MX2013008189A - Composiciones de alta penetracion y metodos para tratar lesiones en los tejidos inducidas por agentes patogenos. - Google Patents
Composiciones de alta penetracion y metodos para tratar lesiones en los tejidos inducidas por agentes patogenos.Info
- Publication number
- MX2013008189A MX2013008189A MX2013008189A MX2013008189A MX2013008189A MX 2013008189 A MX2013008189 A MX 2013008189A MX 2013008189 A MX2013008189 A MX 2013008189A MX 2013008189 A MX2013008189 A MX 2013008189A MX 2013008189 A MX2013008189 A MX 2013008189A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- treatment
- benzocaine
- compositions
- treatment composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Materials For Medical Uses (AREA)
Abstract
Composiciones y métodos para tratar trastornos en tejidos, tales como los ocasionados por agentes patógenos y/o toxinas. Las composiciones de tratamiento incluyen un agente antiinfeccioso activo, un portador líquido y benzocaína en cantidad suficiente para que la composición de tratamiento penetre más rápidamente en el tejido con trastorno en comparación con la misma composición de tratamiento en ausencia de la benzocaína. Además, la benzocaína puede aumentar el tiempo de contacto del agente antiinfeccioso activo en el área de tratamiento. El agente antiinfeccioso activo preferido puede ser un organohaluro, tal como un compuesto haluro de amonio cuaternario, un ejemplo del cual es el cloruro de benzalconio. Las composiciones y los métodos de tratamiento pueden utilizar un aplicador adaptado para su uso en la promoción de la penetración de la composición de tratamiento y/o la agitación del tejido con trastorno para incrementar aún más la penetración.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/012,719 US8846725B2 (en) | 2011-01-24 | 2011-01-24 | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
PCT/US2012/021877 WO2012102936A1 (en) | 2011-01-24 | 2012-01-19 | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013008189A true MX2013008189A (es) | 2013-08-21 |
MX336765B MX336765B (es) | 2016-01-29 |
Family
ID=45563563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013008189A MX336765B (es) | 2011-01-24 | 2012-01-19 | Composiciones de alta penetracion y metodos para tratar lesiones en los tejidos inducidas por agentes patogenos. |
Country Status (12)
Country | Link |
---|---|
US (4) | US8846725B2 (es) |
EP (1) | EP2667865A1 (es) |
JP (1) | JP6039584B2 (es) |
KR (2) | KR20140005996A (es) |
AU (1) | AU2012209412B2 (es) |
BR (1) | BR112013018901A2 (es) |
CA (1) | CA2824766A1 (es) |
IL (1) | IL227566A0 (es) |
MX (1) | MX336765B (es) |
RU (1) | RU2586969C2 (es) |
TW (1) | TWI503133B (es) |
WO (1) | WO2012102936A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8846725B2 (en) * | 2011-01-24 | 2014-09-30 | Quadex Pharmaceuticals, Llc | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
US9463180B2 (en) | 2013-03-14 | 2016-10-11 | Quadex Pharmaceuticals, Llc | Treatment of molluscum contagiosum |
US9125911B2 (en) * | 2013-03-14 | 2015-09-08 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered tissues |
US9549930B2 (en) | 2013-03-14 | 2017-01-24 | Quadex Pharmaceuticals, Llc | Combined systemic and topical treatment of disordered and/or prodromal stage tissue |
US11759418B1 (en) * | 2016-07-15 | 2023-09-19 | Chrism Products, Inc. | Composition for treating wounds, dermatitis, inflammation, and irritation |
AU2018225661A1 (en) * | 2017-02-22 | 2019-09-19 | Dermal Biomics, Inc. | Nonwoven wipes, cleaning compositions, and associated packaging |
MX2020008850A (es) | 2018-02-23 | 2021-03-09 | The Administrators Of The Tulane Educational Fund | Composicion farmaceutica para infecciones virales. |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1519693A (en) | 1924-03-05 | 1924-12-16 | Fred R Moore | Rotary medicine applicator |
US3832460A (en) | 1971-03-19 | 1974-08-27 | C Kosti | Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue |
US4199574A (en) | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
GB1574302A (en) | 1977-06-27 | 1980-09-03 | Scherico Ltd | Stable sprayable anesthetic solution |
US4176197A (en) | 1978-02-03 | 1979-11-27 | Dominion Pharmacal, Inc. | Method for treating acne vulgaris |
US4390539A (en) | 1979-04-13 | 1983-06-28 | George F. And Irene Sherrill 1978 Trust No. 1 | Method for the treatment of viral skin diseases |
US4262007A (en) | 1979-04-13 | 1981-04-14 | George F. Sherrill | Method for the treatment of viral skin diseases |
EP0053754B1 (de) | 1980-12-06 | 1986-04-23 | Reichert, Dietrich, Dr. med. | Mittel zur Bekämpfung des Schnarchens und Verfahren zu dessen Anwendung |
ZA853488B (en) * | 1984-05-10 | 1986-12-30 | American Home Prod | Transdermal dosage form |
JPS6176401A (ja) | 1984-09-19 | 1986-04-18 | Takeda Chem Ind Ltd | 殺菌消毒剤および殺菌消毒法 |
EP0175338A3 (en) | 1984-09-19 | 1988-06-01 | Takeda Chemical Industries, Ltd. | Disinfectants and antiseptics |
EP0190797A3 (en) | 1985-02-08 | 1987-05-20 | John Kenneth Voit | Method for killing viruses and composition therefor |
US4895727A (en) | 1985-05-03 | 1990-01-23 | Chemex Pharmaceuticals, Inc. | Pharmaceutical vehicles for exhancing penetration and retention in the skin |
CA1273576A (en) | 1987-09-16 | 1990-09-04 | Patrick A. Beauchamp | Topical treatment for diseased skin disorders |
US4952204A (en) | 1988-08-10 | 1990-08-28 | Gam-Med Packaging Corporation | Dry handle swab assembly and unit |
US4874794A (en) | 1989-04-28 | 1989-10-17 | Lidak Biopharmaceuticals | Inflammatory disease treatment |
US4979420A (en) | 1990-01-22 | 1990-12-25 | Cusack John F | Stainless steel reed |
US6355684B1 (en) | 1990-10-11 | 2002-03-12 | Meryl J. Squires | Antimicrobial treatment for herpes simplex virus and other infectious diseases |
JP3055796B2 (ja) | 1990-11-19 | 2000-06-26 | 善蔵 田村 | 殺菌消毒剤組成物 |
US5403864A (en) | 1993-04-01 | 1995-04-04 | John A. Manfuso, Jr. | Rapidly-acting topical antimicrobial composition |
US5445462A (en) | 1993-08-03 | 1995-08-29 | Medi-Flex Hospital Products, Inc. | Liquid applicator |
DE4328828A1 (de) | 1993-08-27 | 1995-03-02 | Bode Chemie Gmbh & Co | Alkoholisches Händedesinfektionsmittel mit Hautpflegekomponente |
US5492932A (en) | 1994-02-22 | 1996-02-20 | Kundsin Leduc Lenmark, Inc. | Lubrication germicidal composition |
US5767163A (en) | 1994-02-22 | 1998-06-16 | Kundsin Leduc Lenmark Inc. | Lubricating and/or germicidal composition |
US5540934A (en) | 1994-06-22 | 1996-07-30 | Touitou; Elka | Compositions for applying active substances to or through the skin |
JPH08164191A (ja) | 1994-12-13 | 1996-06-25 | Kankyo Planning:Kk | 消毒・除菌用ウエットティッシュ |
NL9500216A (nl) | 1995-02-06 | 1996-09-02 | Bio Pharma Sciences Bv | Farmaceutische samenstelling voor de behandeling van herpes. |
JPH08217694A (ja) | 1995-02-09 | 1996-08-27 | Pola Chem Ind Inc | 抗掻痒皮膚外用剤 |
US5631245A (en) | 1995-06-06 | 1997-05-20 | Biodynamics Pharmaceuticals, Inc. | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions |
US5704906A (en) | 1996-02-26 | 1998-01-06 | Fox; Richard L. | Method of using a topical anesthetic-cleaning solution and applicator |
JPH10324624A (ja) | 1997-05-23 | 1998-12-08 | Kao Corp | 殺菌消毒剤組成物 |
GB9718791D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Medicaments |
SE9703458D0 (sv) * | 1997-09-25 | 1997-09-25 | Pharmacia & Upjohn Ab | Nicotine compositions and methods of formulation thereof |
AU9186398A (en) | 1997-09-26 | 1999-04-23 | Wakamoto Pharmaceutical Co., Ltd. | Aqueous preparation containing antiviral agent having purine or pyrimidine skeleton |
US6022551A (en) | 1998-01-20 | 2000-02-08 | Ethicon, Inc. | Antimicrobial composition |
US6759434B2 (en) | 1999-09-22 | 2004-07-06 | B. Ron Johnson | Anti-infective compositions, methods and systems for treating disordered tissue |
US8173709B2 (en) | 1999-09-22 | 2012-05-08 | Quadex Pharmaceuticals, Llc | Anti-infective methods for treating pathogen-induced disordered tissues |
US6211243B1 (en) | 1999-09-22 | 2001-04-03 | B. Ron Johnson | Methods for treating cold sores with anti-infective compositions |
US6379702B1 (en) * | 2000-07-05 | 2002-04-30 | Hydromer, Inc. | Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives |
US6830758B2 (en) * | 2001-04-02 | 2004-12-14 | Lectec Corporation | Psoriasis patch |
US20050014823A1 (en) * | 2003-07-17 | 2005-01-20 | Soderlund Patrick L. | Topical anesthetic composition and method of administration |
US20060229364A1 (en) * | 2005-03-10 | 2006-10-12 | 3M Innovative Properties Company | Antiviral compositions and methods of use |
US20110288123A1 (en) * | 2008-11-06 | 2011-11-24 | Nuvo Research Inc. | Formulations for the treatment of acute herpes zoster pain |
US8846725B2 (en) * | 2011-01-24 | 2014-09-30 | Quadex Pharmaceuticals, Llc | Highly penetrating compositions and methods for treating pathogen-induced disordered tissues |
-
2011
- 2011-01-24 US US13/012,719 patent/US8846725B2/en not_active Expired - Fee Related
-
2012
- 2012-01-19 MX MX2013008189A patent/MX336765B/es unknown
- 2012-01-19 CA CA2824766A patent/CA2824766A1/en not_active Abandoned
- 2012-01-19 JP JP2013552020A patent/JP6039584B2/ja not_active Expired - Fee Related
- 2012-01-19 WO PCT/US2012/021877 patent/WO2012102936A1/en active Application Filing
- 2012-01-19 KR KR1020137022305A patent/KR20140005996A/ko active Application Filing
- 2012-01-19 BR BR112013018901A patent/BR112013018901A2/pt not_active Application Discontinuation
- 2012-01-19 AU AU2012209412A patent/AU2012209412B2/en not_active Ceased
- 2012-01-19 EP EP12702683.9A patent/EP2667865A1/en not_active Withdrawn
- 2012-01-19 KR KR1020187018264A patent/KR20180077306A/ko not_active Application Discontinuation
- 2012-01-19 RU RU2013139163/14A patent/RU2586969C2/ru not_active IP Right Cessation
- 2012-01-30 TW TW101102949A patent/TWI503133B/zh not_active IP Right Cessation
-
2013
- 2013-07-21 IL IL227566A patent/IL227566A0/en active IP Right Grant
-
2014
- 2014-08-22 US US14/466,625 patent/US9314526B2/en active Active
- 2014-08-22 US US14/466,637 patent/US20140364496A1/en not_active Abandoned
-
2017
- 2017-06-21 US US15/629,317 patent/US20180028666A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NZ613262A (en) | 2015-10-30 |
JP6039584B2 (ja) | 2016-12-07 |
US9314526B2 (en) | 2016-04-19 |
US20140364496A1 (en) | 2014-12-11 |
BR112013018901A2 (pt) | 2017-03-28 |
IL227566A0 (en) | 2013-09-30 |
AU2012209412B2 (en) | 2016-09-15 |
JP2014503603A (ja) | 2014-02-13 |
WO2012102936A1 (en) | 2012-08-02 |
US20140364495A1 (en) | 2014-12-11 |
TW201309342A (zh) | 2013-03-01 |
TWI503133B (zh) | 2015-10-11 |
RU2013139163A (ru) | 2015-03-10 |
CA2824766A1 (en) | 2012-08-02 |
RU2586969C2 (ru) | 2016-06-10 |
MX336765B (es) | 2016-01-29 |
EP2667865A1 (en) | 2013-12-04 |
KR20180077306A (ko) | 2018-07-06 |
KR20140005996A (ko) | 2014-01-15 |
US8846725B2 (en) | 2014-09-30 |
US20120190715A1 (en) | 2012-07-26 |
US20180028666A1 (en) | 2018-02-01 |
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