CN105874075B (zh) 2020-10-23
US20210164002A1 (en) 2021-06-03
ES2772774T3 (es) 2020-07-08
CA3114049C (en) 2023-06-13
CA3114049A1 (en) 2015-06-11
EP3077526B1 (en) 2019-11-20
US20190032097A1 (en) 2019-01-31
JP6553610B2 (ja) 2019-07-31
EP3647430B1 (en) 2022-10-26
MY180645A (en) 2020-12-04
KR20210134820A (ko) 2021-11-10
AU2014360086B2 (en) 2018-04-19
EP4163383A1 (en) 2023-04-12
BR112016012371A2 (pt) 2017-09-26
JP2016538870A (ja) 2016-12-15
KR20160095053A (ko) 2016-08-10
WO2015085271A1 (en) 2015-06-11
US10900057B2 (en) 2021-01-26

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Owner name: GENOMATICA, INC.