MX2013015308A - Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso. - Google Patents
Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso.Info
- Publication number
- MX2013015308A MX2013015308A MX2013015308A MX2013015308A MX2013015308A MX 2013015308 A MX2013015308 A MX 2013015308A MX 2013015308 A MX2013015308 A MX 2013015308A MX 2013015308 A MX2013015308 A MX 2013015308A MX 2013015308 A MX2013015308 A MX 2013015308A
- Authority
- MX
- Mexico
- Prior art keywords
- purification
- preparation
- processes
- proteasome inhibitors
- proteasome
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 229940079156 Proteasome inhibitor Drugs 0.000 title 1
- 239000003207 proteasome inhibitor Substances 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161499962P | 2011-06-22 | 2011-06-22 | |
| PCT/US2012/043485 WO2012177835A1 (en) | 2011-06-22 | 2012-06-21 | Proteasome inhibitors and processes for their preparation, purification and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013015308A true MX2013015308A (es) | 2014-05-20 |
Family
ID=46395746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013015308A MX2013015308A (es) | 2011-06-22 | 2012-06-21 | Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140121182A1 (enExample) |
| EP (1) | EP2723751A1 (enExample) |
| JP (1) | JP5944986B2 (enExample) |
| CA (1) | CA2833775A1 (enExample) |
| MX (1) | MX2013015308A (enExample) |
| WO (1) | WO2012177835A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160058886A (ko) * | 2013-10-03 | 2016-05-25 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 전신 홍반성 낭창 및/또는 낭창성 신염의 예방 또는 치료 방법 |
| US9546928B2 (en) | 2014-05-30 | 2017-01-17 | General Electric Company | Methods for producing strain sensors on turbine components |
| US10415964B2 (en) * | 2014-05-30 | 2019-09-17 | General Electric Company | Methods for producing passive strain indicator on turbine components |
| MA41505A (fr) * | 2015-02-11 | 2017-12-19 | Millennium Pharm Inc | Nouvelle forme cristalline d'un inhibiteur de protéasome |
| CZ2015233A3 (cs) | 2015-04-03 | 2016-10-12 | Zentiva, K.S. | Způsob přípravy Ixazomib citrátu |
| CZ2015253A3 (cs) | 2015-04-15 | 2016-10-26 | Zentiva, K.S. | Nové formy Ixazomib citrátu |
| US10144761B2 (en) | 2015-06-19 | 2018-12-04 | Hanlin Scientific Inc. | Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis |
| CN106608883A (zh) * | 2015-10-21 | 2017-05-03 | 北京大学 | 蛋白酶体抑制剂mln9708的合成方法 |
| CN106986884A (zh) * | 2016-01-20 | 2017-07-28 | 成都贝斯凯瑞生物科技有限公司 | 一种高效的高纯度含硼化合物制备方法 |
| CN105732683B (zh) * | 2016-03-25 | 2018-10-16 | 南京林业大学 | 一类羧酸与α氨基酸组成的二肽硼酸及其酯类化合物、制备方法及其用途 |
| CZ2016204A3 (cs) | 2016-04-08 | 2017-11-01 | Zentiva, K.S. | Formulace Ixazomib citrátu formy 3 |
| CN107400142B (zh) * | 2016-05-19 | 2019-11-19 | 成都奥璟生物科技有限公司 | 一种硼酸和硼酸酯类化合物及其应用 |
| CN108440583B (zh) * | 2017-01-23 | 2020-12-04 | 成都奥璟生物科技有限公司 | 一种新的硼酸衍生物及其药物组合物 |
| US11414437B2 (en) | 2017-07-28 | 2022-08-16 | Chengdu Origin Biotechnology Limited Company | Borate compound, and synthesis method therefor and uses thereof |
| CN112513052B (zh) * | 2018-08-02 | 2022-12-16 | 正大天晴药业集团股份有限公司 | 氮杂环丁烷衍生物的硼酸酯 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| US7576206B2 (en) | 2003-08-14 | 2009-08-18 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| PL4008721T3 (pl) | 2004-03-30 | 2024-05-13 | Millennium Pharmaceuticals, Inc. | Synteza związków estrów i kwasów boronowych |
| US7442830B1 (en) | 2007-08-06 | 2008-10-28 | Millenium Pharmaceuticals, Inc. | Proteasome inhibitors |
| GEP20125599B (en) * | 2007-08-06 | 2012-08-10 | Millennium Pharm Inc | Proteasome inhibitors |
| BR122014008753A2 (pt) | 2008-06-17 | 2015-12-29 | Millennium Pharm Inc | compostos de éster boronato e composições farmacêuticas dos mesmos |
| EP2238973A1 (en) * | 2009-04-07 | 2010-10-13 | Cephalon France | Lyophilized preparations of proteasome inhibitors |
-
2012
- 2012-06-21 MX MX2013015308A patent/MX2013015308A/es unknown
- 2012-06-21 JP JP2014517144A patent/JP5944986B2/ja not_active Expired - Fee Related
- 2012-06-21 CA CA2833775A patent/CA2833775A1/en not_active Abandoned
- 2012-06-21 WO PCT/US2012/043485 patent/WO2012177835A1/en not_active Ceased
- 2012-06-21 EP EP12730349.3A patent/EP2723751A1/en not_active Withdrawn
- 2012-06-21 US US14/127,511 patent/US20140121182A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012177835A1 (en) | 2012-12-27 |
| JP5944986B2 (ja) | 2016-07-05 |
| EP2723751A1 (en) | 2014-04-30 |
| CA2833775A1 (en) | 2012-12-27 |
| JP2014520155A (ja) | 2014-08-21 |
| US20140121182A1 (en) | 2014-05-01 |
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