MX2014002787A - Organismos eucarioticos y metodos para producir 1, 3 -butanodiol. - Google Patents

Organismos eucarioticos y metodos para producir 1, 3 -butanodiol.

Info

Publication number
MX2014002787A
MX2014002787A MX2014002787A MX2014002787A MX2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A MX 2014002787 A MX2014002787 A MX 2014002787A
Authority
MX
Mexico
Prior art keywords
butanediol
methods
eukaryotic organisms
producing
organisms
Prior art date
Application number
MX2014002787A
Other languages
English (en)
Spanish (es)
Inventor
Mark J Burk
Anthony P Burgard
Robin E Osterhout
Priti Pharkya
Jingyi Li
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2014002787A publication Critical patent/MX2014002787A/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/16Dicarboxylic acids and dihydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/32Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MX2014002787A 2011-09-08 2012-09-07 Organismos eucarioticos y metodos para producir 1, 3 -butanodiol. MX2014002787A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161532492P 2011-09-08 2011-09-08
US201161541951P 2011-09-30 2011-09-30
US201161558959P 2011-11-11 2011-11-11
US201261649039P 2012-05-18 2012-05-18
US201261655355P 2012-06-04 2012-06-04
PCT/US2012/054152 WO2013036764A1 (en) 2011-09-08 2012-09-07 Eukaryotic organisms and methods for producing 1,3-butanediol

Publications (1)

Publication Number Publication Date
MX2014002787A true MX2014002787A (es) 2014-12-08

Family

ID=47830417

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002787A MX2014002787A (es) 2011-09-08 2012-09-07 Organismos eucarioticos y metodos para producir 1, 3 -butanodiol.

Country Status (11)

Country Link
US (2) US20130066035A1 (cg-RX-API-DMAC7.html)
EP (1) EP2753699A4 (cg-RX-API-DMAC7.html)
KR (1) KR20140058691A (cg-RX-API-DMAC7.html)
CN (1) CN103917651A (cg-RX-API-DMAC7.html)
BR (1) BR112014005352A2 (cg-RX-API-DMAC7.html)
CA (1) CA2848064A1 (cg-RX-API-DMAC7.html)
IN (1) IN2014CN02584A (cg-RX-API-DMAC7.html)
MX (1) MX2014002787A (cg-RX-API-DMAC7.html)
PH (1) PH12014500513A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201400466TA (cg-RX-API-DMAC7.html)
WO (1) WO2013036764A1 (cg-RX-API-DMAC7.html)

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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
EP2899270A4 (en) * 2012-09-24 2016-07-20 Showa Denko Kk PROCESS FOR PREPARING BUTANEDIOL
BR112015021885B1 (pt) 2013-03-15 2021-08-17 Genomatica, Inc Processo para purificação de 1,4-butanodiol (1,4-bdo)
US20160040172A1 (en) 2013-03-15 2016-02-11 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US10066245B2 (en) 2013-06-14 2018-09-04 Technical University Of Denmark Microbial production of 3-hydroxypropionic acid
US10704050B2 (en) 2013-10-18 2020-07-07 Biopetrolia Ab Engineering of acetyl-CoA metabolism in yeast
WO2015077752A1 (en) 2013-11-25 2015-05-28 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
EP3077501B1 (en) 2013-12-03 2021-07-28 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
CN113416686B (zh) 2013-12-27 2024-08-06 基因组股份公司 具有增加的碳通量效率的方法和生物
US20170298363A1 (en) 2014-09-18 2017-10-19 Genomatica, Inc Non-natural microbial organisms with improved energetic efficiency
ES2981536T3 (es) 2014-12-12 2024-10-09 Versalis Spa Proceso para la producción de 1,3-butadieno a partir de 1,3-butanodiol
JP6789229B2 (ja) 2015-02-23 2020-11-25 ヴェルサリス ソシエタ ペル アチオニ 含酸素化合物の脱水方法
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
BR112017025554B1 (pt) 2015-05-30 2024-03-12 Genomatica, Inc. Composição, e, método para produzir um polímero, resina ou artigo de fabricação
CN104988162B (zh) * 2015-06-08 2020-03-17 天津大学 辅因子再生模块在增强次级代谢产物在微生物中合成的应用
CN104988168A (zh) * 2015-06-08 2015-10-21 天津大学 乙酰辅酶a增强模块在增强7-脱氢胆甾醇在微生物中合成的应用
KR101704212B1 (ko) 2015-06-12 2017-02-08 씨제이제일제당 (주) 젖산을 생산하는 미생물 및 이를 이용한 젖산 제조 방법
WO2017006183A1 (en) * 2015-07-08 2017-01-12 Conradie Alex Van Eck Methods and host cells for enhancing production of 1,3-butanediol
US10626423B2 (en) * 2015-07-21 2020-04-21 The Governing Council Of The University Of Toronto Methods and microorganisms for the production of 1,3-butanediol
CN108603179B (zh) * 2015-10-06 2022-02-08 帝斯曼知识产权资产管理有限公司 发酵产物生产增加的真核细胞
US11441128B2 (en) 2015-10-30 2022-09-13 Genomatica, Inc. Methanol dehydrogenase fusion proteins
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR20240033193A (ko) 2017-03-31 2024-03-12 게노마티카 인코포레이티드 알데하이드 데하이드로게나제 변이체 및 사용 방법
CN118064458A (zh) 2017-03-31 2024-05-24 基因组股份公司 3-羟基丁酰基-CoA脱氢酶变体以及使用方法
WO2019011945A1 (en) * 2017-07-11 2019-01-17 Adisseo France S.A.S. IMPROVED YEAST PRODUCING METABOLITE
CA3069708A1 (en) * 2017-07-13 2019-01-17 Radici Chimica S.P.A. Biological methods for preparing terpenes
MX2020000366A (es) * 2017-07-13 2020-08-17 Radici Chimica S P A Métodos biológicos para la modificación de flujo de carbono celular.
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
JP2021528977A (ja) 2018-06-26 2021-10-28 ジェノマティカ, インコーポレイテッド グリセルアルデヒド3−リン酸(g3p)を3−ホスホグリセリン酸(3pg)に変換する酵素および/またはフルクトース−1,6−ビスホスファターゼを有する組換え微生物(合成または増強されたメチロトロフィーを有するものを含む)
HUE065469T2 (hu) 2018-09-21 2024-06-28 Versalis Spa Eljárás bio-1,3-butándiol tisztítására fermentációs lébõl
EP3856896A1 (en) 2018-09-26 2021-08-04 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
US20210332377A1 (en) * 2018-10-12 2021-10-28 Yield10 Bioscience, Inc. Genetically engineered plants that express a quinone-utilizing malate dehydrogenase
US11390889B2 (en) 2018-10-30 2022-07-19 Green Earth Institute Co., Ltd. Method for manufacturing 1,3-propanediol
CN110564662B (zh) * 2019-09-30 2022-03-25 南京农业大学 一种整合型高效表达乙醛脱氢酶枯草杆菌的构建方法
CN115873881A (zh) * 2021-09-30 2023-03-31 北京化工大学 一种产1,3-丁二醇的基因工程菌及其应用
CN117701489B (zh) * 2024-02-05 2024-05-10 北京绿色康成生物技术有限公司 一种提高大肠杆菌生产1,3-丁二醇的方法

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Also Published As

Publication number Publication date
CA2848064A1 (en) 2013-03-14
EP2753699A1 (en) 2014-07-16
AU2012304428B2 (en) 2016-03-17
PH12014500513A1 (en) 2014-05-12
KR20140058691A (ko) 2014-05-14
BR112014005352A2 (pt) 2017-03-28
AU2012304428A1 (en) 2013-05-02
IN2014CN02584A (cg-RX-API-DMAC7.html) 2015-08-07
US20130066035A1 (en) 2013-03-14
WO2013036764A1 (en) 2013-03-14
US20170247709A1 (en) 2017-08-31
CN103917651A (zh) 2014-07-09
SG11201400466TA (en) 2014-04-28
EP2753699A4 (en) 2015-08-19

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