MX2013012187A - Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico. - Google Patents

Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico.

Info

Publication number
MX2013012187A
MX2013012187A MX2013012187A MX2013012187A MX2013012187A MX 2013012187 A MX2013012187 A MX 2013012187A MX 2013012187 A MX2013012187 A MX 2013012187A MX 2013012187 A MX2013012187 A MX 2013012187A MX 2013012187 A MX2013012187 A MX 2013012187A
Authority
MX
Mexico
Prior art keywords
cyclic depsipeptide
suspension type
topical formulations
type topical
compositions
Prior art date
Application number
MX2013012187A
Other languages
English (en)
Other versions
MX338156B (es
Inventor
Claire Haug
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46148908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013012187(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2013012187A publication Critical patent/MX2013012187A/es
Publication of MX338156B publication Critical patent/MX338156B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a novedosas composiciones farmacéuticas tópicas en donde el agente activo es un depsipéptido cíclico de la fórmula (II): (ver Fórmula) y a métodos para la elaboración de estas composiciones. La solicitud da a conocer en particular ungüentos hidrofóbicos que comprenden una base hidrofóbica y un agente de consistencia, de preferencia miristato de isopropilo.
MX2013012187A 2011-04-20 2012-04-18 Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico. MX338156B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161477297P 2011-04-20 2011-04-20
PCT/IB2012/051946 WO2012143868A1 (en) 2011-04-20 2012-04-18 Suspension type topical formulations comprising cyclic depsipeptide

Publications (2)

Publication Number Publication Date
MX2013012187A true MX2013012187A (es) 2013-11-04
MX338156B MX338156B (es) 2016-04-05

Family

ID=46148908

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013012187A MX338156B (es) 2011-04-20 2012-04-18 Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico.

Country Status (21)

Country Link
US (2) US8680054B2 (es)
EP (1) EP2699231B1 (es)
JP (1) JP5906304B2 (es)
KR (1) KR101612170B1 (es)
CN (1) CN103476396B (es)
AR (1) AR086109A1 (es)
AU (1) AU2012245960B2 (es)
BR (1) BR112013026698A2 (es)
CA (1) CA2833326A1 (es)
CL (1) CL2013003036A1 (es)
EA (1) EA201391555A1 (es)
ES (1) ES2651639T3 (es)
GT (1) GT201300257A (es)
IL (1) IL228863A0 (es)
MA (1) MA35158B1 (es)
MX (1) MX338156B (es)
PE (1) PE20141068A1 (es)
SG (1) SG11201402441WA (es)
TN (1) TN2013000386A1 (es)
TW (1) TW201247218A (es)
WO (1) WO2012143868A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2183273B1 (en) 2007-08-17 2017-04-05 Novartis AG Cyclic depsipeptides
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
CN108888590A (zh) * 2018-08-06 2018-11-27 江苏知原药业有限公司 包含他克莫司的混悬类型的局部制剂
WO2021178834A1 (en) * 2020-03-06 2021-09-10 LifeMax Laboratories, Inc. Topical pharmaceutical formulations of a cyclic depsipeptide

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3043252C2 (de) 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
DE4421113A1 (de) 1994-06-16 1995-12-21 Biotechnolog Forschung Gmbh Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung
DE19828043A1 (de) 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
JP2000154198A (ja) 1998-11-20 2000-06-06 Nisshin Flour Milling Co Ltd 環状デプシペプチドの固相合成方法及びその中間体
JP2001131085A (ja) * 1999-08-25 2001-05-15 Saitama Daiichi Seiyaku Kk 経皮・経粘膜吸収用の医薬組成物
GB0108234D0 (en) 2001-04-02 2001-05-23 Pharma Mar Sa Process for producing trunkamide A compounds
US20040110228A1 (en) 2002-04-01 2004-06-10 Mcalpine Shelli R. Combinatorial organic synthesis of unique biologically active compounds
KR101099409B1 (ko) 2003-06-06 2011-12-27 아렉시스 악티에볼라그 피부 상태 또는 암 치료를 위한 ｓｃｃｅ 저해제로서의융합된 헤테로사이클 화합물의 용도
GB0322140D0 (en) * 2003-09-22 2003-10-22 Pfizer Ltd Combinations
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
WO2005075667A1 (en) 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
AU2007220042A1 (en) 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Identification and use of novopeptides for the treatment of cancer
EP2183273B1 (en) * 2007-08-17 2017-04-05 Novartis AG Cyclic depsipeptides
EP2183270B1 (en) 2007-08-17 2014-12-17 Novartis AG Use of cyclic depsipeptides to inhibit kallikrein 7
DE102007052391A1 (de) 2007-10-31 2009-05-07 Henkel Ag & Co. Kgaa Mattwachs
JP2010241784A (ja) * 2008-06-19 2010-10-28 Mitsubishi Tanabe Pharma Corp 経皮投与製剤
US20110112121A1 (en) * 2009-07-06 2011-05-12 Joerg Berghausen Pharmaceutical Compositions and Solid Forms
US20120064013A1 (en) 2010-02-03 2012-03-15 David Marcos Foamable topical composition
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 ＴＮＦ－α와 ＴＷＥＡＫ 이중 길항제
US20120064136A1 (en) 2010-09-10 2012-03-15 Nanobio Corporation Anti-aging and wrinkle treatment methods using nanoemulsion compositions
ES2720648T3 (es) 2011-01-24 2019-07-23 Anterios Inc Composiciones de nanopartículas
WO2012103038A2 (en) 2011-01-24 2012-08-02 Anterios, Inc. Nanoparticle compositions, formulations thereof, and uses therefor
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates

Also Published As

Publication number Publication date
CA2833326A1 (en) 2012-10-26
EP2699231B1 (en) 2017-09-13
JP5906304B2 (ja) 2016-04-20
AU2012245960A1 (en) 2013-10-17
US20120270796A1 (en) 2012-10-25
PE20141068A1 (es) 2014-09-04
AR086109A1 (es) 2013-11-20
TN2013000386A1 (en) 2015-01-20
KR20130133295A (ko) 2013-12-06
ES2651639T3 (es) 2018-01-29
SG11201402441WA (en) 2014-09-26
IL228863A0 (en) 2013-12-31
MX338156B (es) 2016-04-05
EP2699231A1 (en) 2014-02-26
CL2013003036A1 (es) 2014-04-04
TW201247218A (en) 2012-12-01
EA201391555A1 (ru) 2014-11-28
US8680054B2 (en) 2014-03-25
US20140162959A1 (en) 2014-06-12
US9114110B2 (en) 2015-08-25
CN103476396B (zh) 2015-08-05
CN103476396A (zh) 2013-12-25
MA35158B1 (fr) 2014-06-02
JP2014512377A (ja) 2014-05-22
AU2012245960B2 (en) 2014-09-25
KR101612170B1 (ko) 2016-04-12
BR112013026698A2 (pt) 2016-12-27
GT201300257A (es) 2015-02-19
NZ615551A (en) 2015-08-28
WO2012143868A1 (en) 2012-10-26

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