SI3309158T1 - Rivaroksaban kristalne oblike K in postopek njegove priprave - Google Patents

Rivaroksaban kristalne oblike K in postopek njegove priprave

Info

Publication number
SI3309158T1
SI3309158T1 SI201331997T SI201331997T SI3309158T1 SI 3309158 T1 SI3309158 T1 SI 3309158T1 SI 201331997 T SI201331997 T SI 201331997T SI 201331997 T SI201331997 T SI 201331997T SI 3309158 T1 SI3309158 T1 SI 3309158T1
Authority
SI
Slovenia
Prior art keywords
rivaroxaban
preparation
crystalline form
crystalline
Prior art date
Application number
SI201331997T
Other languages
English (en)
Inventor
Silvo Zupancic
Primoz Benkic
Original Assignee
Krka, Tovarna Zdravil D.D., Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49876637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3309158(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Krka, Tovarna Zdravil D.D., Novo Mesto filed Critical Krka, Tovarna Zdravil D.D., Novo Mesto
Publication of SI3309158T1 publication Critical patent/SI3309158T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
SI201331997T 2012-12-21 2013-12-19 Rivaroksaban kristalne oblike K in postopek njegove priprave SI3309158T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI201200386 2012-12-21
EP17186150.3A EP3309158B1 (en) 2012-12-21 2013-12-19 Crystalline form k of rivaroxaban and process for its preparation

Publications (1)

Publication Number Publication Date
SI3309158T1 true SI3309158T1 (sl) 2023-12-29

Family

ID=49876637

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201330837T SI2935255T1 (sl) 2012-12-21 2013-12-19 Postopek za pripravo rivaroksabana
SI201331997T SI3309158T1 (sl) 2012-12-21 2013-12-19 Rivaroksaban kristalne oblike K in postopek njegove priprave

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI201330837T SI2935255T1 (sl) 2012-12-21 2013-12-19 Postopek za pripravo rivaroksabana

Country Status (8)

Country Link
EP (2) EP2935255B1 (sl)
ES (1) ES2647607T3 (sl)
HR (1) HRP20171707T1 (sl)
HU (1) HUE037188T2 (sl)
PL (1) PL2935255T3 (sl)
PT (1) PT2935255T (sl)
SI (2) SI2935255T1 (sl)
WO (1) WO2014096214A1 (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016030669A1 (en) * 2014-08-25 2016-03-03 Cipla Limited Process for the preparation of rivaroxaban
CN105503849B (zh) * 2014-09-26 2019-10-08 重庆华邦胜凯制药有限公司 一种制备小粒度利伐沙班原料药的方法
WO2016062828A1 (en) * 2014-10-22 2016-04-28 Zaklady Farmaceutyczne Polpharma S.A Process for preparing a polymorph of rivaroxaban
CN105777738A (zh) * 2014-12-16 2016-07-20 南京生命能科技开发有限公司 一种利伐沙班原料药及其制备方法
CN109422720B (zh) * 2017-08-22 2021-07-20 新发药业有限公司 一种低成本、高纯度5-氯噻吩-2-甲酰氯的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) * 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE102004002044A1 (de) 2004-01-15 2005-08-04 Bayer Healthcare Ag Herstellverfahren
US8188270B2 (en) 2005-10-04 2012-05-29 Bayer Schering Pharma Aktiengesellschaft Polymorphous form of 5-chloro-N-({(5S)-2-oxo-3[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
DE102008028071A1 (de) 2008-06-12 2009-12-17 Bayer Schering Pharma Aktiengesellschaft Neue Cokristall-Verbindung von Rivaroxaban und Malonsäure
US20100168111A1 (en) 2008-12-31 2010-07-01 Apotex Pharmachem Inc. Polymorphic form of 5 chloro n {[(5s) 2 oxo 3 [4 (3 oxomorpholin 4 yl)phenyl]oxa-zolidin 5 yl]-methyl}thiophene 2 carboxamide
WO2010146179A2 (en) 2009-06-18 2010-12-23 Krka, Tovarna Zdravil, D.D., Novo Mesto Solid pharmaceutical composition comprising rivaroxaban
ES2905760T3 (es) 2009-07-31 2022-04-12 Krka D D Novo Mesto Procedimientos para la cristalización del rivaroxabán
EP2404920A1 (en) 2010-07-06 2012-01-11 Sandoz AG Crystalline form of Rivaroxaban dihydrate
US20130253187A1 (en) 2010-09-14 2013-09-26 Medichem, S.A. Process for Determining the Suitability for Distribution of a Batch of Thiophene-2-Carboxamide Derivative
CZ2010714A3 (cs) 2010-09-30 2012-04-11 Farmak, A. S. Zpusob výroby 2-({(5S)-2-oxo-3-[4-(3-oxo-4-morfolinyl)fenyl]-1,3oxazolidin-5-yl}methyl)-1H-isoindol-1,3(2H)-dionu ve vysoké optické cistote
US9221771B2 (en) * 2011-04-11 2015-12-29 Sandoz Ag Method for the preparation of substituted oxazolidinones
GEP20156397B (en) 2011-05-06 2015-11-10 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Process for the preparation of a rivaroxaban and intermediates formed in said process

Also Published As

Publication number Publication date
EP3309158A1 (en) 2018-04-18
HRP20171707T1 (hr) 2017-12-15
PT2935255T (pt) 2017-11-21
EP2935255A1 (en) 2015-10-28
PL2935255T3 (pl) 2018-01-31
EP2935255B1 (en) 2017-08-16
EP3309158B1 (en) 2022-03-16
HUE037188T2 (hu) 2018-08-28
ES2647607T3 (es) 2017-12-22
WO2014096214A1 (en) 2014-06-26
SI2935255T1 (sl) 2018-01-31

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