MX2013012184A - Composiciones formadoras de gel in situ. - Google Patents

Composiciones formadoras de gel in situ.

Info

Publication number
MX2013012184A
MX2013012184A MX2013012184A MX2013012184A MX2013012184A MX 2013012184 A MX2013012184 A MX 2013012184A MX 2013012184 A MX2013012184 A MX 2013012184A MX 2013012184 A MX2013012184 A MX 2013012184A MX 2013012184 A MX2013012184 A MX 2013012184A
Authority
MX
Mexico
Prior art keywords
forming compositions
gel forming
situ gel
situ
sprayable
Prior art date
Application number
MX2013012184A
Other languages
English (en)
Other versions
MX340323B (es
Inventor
David M Gravett
George Y Daniloff
He Pingren
Original Assignee
Carbylan Biosurgery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46028170&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013012184(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Carbylan Biosurgery Inc filed Critical Carbylan Biosurgery Inc
Publication of MX2013012184A publication Critical patent/MX2013012184A/es
Publication of MX340323B publication Critical patent/MX340323B/es

Links

Classifications

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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
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Abstract

La presente solicitud proporciona composiciones basadas en ácido hialurónico atomizables de gelación rápida, kits, métodos relacionados, formulaciones precursoras, y usos de estas.
MX2013012184A 2011-04-20 2012-04-18 Composiciones formadoras de gel in situ. MX340323B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161477563P 2011-04-20 2011-04-20
PCT/US2012/034133 WO2012145439A1 (en) 2011-04-20 2012-04-18 In-situ gel forming compositions

Publications (2)

Publication Number Publication Date
MX2013012184A true MX2013012184A (es) 2014-05-27
MX340323B MX340323B (es) 2016-07-05

Family

ID=46028170

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013012184A MX340323B (es) 2011-04-20 2012-04-18 Composiciones formadoras de gel in situ.

Country Status (13)

Country Link
US (2) US9492383B2 (es)
EP (1) EP2699274B1 (es)
JP (1) JP5998201B2 (es)
KR (1) KR20140023372A (es)
CN (1) CN103732264B (es)
AU (1) AU2012245517B2 (es)
CA (1) CA2833739A1 (es)
DK (1) DK2699274T3 (es)
ES (1) ES2537411T3 (es)
HK (1) HK1195265A1 (es)
MX (1) MX340323B (es)
PT (1) PT2699274E (es)
WO (1) WO2012145439A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592251B2 (en) 2011-06-16 2017-03-14 The Hong Kong University Of Science And Technology Multi-vinylsulfone containing molecule
JP6533932B2 (ja) * 2012-12-28 2019-06-26 アボット カーディオバスキュラー システムズ インコーポレイテッド 抗体を含む治療用組成物
KR101637883B1 (ko) * 2015-09-30 2016-07-21 선바이오(주) 폴리에틸렌글리콜 수화젤 주사제
EP3359200B1 (en) * 2015-10-05 2023-08-02 Board of Regents, The University of Texas System Micro-and nano-device for cartilage injury detection and treatment
AU2016353345B2 (en) 2015-11-12 2021-12-23 University Of Virginia Patent Foundation Compositions and methods for vas-occlusive contraception and reversal thereof
JP7086077B2 (ja) * 2016-08-31 2022-06-17 アンスティトゥート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシャルシュ・メディカル・（インセルム） 局所領域的腫瘍治療後の免疫調節
CN106421925B (zh) * 2016-09-08 2019-01-29 中国医学科学院生物医学工程研究所 基于糖胺聚糖仿生细胞外基质水凝胶作为胰岛培养支架的制备方法
CN106474537A (zh) * 2016-10-18 2017-03-08 南京盛骏医疗科技有限公司 一种制备用于战创伤的液体绷带的方法
CN106769502A (zh) * 2016-12-02 2017-05-31 杭州亚慧生物科技有限公司 一种外科手术封合剂胀破强度检测装置
CN107063873A (zh) * 2016-12-02 2017-08-18 杭州亚慧生物科技有限公司 一种外科手术封合剂恒温胀破强度检测装置
WO2019046834A1 (en) * 2017-09-01 2019-03-07 Pmidg, Llc FUNCTIONALIZED AND RETICULATED POLYMERS
US20200254004A1 (en) * 2017-09-19 2020-08-13 The Hong Kong University Of Science And Technology Biocompatible material and methods for making and using thereof
CN109045354B (zh) * 2018-07-26 2020-12-08 华中科技大学 一种用于骨-软骨综合修复的原位成型可注射水凝胶
CA3117577A1 (en) 2018-11-13 2020-05-22 Contraline, Inc. Systems and methods for delivering biomaterials
CA3133348A1 (en) * 2019-03-15 2020-09-24 Poly-Med, Inc. In situ gel-forming delivery systems, methods and compositions
WO2021231717A1 (en) * 2020-05-14 2021-11-18 Contraline, Inc. Biomaterial compositions and methods of delivery
EP4031113A4 (en) * 2019-09-17 2023-10-11 Topical Sinus Therapeutics, Inc. THERAPEUTIC USES AND METHODS OF ADMINISTRATION OF VISCOUS COMPOSITIONS DURING PRE- AND POST-SURGICAL PERIODS, FOR THE TREATMENT OF SENSITIVE DISEASES OF THE EAR, NOSE AND THROAT
JP2023510380A (ja) * 2020-01-16 2023-03-13 香港科技大学 標的剤の放出制御のための組成物及び方法
CN115364044A (zh) * 2022-06-17 2022-11-22 浙江大学医学院附属第一医院 一种药物组合物及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
WO2005046747A2 (en) 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US20050148512A1 (en) 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
WO2005051452A2 (en) 2003-11-20 2005-06-09 Angiotech International Ag Polymer compositions and methods for their use
JP5198859B2 (ja) 2004-08-02 2013-05-15 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 位相マッピングと、位相基準として用いる基準媒体が関係するｍｒｉ温度測定
PL1817347T3 (pl) 2004-11-24 2017-10-31 Albumedix As Sposób sieciowania kwasu hialuronowego za pomocą diwinylosulfonu
WO2006124021A1 (en) 2005-05-12 2006-11-23 Angiotech International Ag Compositions and methods for treating diverticular disease
EP1978930A2 (en) 2006-01-31 2008-10-15 Angiotech Pharmaceuticals, Inc. Sutures and anti-scarring agents
JP5399716B2 (ja) * 2006-03-02 2014-01-29 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ アリール／アルキルビニルスルホンヒアルロン酸誘導体
EP2117513A2 (en) * 2007-02-05 2009-11-18 Carbylan Biosurgery, Inc. Polymer formulations for delivery of bioactive agents
CN101338036B (zh) * 2007-07-06 2010-11-03 常州百瑞吉生物医药有限公司 生物相容快速凝胶化水凝胶及其喷雾剂的制备方法
AU2010276574B2 (en) * 2009-07-30 2015-08-20 Carbylan Therapeutics, Inc. Modified hyaluronic acid polymer compositions and related methods
US8273725B2 (en) 2009-09-10 2012-09-25 Genzyme Corporation Stable hyaluronan/steroid formulation

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DK2699274T3 (en) 2015-06-15
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US9492383B2 (en) 2016-11-15
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AU2012245517B2 (en) 2015-07-30
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