MX2015005891A - Formas polimórficas de suvorexant. - Google Patents
Formas polimórficas de suvorexant.Info
- Publication number
- MX2015005891A MX2015005891A MX2015005891A MX2015005891A MX2015005891A MX 2015005891 A MX2015005891 A MX 2015005891A MX 2015005891 A MX2015005891 A MX 2015005891A MX 2015005891 A MX2015005891 A MX 2015005891A MX 2015005891 A MX2015005891 A MX 2015005891A
- Authority
- MX
- Mexico
- Prior art keywords
- suvoroxant
- polymorphic forms
- suvorexant
- amorphous
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invención se relaciona con la forma cristalina de suvorexant, con la forma amorfa de suvorexant, con la dispersión de sólidos amorfos de suvorexant, con procesos para su preparación y con formas de dosificación farmacéutica de éstas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN4742CH2012 | 2012-11-12 | ||
IN5322CH2012 | 2012-12-19 | ||
PCT/IB2013/060080 WO2014072961A2 (en) | 2012-11-12 | 2013-11-12 | Polymorphic forms of suvoroxant |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015005891A true MX2015005891A (es) | 2015-12-09 |
Family
ID=50685273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015005891A MX2015005891A (es) | 2012-11-12 | 2013-11-12 | Formas polimórficas de suvorexant. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20160272627A1 (es) |
EP (1) | EP2917187A2 (es) |
JP (1) | JP2015536975A (es) |
KR (1) | KR20150097486A (es) |
CN (1) | CN104918920A (es) |
AU (1) | AU2013343027A1 (es) |
CA (1) | CA2890949A1 (es) |
IL (1) | IL238744A0 (es) |
MX (1) | MX2015005891A (es) |
WO (1) | WO2014072961A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2699358C2 (ru) | 2012-05-31 | 2019-09-05 | Мерк Шарп И Доум Корп. | Составы твердых дозированных лекарственных форм антагониста орексинового рецептора |
EP3131895A2 (en) * | 2014-04-17 | 2017-02-22 | Sandoz AG | Solid dispersion comprising an orexin receptor antagonist |
WO2015164160A1 (en) * | 2014-04-21 | 2015-10-29 | Merck Sharp & Dohme Corp. | Pharmaceutical salts of an orexin receptor antagonist |
WO2015180060A1 (zh) * | 2014-05-28 | 2015-12-03 | 杭州普晒医药科技有限公司 | 一种二氮杂环庚烷化合物的盐及其晶型与无定型物 |
CN104502499B (zh) * | 2014-12-10 | 2016-04-20 | 广东东阳光药业有限公司 | 一种异构体的高效液相检测方法 |
CN104569255B (zh) * | 2014-12-15 | 2016-04-20 | 广东东阳光药业有限公司 | 一种用HPLC测定Suvorexant中间体的方法 |
CZ201587A3 (cs) | 2015-02-10 | 2016-08-17 | Zentiva, K.S. | Amorfní pevná forma suvorexantu s kyselinou sírovou |
WO2017001499A1 (en) * | 2015-06-30 | 2017-01-05 | Hexal Ag | Liquid composition comprising suvorexant |
WO2017072264A1 (en) * | 2015-10-29 | 2017-05-04 | Hexal Ag | Solid composition comprising suvorexant |
CN107202855B (zh) * | 2016-03-17 | 2020-08-11 | 广东东阳光药业有限公司 | 一种用hplc测定苏沃雷生及其中间体的方法 |
CN110818701B (zh) * | 2018-08-13 | 2023-01-17 | 扬子江药业集团有限公司 | 一种苏沃雷生的精制方法 |
CN109651913A (zh) * | 2019-01-15 | 2019-04-19 | 湖南康瑞涂料科技有限公司 | 一种水基涂料组合物 |
CN114344269B (zh) * | 2021-12-28 | 2023-11-03 | 北京鑫开元医药科技有限公司 | 一种苏沃雷生片及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA100974C2 (ru) * | 2006-12-01 | 2013-02-25 | Мерк Шарп Энд Доме Корп. | Соединения замещенных диазепанов как антагонисты орексиновых рецепторов |
PE20081229A1 (es) * | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
US9108959B2 (en) * | 2011-03-03 | 2015-08-18 | Merck Sharp & Dohme Corp. | Process for the preparation of an orexin receptor antagonist |
-
2013
- 2013-11-12 WO PCT/IB2013/060080 patent/WO2014072961A2/en active Application Filing
- 2013-11-12 MX MX2015005891A patent/MX2015005891A/es unknown
- 2013-11-12 AU AU2013343027A patent/AU2013343027A1/en not_active Abandoned
- 2013-11-12 CA CA2890949A patent/CA2890949A1/en not_active Abandoned
- 2013-11-12 US US14/442,269 patent/US20160272627A1/en not_active Abandoned
- 2013-11-12 JP JP2015541292A patent/JP2015536975A/ja active Pending
- 2013-11-12 EP EP13852476.4A patent/EP2917187A2/en not_active Withdrawn
- 2013-11-12 KR KR1020157015142A patent/KR20150097486A/ko not_active Application Discontinuation
- 2013-11-12 CN CN201380070078.4A patent/CN104918920A/zh active Pending
-
2015
- 2015-05-11 IL IL238744A patent/IL238744A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL238744A0 (en) | 2015-06-30 |
WO2014072961A2 (en) | 2014-05-15 |
CA2890949A1 (en) | 2014-05-15 |
CN104918920A (zh) | 2015-09-16 |
AU2013343027A1 (en) | 2015-06-18 |
EP2917187A2 (en) | 2015-09-16 |
US20160272627A1 (en) | 2016-09-22 |
WO2014072961A3 (en) | 2014-07-03 |
KR20150097486A (ko) | 2015-08-26 |
JP2015536975A (ja) | 2015-12-24 |
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