MX2013009240A - Preparacion farmaceutica de pelicula que contiene sildenafil en su forma de base libre y metodo para producir dicha preparacion. - Google Patents

Preparacion farmaceutica de pelicula que contiene sildenafil en su forma de base libre y metodo para producir dicha preparacion.

Info

Publication number
MX2013009240A
MX2013009240A MX2013009240A MX2013009240A MX2013009240A MX 2013009240 A MX2013009240 A MX 2013009240A MX 2013009240 A MX2013009240 A MX 2013009240A MX 2013009240 A MX2013009240 A MX 2013009240A MX 2013009240 A MX2013009240 A MX 2013009240A
Authority
MX
Mexico
Prior art keywords
sildenafil
free base
containing film
film preparation
producing same
Prior art date
Application number
MX2013009240A
Other languages
English (en)
Other versions
MX349803B (es
Inventor
Hong-Ryeol Jeon
Bong-Sang Lee
Su Jun Park
Bong-Geun Cha
Jun-Ki Kim
Original Assignee
Ctc Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ctc Bio Inc filed Critical Ctc Bio Inc
Publication of MX2013009240A publication Critical patent/MX2013009240A/es
Publication of MX349803B publication Critical patent/MX349803B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Moulding By Coating Moulds (AREA)

Abstract

La presente invención proporciona un método para preparar una película que comprende una cantidad alta de sildenafil en su forma de base libre dispersado de manera uniforme en la misma y que tiene un espesor y tamaño adecuados, así como flexibilidad que proporciona buena estabilidad ante la manipulación y que no es propensa a la rotura. La presente invención también proporciona una película que contiene sildenafil en su forma de base libre preparada a partir del método.
MX2013009240A 2011-02-11 2012-02-13 Preparación farmacéutica de película que contiene sildenafil en su forma de base libre y método para producir dicha preparación. MX349803B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20110012516 2011-02-11
PCT/KR2012/001049 WO2012108738A2 (ko) 2011-02-11 2012-02-13 실데나필 유리염기 함유 필름 제제 및 이의 제조 방법

Publications (2)

Publication Number Publication Date
MX2013009240A true MX2013009240A (es) 2013-08-29
MX349803B MX349803B (es) 2017-08-14

Family

ID=46639094

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013009240A MX349803B (es) 2011-02-11 2012-02-13 Preparación farmacéutica de película que contiene sildenafil en su forma de base libre y método para producir dicha preparación.

Country Status (19)

Country Link
US (1) US9907759B2 (es)
EP (1) EP2674154B1 (es)
JP (1) JP5973467B2 (es)
KR (1) KR102010577B1 (es)
CN (2) CN103402504B (es)
AU (1) AU2012214939B2 (es)
BR (1) BR112013020237A2 (es)
CA (1) CA2827069C (es)
EA (2) EA027720B1 (es)
ES (1) ES2691629T3 (es)
IL (1) IL227931A (es)
MA (1) MA34960B1 (es)
MX (1) MX349803B (es)
MY (1) MY163288A (es)
SG (1) SG192284A1 (es)
TN (1) TN2013000342A1 (es)
UA (1) UA112540C2 (es)
WO (1) WO2012108738A2 (es)
ZA (1) ZA201306650B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104168895B (zh) 2012-02-28 2020-02-21 首尔制药株式会社 包含西地那非作为活性成分的掩蔽苦味的高含量快速溶解膜
WO2014137189A1 (ko) * 2013-03-07 2014-09-12 에스케이케미칼주식회사 고함량의 약물을 함유하는 구강 붕해 필름 및 이의 제조방법
US11116769B2 (en) 2013-04-11 2021-09-14 Ctc Bio, Inc. Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer
KR102223105B1 (ko) * 2013-04-11 2021-03-04 주식회사 씨티씨바이오 분산안정화제로 폴리에틸렌글리콜계 고분자 및/또는 비닐피롤리돈계 고분자를 포함하는 타다라필 유리염기 함유 필름 제형
MX370064B (es) * 2013-05-10 2019-11-29 Ctc Bio Inc Preparación de película que contiene donepezilo en su forma de base libre y método para producirla.
CN104352462A (zh) * 2014-10-22 2015-02-18 张艳芬 一种提高昔多芬药物功效的方法
ES2584248B1 (es) * 2015-03-24 2017-04-19 Farmalider, S.A. Composición farmacéutica de citrato de sildenafilo en forma de suspensión para uso oral
CN110678555B (zh) 2017-04-14 2023-10-13 比利时胶囊公司 制作普鲁兰的方法
US11576870B2 (en) 2017-04-14 2023-02-14 Capsugel Belgium Nv Pullulan capsules
CN109010324B (zh) * 2018-08-30 2021-07-02 南京康川济医药科技有限公司 一种西地那非口溶膜剂及其制备方法
US11179331B1 (en) 2020-04-21 2021-11-23 Cure Pharmaceutcai Holding Corp Oral soluble film containing sildenafil citrate

Family Cites Families (15)

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CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
GT199900061A (es) * 1998-05-15 2000-10-14 Pfizer Formulaciones farmaceuticas.
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
JP4173670B2 (ja) * 2002-03-08 2008-10-29 旭化成ファーマ株式会社 口腔内崩壊製剤
JP5148801B2 (ja) * 2002-09-09 2013-02-20 エスエス製薬株式会社 催眠用固形製剤
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20050042177A1 (en) 2003-07-23 2005-02-24 Elan Pharma International Ltd. Novel compositions of sildenafil free base
JP4547994B2 (ja) 2004-06-02 2010-09-22 救急薬品工業株式会社 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤
MX2007009635A (es) 2005-02-10 2007-09-25 Orexo Ab Nuevas composiciones farmaceuticas utiles en la administracion transmucosa de farmacos.
KR20090034882A (ko) * 2006-06-16 2009-04-08 테이트 앤 라일 인그리디언츠 아메리카스, 인코포레이티드 풀룰란 필름 및 식용 포장에서의 이들의 용도
HUE038022T4 (hu) * 2006-10-02 2023-02-28 Spepharm Ag Nem mukoadhezív filmdózisformák
US20090047330A1 (en) * 2007-08-17 2009-02-19 Ramesh Bangalore Oral fast dissolving films for erectile dysfunction bioactive agents
KR100920106B1 (ko) 2007-11-14 2009-10-01 경북대학교 산학협력단 구연산 실데나필을 경피적으로 전달하기 위한 조절 약물전달체 및 이를 포함하는 경피 패치
KR101074271B1 (ko) * 2009-06-25 2011-10-17 (주)차바이오앤디오스텍 불쾌한 맛을 효과적으로 은폐한 경구용 속용 필름
KR20110041412A (ko) 2009-10-15 2011-04-21 (주)씨엘팜 Ｐｄｅ5 억제제를 함유하는 구강 용해성 필름

Also Published As

Publication number Publication date
EA201500604A1 (ru) 2015-09-30
ZA201306650B (en) 2015-06-24
MX349803B (es) 2017-08-14
MA34960B1 (fr) 2014-03-01
UA112540C2 (uk) 2016-09-26
AU2012214939B2 (en) 2016-11-17
EA201391156A1 (ru) 2014-02-28
WO2012108738A3 (ko) 2012-10-26
KR102010577B1 (ko) 2019-08-13
JP2014505098A (ja) 2014-02-27
WO2012108738A2 (ko) 2012-08-16
IL227931A (en) 2017-03-30
MY163288A (en) 2017-08-30
EP2674154A2 (en) 2013-12-18
TN2013000342A1 (en) 2015-01-20
CA2827069A1 (en) 2012-08-16
EP2674154B1 (en) 2018-08-01
CA2827069C (en) 2021-02-16
JP5973467B2 (ja) 2016-08-23
CN105250242B (zh) 2018-09-21
CN105250242A (zh) 2016-01-20
US20130323307A1 (en) 2013-12-05
CN103402504A (zh) 2013-11-20
EA027720B1 (ru) 2017-08-31
CN103402504B (zh) 2015-10-14
ES2691629T3 (es) 2018-11-28
IL227931A0 (en) 2013-09-30
KR20120101301A (ko) 2012-09-13
AU2012214939A1 (en) 2013-09-19
US9907759B2 (en) 2018-03-06
SG192284A1 (en) 2013-09-30
EP2674154A4 (en) 2015-04-01
BR112013020237A2 (pt) 2021-03-16

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