MX2014012957A - Microaguja y disposicion de microagujas. - Google Patents

Microaguja y disposicion de microagujas.

Info

Publication number
MX2014012957A
MX2014012957A MX2014012957A MX2014012957A MX2014012957A MX 2014012957 A MX2014012957 A MX 2014012957A MX 2014012957 A MX2014012957 A MX 2014012957A MX 2014012957 A MX2014012957 A MX 2014012957A MX 2014012957 A MX2014012957 A MX 2014012957A
Authority
MX
Mexico
Prior art keywords
microneedle
distal end
section
shaft section
drug
Prior art date
Application number
MX2014012957A
Other languages
English (en)
Inventor
Kiyotsuna Toyohara
Taishi Tanaka
Takashi Oda
Koichi Masaoka
Katsunori Kobayashi
Masaki Ishibashi
Hidetoshi Hamamoto
Kazuteru Kohno
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of MX2014012957A publication Critical patent/MX2014012957A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micromachines (AREA)

Abstract

El propósito de la presente invención es proporcionar una microaguja y una disposición de microagujas capaces de soportar no solamente un fármaco sino también un estabilizador o un espesante en grandes cantidades, y ofrecer propiedades de punción favorables. La presente invención es una microaguja para administrar un fármaco transcutáneamente, la microaguja comprende una sección de punta, una sección de árbol y una sección base; (i) el ángulo del ápice de punta (a) es de 15 a 60°; (ii) el diámetro de punta (D0) está en el intervalo de 1 a 20 µm; (iii) el área (A3) de la superficie superior de la sección base es más grande que el área (A2) de la superficie de fondo de la sección de árbol; (iv) se satisfacen las fórmulas (1) y (2) H/D4 = 3 (1) (H es la altura general, y D4 es el diámetro de la superficie de fondo de la sección base) y ß = 90 - 0.5a (2) (ß es el ángulo formado entre la superficie lateral de la sección de árbol y la superficie superior de la sección base, y a es el ángulo del ápice de punta); y (v) una composición sólida que contiene el fármaco se fija a la superficie lateral de la sección de árbol y satisface la fórmula (5) : 10° = ? = 60° (5) (? es el ángulo formado por las líneas tangentes que conectan el ápice de la sección superior y la superficie de la composición sólida fija a la superficie lateral de la sección de árbol).
MX2014012957A 2012-04-25 2013-04-24 Microaguja y disposicion de microagujas. MX2014012957A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012099489 2012-04-25
PCT/JP2013/062735 WO2013162053A1 (ja) 2012-04-25 2013-04-24 マイクロニードルおよびマイクロニードルアレイ

Publications (1)

Publication Number Publication Date
MX2014012957A true MX2014012957A (es) 2015-02-05

Family

ID=49483341

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014012957A MX2014012957A (es) 2012-04-25 2013-04-24 Microaguja y disposicion de microagujas.

Country Status (13)

Country Link
US (1) US9974935B2 (es)
EP (1) EP2842595B1 (es)
JP (1) JP5439633B1 (es)
KR (1) KR20150003745A (es)
CN (1) CN104321105B (es)
AU (1) AU2013253306A1 (es)
BR (1) BR112014026570B1 (es)
CA (1) CA2871575A1 (es)
ES (1) ES2730735T3 (es)
HK (1) HK1205024A1 (es)
MX (1) MX2014012957A (es)
RU (1) RU2014147308A (es)
WO (1) WO2013162053A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013309944A1 (en) * 2012-08-30 2015-03-05 Medrx Co., Ltd. Microneedle array coated with drug composition
BR112015005073B1 (pt) * 2012-09-13 2021-06-01 Amir Avraham Aplicador configurado para a administração de uma composição de melhoria de pele para uma pele e/ou subcútis de um sujeito, uso de um, microagulha e método para manufaturar uma microagulha
JP2015109963A (ja) * 2013-10-30 2015-06-18 帝人株式会社 薬剤でコーティングされたマイクロニードルアレイの製造方法
JP6023752B2 (ja) * 2014-06-10 2016-11-09 日本写真印刷株式会社 マイクロニードルシート及び経皮投与用貼付剤
JP5852280B1 (ja) 2015-03-23 2016-02-03 コスメディ製薬株式会社 マイクロニードルおよびその製造
PL3284506T3 (pl) 2015-04-13 2021-10-25 Lg Household & Health Care Ltd. Rozpuszczalna mikroigła zawierająca składnik do kontroli uwalniania neuroprzekaźników
KR102203633B1 (ko) * 2015-04-14 2021-01-15 주식회사 엘지생활건강 칼슘채널 차단제 전달용 용해성 미세바늘
US20180369136A1 (en) * 2015-12-28 2018-12-27 North Carolina State University Devices and methods for transdermal treatment of basal cell carcinoma
CN108430565B (zh) 2015-12-28 2021-07-20 (株)安道德玛 用于经皮吸收的微结构体及其制备方法
US11266344B2 (en) 2016-09-21 2022-03-08 Samsung Electronics Co., Ltd. Method for measuring skin condition and electronic device therefor
KR102012226B1 (ko) * 2017-09-08 2019-08-20 주식회사 에스스킨 마이크로니들 템플레이트 및 이를 이용하여 제조되는 마이크로니들
CN111836662A (zh) 2018-03-13 2020-10-27 美德阿利克斯株式会社 粘合构件和微针贴剂
CN111939452A (zh) * 2019-05-15 2020-11-17 微邦科技股份有限公司 微针结构及其生物可降解微针
TWI687247B (zh) 2019-05-15 2020-03-11 微邦科技股份有限公司 微針結構及其生物可降解微針
WO2023042889A1 (ja) * 2021-09-15 2023-03-23 コスメディ製薬株式会社 薬剤を塗布したマイクロニードルアレイ
CN114487060A (zh) * 2021-12-30 2022-05-13 北京宝理泰科技有限公司 一种用于检测葡萄糖的聚合物微针装置
WO2023229290A1 (ko) * 2022-05-24 2023-11-30 에스피투티엑스주식회사 마이크로니들 및 이의 제조 방법
WO2024011075A2 (en) * 2022-07-05 2024-01-11 StimuSIL, Inc. Dermal light delivery device for light therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101224257B1 (ko) 2004-11-18 2013-01-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 어레이를 코팅하기 위한 마스킹 방법
CA2612005C (en) * 2005-06-17 2013-10-29 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
WO2007012114A1 (en) * 2005-07-25 2007-02-01 Nanotechnology Victoria Pty Ltd Microarray device
JP2007130030A (ja) 2005-11-08 2007-05-31 Toray Ind Inc マイクロニードル、マイクロニードル集合体及びその製造方法
JP2007190112A (ja) 2006-01-18 2007-08-02 Toray Ind Inc マイクロニードル
JP4908893B2 (ja) 2006-03-30 2012-04-04 久光製薬株式会社 医薬物運搬用器具とその製造方法及び医薬物運搬用器具製造用金型の製造方法
JP4723436B2 (ja) 2006-08-28 2011-07-13 株式会社日本製鋼所 溶融樹脂の塗布による成形体の製造装置
JP2008142183A (ja) 2006-12-07 2008-06-26 Fujifilm Corp マイクロニードルシート及びその製造方法
JP4521492B2 (ja) 2008-07-01 2010-08-11 コスメディ製薬株式会社 マイクロニードルアレイ及びその製造方法
JP2010069270A (ja) 2008-09-17 2010-04-02 Yoshiichi Tobinaga 機能剤投与デバイス、その製造方法及び製造装置
JP2010069720A (ja) * 2008-09-18 2010-04-02 Riso Kagaku Corp 携帯端末データの印刷装置
US8834423B2 (en) * 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
EP2338557A1 (en) 2009-12-23 2011-06-29 Debiotech S.A. Soluble microneedle
EP2575845B1 (en) 2010-05-28 2017-02-15 3M Innovative Properties Company Aqueous formulations for coating microneedle arrays

Also Published As

Publication number Publication date
RU2014147308A (ru) 2016-06-10
EP2842595A1 (en) 2015-03-04
BR112014026570A2 (pt) 2018-09-18
JPWO2013162053A1 (ja) 2015-12-24
WO2013162053A1 (ja) 2013-10-31
ES2730735T3 (es) 2019-11-12
KR20150003745A (ko) 2015-01-09
BR112014026570B1 (pt) 2021-06-29
HK1205024A1 (en) 2015-12-11
CN104321105A (zh) 2015-01-28
JP5439633B1 (ja) 2014-03-12
EP2842595A4 (en) 2015-12-09
EP2842595B1 (en) 2019-03-20
CN104321105B (zh) 2016-11-23
US9974935B2 (en) 2018-05-22
AU2013253306A1 (en) 2014-11-13
CA2871575A1 (en) 2013-10-31
US20150094648A1 (en) 2015-04-02

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