MX2014007128A - Metodo de floculacion. - Google Patents

Metodo de floculacion.

Info

Publication number
MX2014007128A
MX2014007128A MX2014007128A MX2014007128A MX2014007128A MX 2014007128 A MX2014007128 A MX 2014007128A MX 2014007128 A MX2014007128 A MX 2014007128A MX 2014007128 A MX2014007128 A MX 2014007128A MX 2014007128 A MX2014007128 A MX 2014007128A
Authority
MX
Mexico
Prior art keywords
flocculation method
polymers
ionic
cell culture
mammalian cell
Prior art date
Application number
MX2014007128A
Other languages
English (en)
Other versions
MX353959B (es
Inventor
Thomas M Mcnerney
Krista Petty
Anne C Thomas
Xiaoyang Zhao
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2014007128A publication Critical patent/MX2014007128A/es
Publication of MX353959B publication Critical patent/MX353959B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Abstract

La presente invención se relaciona a un método para cosechar proteínas recombinantes del fluido de cultivo celular de mamífero. El método hace uso de los polímeros catiónicos, polímeros no iónicos y tensoactivos no iónicos.
MX2014007128A 2011-12-15 2012-12-14 Metodo de floculacion. MX353959B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161576303P 2011-12-15 2011-12-15
PCT/US2012/069916 WO2013090820A1 (en) 2011-12-15 2012-12-14 Flocculation method

Publications (2)

Publication Number Publication Date
MX2014007128A true MX2014007128A (es) 2015-03-23
MX353959B MX353959B (es) 2018-02-07

Family

ID=47559662

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007128A MX353959B (es) 2011-12-15 2012-12-14 Metodo de floculacion.

Country Status (18)

Country Link
US (2) US9371554B2 (es)
EP (1) EP2791319B1 (es)
JP (4) JP2015504659A (es)
KR (5) KR20140103320A (es)
CN (2) CN113150060A (es)
AR (1) AR089231A1 (es)
AU (4) AU2012351926A1 (es)
BR (1) BR112014014116A2 (es)
CA (1) CA2859197C (es)
CL (1) CL2014001564A1 (es)
EA (1) EA201491144A1 (es)
HK (1) HK1199057A1 (es)
IL (2) IL233028B (es)
MX (1) MX353959B (es)
SG (1) SG11201403258VA (es)
TW (1) TWI576144B (es)
WO (1) WO2013090820A1 (es)
ZA (1) ZA201404351B (es)

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AR089231A1 (es) * 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
TWI776235B (zh) * 2014-06-09 2022-09-01 美商健臻公司 種子罐培養法(seed train processes)及其用途
FI20165282A (fi) 2016-04-01 2017-10-02 Kemira Oyj Menetelmä ja järjestelmä koaguloinnin ja/tai flokkuloinnin optimoimiseksi veden käsittelyprosessissa
US10927145B2 (en) * 2016-06-15 2021-02-23 Agency For Science, Technology And Research Method of enhancing the performance of chromatography methods for purification of proteins
JP2021536241A (ja) * 2018-08-30 2021-12-27 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 核酸を検出する方法
HUP1900112A1 (hu) 2019-04-04 2020-10-28 Richter Gedeon Nyrt Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelõzõ flokkulálás alkalmazásával
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants
CN111068367A (zh) * 2019-12-17 2020-04-28 青岛宝和信生物科技有限公司 植物/中药提取液及水处理连续自动化絮凝及分离工艺
GB2590721A (en) 2019-12-31 2021-07-07 Inst Jozef Stefan Controlled aggregation of cells
BR112023005111A2 (pt) 2020-09-22 2023-04-18 Basf Se Método para recuperar uma proteína de interesse de um caldo de fermentação bacteriana, e, uso de pelo menos um floculante
WO2024059235A2 (en) 2022-09-16 2024-03-21 Amgen Inc. A method for harvesting products from perfusion cultures

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AR089231A1 (es) * 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion

Also Published As

Publication number Publication date
KR20190137944A (ko) 2019-12-11
AR089231A1 (es) 2014-08-06
SG11201403258VA (en) 2014-07-30
KR20220084192A (ko) 2022-06-21
CL2014001564A1 (es) 2015-01-16
US20150004646A1 (en) 2015-01-01
CN104245922B (zh) 2021-04-30
HK1199057A1 (en) 2015-06-19
CN113150060A (zh) 2021-07-23
AU2012351926A2 (en) 2014-08-07
AU2018204547A1 (en) 2018-07-12
CN104245922A (zh) 2014-12-24
KR20230172040A (ko) 2023-12-21
IL233028B (en) 2018-12-31
US9371554B2 (en) 2016-06-21
KR20140103320A (ko) 2014-08-26
EA201491144A1 (ru) 2014-09-30
MX353959B (es) 2018-02-07
JP2023099117A (ja) 2023-07-11
JP2022000046A (ja) 2022-01-04
KR20210095723A (ko) 2021-08-02
TWI576144B (zh) 2017-04-01
AU2018204547B2 (en) 2020-10-22
IL263674A (en) 2019-01-31
JP2015504659A (ja) 2015-02-16
JP6998853B2 (ja) 2022-01-18
ZA201404351B (en) 2015-05-27
IL233028A0 (en) 2014-07-31
EP2791319A1 (en) 2014-10-22
AU2023219874A1 (en) 2023-09-07
AU2012351926A1 (en) 2014-07-10
JP2019022515A (ja) 2019-02-14
WO2013090820A1 (en) 2013-06-20
CA2859197C (en) 2017-01-03
JP7274547B2 (ja) 2023-05-16
AU2020267147A1 (en) 2020-12-03
AU2020267147B2 (en) 2023-05-25
EP2791319B1 (en) 2016-04-27
US20160297850A1 (en) 2016-10-13
TW201341030A (zh) 2013-10-16
BR112014014116A2 (pt) 2017-06-13
CA2859197A1 (en) 2013-06-20

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