PL2935255T3 - Sposób wytwarzania rywaroksabanu - Google Patents

Sposób wytwarzania rywaroksabanu

Info

Publication number
PL2935255T3
PL2935255T3 PL13811529T PL13811529T PL2935255T3 PL 2935255 T3 PL2935255 T3 PL 2935255T3 PL 13811529 T PL13811529 T PL 13811529T PL 13811529 T PL13811529 T PL 13811529T PL 2935255 T3 PL2935255 T3 PL 2935255T3
Authority
PL
Poland
Prior art keywords
rivaroxaban
preparation
Prior art date
Application number
PL13811529T
Other languages
English (en)
Inventor
Silvo Zupancic
Primoz Benkic
Original Assignee
Farma Grs D O O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49876637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2935255(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Farma Grs D O O filed Critical Farma Grs D O O
Publication of PL2935255T3 publication Critical patent/PL2935255T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL13811529T 2012-12-21 2013-12-19 Sposób wytwarzania rywaroksabanu PL2935255T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201200386 2012-12-21
EP13811529.0A EP2935255B1 (en) 2012-12-21 2013-12-19 A process for preparation of rivaroxaban
PCT/EP2013/077431 WO2014096214A1 (en) 2012-12-21 2013-12-19 A process for preparation of rivaroxaban

Publications (1)

Publication Number Publication Date
PL2935255T3 true PL2935255T3 (pl) 2018-01-31

Family

ID=49876637

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13811529T PL2935255T3 (pl) 2012-12-21 2013-12-19 Sposób wytwarzania rywaroksabanu

Country Status (8)

Country Link
EP (2) EP2935255B1 (pl)
ES (1) ES2647607T3 (pl)
HR (1) HRP20171707T1 (pl)
HU (1) HUE037188T2 (pl)
PL (1) PL2935255T3 (pl)
PT (1) PT2935255T (pl)
SI (2) SI2935255T1 (pl)
WO (1) WO2014096214A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3186246A1 (en) * 2014-08-25 2017-07-05 Cipla Limited Process for the preparation of rivaroxaban
CN105503849B (zh) * 2014-09-26 2019-10-08 重庆华邦胜凯制药有限公司 一种制备小粒度利伐沙班原料药的方法
WO2016062828A1 (en) * 2014-10-22 2016-04-28 Zaklady Farmaceutyczne Polpharma S.A Process for preparing a polymorph of rivaroxaban
CN105777738A (zh) * 2014-12-16 2016-07-20 南京生命能科技开发有限公司 一种利伐沙班原料药及其制备方法
CN109422720B (zh) * 2017-08-22 2021-07-20 新发药业有限公司 一种低成本、高纯度5-氯噻吩-2-甲酰氯的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962924A1 (de) * 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
DE102004002044A1 (de) * 2004-01-15 2005-08-04 Bayer Healthcare Ag Herstellverfahren
AU2006299126B2 (en) 2005-10-04 2012-06-28 Bayer Intellectual Property Gmbh Novel polymorphous form and the amorphous form of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
DE102008028071A1 (de) 2008-06-12 2009-12-17 Bayer Schering Pharma Aktiengesellschaft Neue Cokristall-Verbindung von Rivaroxaban und Malonsäure
US20100168111A1 (en) 2008-12-31 2010-07-01 Apotex Pharmachem Inc. Polymorphic form of 5 chloro n {[(5s) 2 oxo 3 [4 (3 oxomorpholin 4 yl)phenyl]oxa-zolidin 5 yl]-methyl}thiophene 2 carboxamide
HUE031177T2 (hu) 2009-06-18 2017-07-28 Krka Tovarna Zdravil D D Novo Mesto Rivaroxabant tartalmazó szilárd gyógyszerkészítmény
SI2459555T1 (sl) 2009-07-31 2022-03-31 Krka, D.D., Novo Mesto Postopek kristalizacije rivaroksabana
EP2404920A1 (en) 2010-07-06 2012-01-11 Sandoz AG Crystalline form of Rivaroxaban dihydrate
US20130253187A1 (en) 2010-09-14 2013-09-26 Medichem, S.A. Process for Determining the Suitability for Distribution of a Batch of Thiophene-2-Carboxamide Derivative
CZ2010714A3 (cs) 2010-09-30 2012-04-11 Farmak, A. S. Zpusob výroby 2-({(5S)-2-oxo-3-[4-(3-oxo-4-morfolinyl)fenyl]-1,3oxazolidin-5-yl}methyl)-1H-isoindol-1,3(2H)-dionu ve vysoké optické cistote
EP2697209B1 (en) * 2011-04-11 2015-09-23 Sandoz AG Method for the preparation of substituted oxazolidinones
WO2012153155A1 (en) 2011-05-06 2012-11-15 Egis Gyógyszergyár Nyilvãnosan Müködö Részvény-Társaság Process for the preparation of a rivaroxaban and intermediates formed in said process

Also Published As

Publication number Publication date
WO2014096214A1 (en) 2014-06-26
PT2935255T (pt) 2017-11-21
HRP20171707T1 (hr) 2017-12-15
HUE037188T2 (hu) 2018-08-28
EP3309158A1 (en) 2018-04-18
EP2935255A1 (en) 2015-10-28
ES2647607T3 (es) 2017-12-22
SI3309158T1 (sl) 2023-12-29
SI2935255T1 (en) 2018-01-31
EP3309158B1 (en) 2022-03-16
EP2935255B1 (en) 2017-08-16

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