MX2015008847A - Composiciones inmunogenicas de virus de influenza y usos de las mismas. - Google Patents
Composiciones inmunogenicas de virus de influenza y usos de las mismas.Info
- Publication number
- MX2015008847A MX2015008847A MX2015008847A MX2015008847A MX2015008847A MX 2015008847 A MX2015008847 A MX 2015008847A MX 2015008847 A MX2015008847 A MX 2015008847A MX 2015008847 A MX2015008847 A MX 2015008847A MX 2015008847 A MX2015008847 A MX 2015008847A
- Authority
- MX
- Mexico
- Prior art keywords
- influenza virus
- rna
- epitope
- immunogenic compositions
- component
- Prior art date
Links
- 241000712461 unidentified influenza virus Species 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16311—Influenzavirus C, i.e. influenza C virus
- C12N2760/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Animal Husbandry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361751077P | 2013-01-10 | 2013-01-10 | |
| PCT/EP2014/050414 WO2014108515A1 (en) | 2013-01-10 | 2014-01-10 | Influenza virus immunogenic compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015008847A true MX2015008847A (es) | 2015-10-30 |
Family
ID=49956176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015008847A MX2015008847A (es) | 2013-01-10 | 2014-01-10 | Composiciones inmunogenicas de virus de influenza y usos de las mismas. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20140193484A1 (enExample) |
| EP (1) | EP2943221A1 (enExample) |
| JP (2) | JP2016506416A (enExample) |
| CN (2) | CN109045294A (enExample) |
| AU (2) | AU2014204826A1 (enExample) |
| CA (1) | CA2897752A1 (enExample) |
| HK (1) | HK1214962A1 (enExample) |
| MX (1) | MX2015008847A (enExample) |
| RU (1) | RU2015132962A (enExample) |
| WO (1) | WO2014108515A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9708373B2 (en) | 2010-03-30 | 2017-07-18 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccine and uses thereof |
| JP2013537518A (ja) | 2010-07-06 | 2013-10-03 | ノバルティス アーゲー | RNA送達に有利なpKa値を有する脂質を含むリポソーム |
| DK3243526T3 (da) | 2010-07-06 | 2020-02-17 | Glaxosmithkline Biologicals Sa | Levering af rna til at udløse flere immunsignalveje |
| CA2804492A1 (en) | 2010-07-06 | 2012-01-12 | Novartis Ag | Immunisation of large mammals with low doses of rna |
| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| FI4066857T3 (fi) | 2010-08-31 | 2023-03-20 | Glaxosmithkline Biologicals Sa | Pegyloituja liposomeja immunogeeniä koodaavan rna:n kuljettamiseksi |
| EP4108671B1 (en) | 2010-10-01 | 2024-11-20 | ModernaTX, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| RU2597974C2 (ru) | 2010-10-11 | 2016-09-20 | Новартис Аг | Платформы доставки антигенов |
| JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
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| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| WO2013043729A1 (en) | 2011-09-20 | 2013-03-28 | Mount Sinai School Of Medicine | Influenza virus vaccines and uses thereof |
| PL2791160T3 (pl) | 2011-12-16 | 2022-06-20 | Modernatx, Inc. | Kompozycje zmodyfikowanego mrna |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
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| EP2934581B1 (en) | 2012-12-18 | 2022-09-14 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
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| WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
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| WO2016118937A1 (en) | 2015-01-23 | 2016-07-28 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccination regimens |
| RU2742993C2 (ru) | 2015-05-15 | 2021-02-12 | Куревак Аг | РЕЖИМЫ ПРАЙМ-БУСТ, ВКЛЮЧАЮЩИЕ ВВЕДЕНИЕ ПО МЕНЬШЕЙ МЕРЕ ОДНОЙ КОНСТРУКЦИИ мРНК |
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| CA2804492A1 (en) * | 2010-07-06 | 2012-01-12 | Novartis Ag | Immunisation of large mammals with low doses of rna |
| EP4180057A1 (en) | 2010-07-06 | 2023-05-17 | GlaxoSmithKline Biologicals S.A. | Virion-like delivery particles for self-replicating rna molecules |
| JP2013537518A (ja) | 2010-07-06 | 2013-10-03 | ノバルティス アーゲー | RNA送達に有利なpKa値を有する脂質を含むリポソーム |
| US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| DK3243526T3 (da) * | 2010-07-06 | 2020-02-17 | Glaxosmithkline Biologicals Sa | Levering af rna til at udløse flere immunsignalveje |
| US20130189351A1 (en) * | 2010-08-31 | 2013-07-25 | Novartis Ag | Lipids suitable for liposomal delivery of protein coding rna |
| FI4043040T3 (fi) | 2010-08-31 | 2023-04-04 | Glaxosmithkline Biologicals Sa | Pieniä liposomeja immunogeeniä koodaavan rna:n toimittamiseksi |
| FI4066857T3 (fi) * | 2010-08-31 | 2023-03-20 | Glaxosmithkline Biologicals Sa | Pegyloituja liposomeja immunogeeniä koodaavan rna:n kuljettamiseksi |
| US20130164289A1 (en) * | 2010-09-09 | 2013-06-27 | Virginia Commonwealth University | Human cytomegalovirus vaccine |
| RU2597974C2 (ru) * | 2010-10-11 | 2016-09-20 | Новартис Аг | Платформы доставки антигенов |
| SI2667892T1 (sl) * | 2011-01-26 | 2019-05-31 | Glaxosmithkline Biologicals Sa | Imunizacijski režim proti RSV |
| PT2707385T (pt) * | 2011-05-13 | 2017-12-19 | Glaxosmithkline Biologicals Sa | Antigénios de f de rsv pré-fusão |
| JP2014520807A (ja) * | 2011-07-06 | 2014-08-25 | ノバルティス アーゲー | 免疫原性組成物およびその使用 |
| CA2840913C (en) | 2011-07-06 | 2020-01-21 | Novartis Ag | Oil-in-water emulsions that contain nucleic acids |
| WO2013006838A1 (en) * | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| EP2729124B1 (en) | 2011-07-06 | 2018-10-24 | GlaxoSmithKline Biologicals SA | Cationic oil-in-water emulsions |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| EP2750707B1 (en) | 2011-08-31 | 2018-10-24 | GlaxoSmithKline Biologicals SA | Pegylated liposomes for delivery of immunogen-encoding rna |
| CN104105504A (zh) * | 2011-10-11 | 2014-10-15 | 诺华股份有限公司 | 重组多顺反子核酸分子 |
| WO2013054199A2 (en) * | 2011-10-12 | 2013-04-18 | Novartis Ag | Cmv antigens and uses thereof |
| US9504747B2 (en) * | 2013-03-08 | 2016-11-29 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
-
2014
- 2014-01-10 AU AU2014204826A patent/AU2014204826A1/en not_active Abandoned
- 2014-01-10 CA CA2897752A patent/CA2897752A1/en not_active Abandoned
- 2014-01-10 WO PCT/EP2014/050414 patent/WO2014108515A1/en not_active Ceased
- 2014-01-10 US US14/152,397 patent/US20140193484A1/en not_active Abandoned
- 2014-01-10 CN CN201811056155.1A patent/CN109045294A/zh active Pending
- 2014-01-10 MX MX2015008847A patent/MX2015008847A/es unknown
- 2014-01-10 RU RU2015132962A patent/RU2015132962A/ru not_active Application Discontinuation
- 2014-01-10 JP JP2015552058A patent/JP2016506416A/ja active Pending
- 2014-01-10 CN CN201480004387.6A patent/CN104902925A/zh active Pending
- 2014-01-10 EP EP14700356.0A patent/EP2943221A1/en not_active Withdrawn
- 2014-01-10 HK HK16102971.1A patent/HK1214962A1/zh unknown
-
2017
- 2017-11-29 JP JP2017229215A patent/JP2018035195A/ja active Pending
-
2018
- 2018-11-13 AU AU2018260983A patent/AU2018260983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018260983A1 (en) | 2018-12-06 |
| JP2016506416A (ja) | 2016-03-03 |
| CN109045294A (zh) | 2018-12-21 |
| CA2897752A1 (en) | 2014-07-17 |
| JP2018035195A (ja) | 2018-03-08 |
| US20140193484A1 (en) | 2014-07-10 |
| HK1214962A1 (zh) | 2016-08-12 |
| AU2014204826A1 (en) | 2015-07-09 |
| RU2015132962A (ru) | 2017-02-14 |
| EP2943221A1 (en) | 2015-11-18 |
| WO2014108515A1 (en) | 2014-07-17 |
| CN104902925A (zh) | 2015-09-09 |
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