SG10201810404XA - Combination comprising a glucocorticoid and edo-s101 - Google Patents

Combination comprising a glucocorticoid and edo-s101

Info

Publication number
SG10201810404XA
SG10201810404XA SG10201810404XA SG10201810404XA SG10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA SG 10201810404X A SG10201810404X A SG 10201810404XA
Authority
SG
Singapore
Prior art keywords
combination
glucocorticoid
edo
kit
composition
Prior art date
Application number
SG10201810404XA
Inventor
Thomas Jorg Mehrling
Enrique Maria Ocio
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of SG10201810404XA publication Critical patent/SG10201810404XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

COMBINATION COMPRISING A GLUCOCORTICOID AND EDO-S101 The present invention is directed to a combination comprising a glucocorticoid and a compound of formula I or a pharmaceutically acceptable salt thereof: ( I ) to a pharmaceutical composition and to a kit both comprising said combination, to the combination, composition or kit for use in the treatment of cancer, and to a method of treatment of cancer in a patient in need thereof comprising administering to said patient an effective amount of said combination, composition or kit. Figure 2 N N N Cl Cl HN OH O
SG10201810404XA 2014-05-28 2015-05-26 Combination comprising a glucocorticoid and edo-s101 SG10201810404XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1409485.8A GB201409485D0 (en) 2014-05-28 2014-05-28 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
SG10201810404XA true SG10201810404XA (en) 2018-12-28

Family

ID=51177587

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201810404XA SG10201810404XA (en) 2014-05-28 2015-05-26 Combination comprising a glucocorticoid and edo-s101
SG11201609362YA SG11201609362YA (en) 2014-05-28 2015-05-26 Combination comprising a glucocorticoid and edo-s101

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201609362YA SG11201609362YA (en) 2014-05-28 2015-05-26 Combination comprising a glucocorticoid and edo-s101

Country Status (19)

Country Link
US (3) US10744120B2 (en)
EP (1) EP3148584B1 (en)
JP (2) JP2017518292A (en)
KR (1) KR20170008846A (en)
CN (1) CN106488776B (en)
AU (1) AU2015266053B2 (en)
BR (1) BR112016027043B1 (en)
CA (1) CA2950340C (en)
DK (1) DK3148584T3 (en)
EA (1) EA038323B1 (en)
ES (1) ES2885429T3 (en)
GB (1) GB201409485D0 (en)
IL (1) IL249230A0 (en)
MX (1) MX2016015437A (en)
PH (1) PH12016502352A1 (en)
SG (2) SG10201810404XA (en)
TW (1) TWI731837B (en)
UA (1) UA121392C2 (en)
WO (1) WO2015181157A1 (en)

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GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
AU2019402158A1 (en) * 2018-12-18 2021-06-10 Mundipharma International Corporation Limited Compounds for treating lymphoma or a T-cell malignant disease

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Also Published As

Publication number Publication date
BR112016027043A2 (en) 2017-08-15
UA121392C2 (en) 2020-05-25
CA2950340A1 (en) 2015-12-03
IL249230A0 (en) 2017-02-28
US11541038B2 (en) 2023-01-03
TW201613577A (en) 2016-04-16
GB201409485D0 (en) 2014-07-09
AU2015266053B2 (en) 2020-07-02
ES2885429T3 (en) 2021-12-13
US20230285363A1 (en) 2023-09-14
AU2015266053A1 (en) 2016-11-17
TWI731837B (en) 2021-07-01
JP2021046446A (en) 2021-03-25
EA038323B1 (en) 2021-08-10
DK3148584T3 (en) 2021-08-30
CN106488776B (en) 2021-01-22
PH12016502352A1 (en) 2017-02-13
CA2950340C (en) 2023-10-17
EA201692481A1 (en) 2017-04-28
US20170296513A1 (en) 2017-10-19
CN106488776A (en) 2017-03-08
EP3148584A1 (en) 2017-04-05
JP2017518292A (en) 2017-07-06
US20210059989A1 (en) 2021-03-04
SG11201609362YA (en) 2016-12-29
BR112016027043A8 (en) 2021-07-20
MX2016015437A (en) 2017-06-23
BR112016027043B1 (en) 2023-01-31
KR20170008846A (en) 2017-01-24
EP3148584B1 (en) 2021-05-26
WO2015181157A1 (en) 2015-12-03
US10744120B2 (en) 2020-08-18

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