MX2014013646A - Agonistas del receptor v1a. - Google Patents
Agonistas del receptor v1a.Info
- Publication number
- MX2014013646A MX2014013646A MX2014013646A MX2014013646A MX2014013646A MX 2014013646 A MX2014013646 A MX 2014013646A MX 2014013646 A MX2014013646 A MX 2014013646A MX 2014013646 A MX2014013646 A MX 2014013646A MX 2014013646 A MX2014013646 A MX 2014013646A
- Authority
- MX
- Mexico
- Prior art keywords
- receptor agonists
- compounds
- hrs2
- cirrhosis
- complications
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polyurethanes Or Polyureas (AREA)
- Polyesters Or Polycarbonates (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
(ver Fórmula) Se describen compuestos de la fórmula (I), sales de los mismos y composiciones y usos de los mismos. Los compuestos son útiles como agonistas de vasopresina V1a, para el tratamiento de, por ejemplo, complicaciones de cirrosis, incluyendo peritonitis bacteriana, HRS2 y ascitis refractaria.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645558P | 2012-05-10 | 2012-05-10 | |
| PCT/US2013/040414 WO2013170077A2 (en) | 2012-05-10 | 2013-05-09 | V1a receptor agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014013646A true MX2014013646A (es) | 2015-03-03 |
| MX353864B MX353864B (es) | 2018-02-01 |
Family
ID=48652296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014013646A MX353864B (es) | 2012-05-10 | 2013-05-09 | Agonistas del receptor v1a. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9644000B2 (es) |
| EP (1) | EP2847210B1 (es) |
| JP (1) | JP6231554B2 (es) |
| KR (1) | KR102050356B1 (es) |
| CN (1) | CN104350065B (es) |
| AR (1) | AR091013A1 (es) |
| AU (1) | AU2013259393B2 (es) |
| BR (1) | BR112014027996B1 (es) |
| CA (1) | CA2871776C (es) |
| DK (1) | DK2847210T3 (es) |
| ES (1) | ES2571928T3 (es) |
| HK (1) | HK1205706A1 (es) |
| HR (1) | HRP20160468T1 (es) |
| HU (1) | HUE027519T2 (es) |
| IL (1) | IL235558A (es) |
| JO (1) | JO3109B1 (es) |
| MX (1) | MX353864B (es) |
| MY (1) | MY167248A (es) |
| NZ (1) | NZ701365A (es) |
| PH (1) | PH12014502510A1 (es) |
| PL (1) | PL2847210T3 (es) |
| RS (1) | RS54722B1 (es) |
| RU (1) | RU2634617C2 (es) |
| SA (1) | SA113340536B1 (es) |
| SG (1) | SG11201407400XA (es) |
| SI (1) | SI2847210T1 (es) |
| TW (1) | TWI632161B (es) |
| WO (1) | WO2013170077A2 (es) |
| ZA (1) | ZA201408172B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9388214B2 (en) | 2014-11-05 | 2016-07-12 | Ferring B.V. | V1A receptor agonists |
| JP2017014206A (ja) | 2015-06-30 | 2017-01-19 | ナノアンティバイオティクス，インコーポレイテッド | 腹水の治療 |
| PL3464336T3 (pl) | 2016-06-01 | 2022-05-16 | Athira Pharma, Inc. | Związki |
| CN109010795B (zh) * | 2018-09-12 | 2021-10-22 | 南京康舟医药科技有限公司 | 醋酸特利加压素注射液以及其制备方法 |
| IL299805A (en) * | 2020-07-17 | 2023-03-01 | Pharmain Corp | V1A receptor partial agonist and method of use |
| WO2023183339A1 (en) * | 2022-03-22 | 2023-09-28 | Ocelot Bio, Inc. | Selective vasopressin receptor agonist for end-stage liver disease |
| WO2024073451A1 (en) * | 2022-09-30 | 2024-04-04 | Ocelot Bio, Inc. | Mixed vasopressin receptor agonist-antagonist for treating end-stage liver disease and complications associated thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU32702A (sh) * | 1999-11-04 | 2005-06-10 | Ortho-Mcneil Pharmaceutical Inc. | Nepeptidni supstituisani benzotiazepini kao antagonisti vazopresina |
| EP1188443A1 (en) * | 2000-09-15 | 2002-03-20 | Ferring BV | Improved protocol for paracentesis |
| JO2937B1 (en) * | 2004-08-11 | 2016-03-15 | فيرينغ.بي.في | Tight muscles of the peptide vascular tensioner receptor |
| KR100974967B1 (ko) * | 2005-07-14 | 2010-08-09 | 에프. 호프만-라 로슈 아게 | Ｖ1ａ 수용체 길항물질로서의인돌-3-카본일-스피로-피페리딘 유도체 |
| BRPI0616618A2 (pt) * | 2005-09-28 | 2011-06-28 | Hoffmann La Roche | derivados de indol-3-il-carbonil-azaespiro como antagonistas de receptor de vasopressina |
| ES2566143T3 (es) * | 2006-02-13 | 2016-04-11 | Ferring B.V. | Uso de agonistas peptídicos de receptor de vasopresina |
| US7960336B2 (en) * | 2007-08-03 | 2011-06-14 | Pharmain Corporation | Composition for long-acting peptide analogs |
-
2013
- 2013-04-24 JO JOP/2013/0118A patent/JO3109B1/ar active
- 2013-04-30 TW TW102115416A patent/TWI632161B/zh active
- 2013-05-08 SA SA113340536A patent/SA113340536B1/ar unknown
- 2013-05-09 AU AU2013259393A patent/AU2013259393B2/en active Active
- 2013-05-09 ES ES13729826T patent/ES2571928T3/es active Active
- 2013-05-09 PL PL13729826T patent/PL2847210T3/pl unknown
- 2013-05-09 MX MX2014013646A patent/MX353864B/es active IP Right Grant
- 2013-05-09 SI SI201330175A patent/SI2847210T1/sl unknown
- 2013-05-09 US US14/400,282 patent/US9644000B2/en active Active
- 2013-05-09 JP JP2015511718A patent/JP6231554B2/ja active Active
- 2013-05-09 WO PCT/US2013/040414 patent/WO2013170077A2/en active Application Filing
- 2013-05-09 BR BR112014027996-9A patent/BR112014027996B1/pt active IP Right Grant
- 2013-05-09 DK DK13729826.1T patent/DK2847210T3/en active
- 2013-05-09 MY MYPI2014703280A patent/MY167248A/en unknown
- 2013-05-09 NZ NZ701365A patent/NZ701365A/en unknown
- 2013-05-09 HU HUE13729826A patent/HUE027519T2/en unknown
- 2013-05-09 SG SG11201407400XA patent/SG11201407400XA/en unknown
- 2013-05-09 EP EP13729826.1A patent/EP2847210B1/en active Active
- 2013-05-09 CA CA2871776A patent/CA2871776C/en active Active
- 2013-05-09 RS RS20160293A patent/RS54722B1/en unknown
- 2013-05-09 CN CN201380024444.2A patent/CN104350065B/zh active Active
- 2013-05-09 RU RU2014143941A patent/RU2634617C2/ru active
- 2013-05-09 KR KR1020147034501A patent/KR102050356B1/ko active IP Right Grant
- 2013-05-10 AR ARP130101626 patent/AR091013A1/es active IP Right Grant
-
2014
- 2014-11-06 IL IL235558A patent/IL235558A/en active IP Right Grant
- 2014-11-07 ZA ZA2014/08172A patent/ZA201408172B/en unknown
- 2014-11-10 PH PH12014502510A patent/PH12014502510A1/en unknown
-
2015
- 2015-10-09 HK HK15108881.8A patent/HK1205706A1/zh unknown
-
2016
- 2016-05-03 HR HRP20160468TT patent/HRP20160468T1/hr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12014502510B1 (en) | V1a receptor agonists | |
| PH12014502169A1 (en) | N-cyclylamides as nematicides | |
| GEP20217235B (en) | Processes for preparing quinoline compounds and pharmaceutical compositions containing such compounds | |
| PH12014502697A1 (en) | New diazaspirocycloalkane and azaspirocycloalkane | |
| GB201106829D0 (en) | Heterocyclic compounds | |
| IN2014MN02574A (es) | ||
| AU2011232516A8 (en) | Chemical compounds | |
| AU2012213775A8 (en) | 7-azaindole derivatives | |
| MY164776A (en) | Heterocyclic compound | |
| MX2014014531A (es) | Derivados de aminoquinazolina y piridopirimidina. | |
| MX2011007998A (es) | Nuevos herbicidas. | |
| MY161132A (en) | Novel herbicides | |
| MX2011007932A (es) | Herbicidas nuevos. | |
| MY169267A (en) | New aryl-quinoline derivatives | |
| MX353190B (es) | Derivados de isoquinolina y naftiridina. | |
| SG10201900541QA (en) | Derivatives of xanthone compounds | |
| MX2013000009A (es) | Procedimiento de preparacion de la sal de l-arginina de perindoprilo. | |
| HK1124842A1 (en) | Methods of preparing imidazole-based compounds | |
| TN2011000355A1 (en) | Novel microbiocides | |
| GB201107985D0 (en) | Process | |
| NZ702736A (en) | Processes and reagents for making diaryliodonium salts | |
| MX2012007837A (es) | Derivados de oxazolopirimidina 2, 5 - sustituidos. | |
| MX2013009386A (es) | Nuevos compuestos de azaespirodecanona. | |
| IN2012DN01223A (es) | ||
| MX2016000487A (es) | Piridina-2-carboxamidas como nematicidas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |