MX2013007371A - Peptidos de enlace her2 radiomarcados. - Google Patents
Peptidos de enlace her2 radiomarcados.Info
- Publication number
- MX2013007371A MX2013007371A MX2013007371A MX2013007371A MX2013007371A MX 2013007371 A MX2013007371 A MX 2013007371A MX 2013007371 A MX2013007371 A MX 2013007371A MX 2013007371 A MX2013007371 A MX 2013007371A MX 2013007371 A MX2013007371 A MX 2013007371A
- Authority
- MX
- Mexico
- Prior art keywords
- radiolabled
- binding peptides
- her2 binding
- her2
- isolated polypeptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
Abstract
Se describen agentes formadores de imagen que comprenden un polipéptido aislado conjugado con un radionúclido y un quelatador; en donde el polipéptido aislado se une específicamente a HER2, o variante del mismo; y métodos para preparar y utilizar estos agentes formadores de imagen.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/975,425 US20120165650A1 (en) | 2010-12-22 | 2010-12-22 | Her2 binders |
US201161438297P | 2011-02-01 | 2011-02-01 | |
US201161510520P | 2011-07-22 | 2011-07-22 | |
US201161541287P | 2011-09-30 | 2011-09-30 | |
PCT/US2011/065777 WO2012096760A1 (en) | 2010-12-22 | 2011-12-19 | Radiolabled her2 binding peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2013007371A true MX2013007371A (es) | 2014-05-27 |
Family
ID=45444771
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013007365A MX2013007365A (es) | 2010-12-22 | 2011-12-19 | Péptidos de enlace her2 etiquetados con fluoruro de aluminio- [18] combinados mediante nota. |
MX2013007371A MX2013007371A (es) | 2010-12-22 | 2011-12-19 | Peptidos de enlace her2 radiomarcados. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013007365A MX2013007365A (es) | 2010-12-22 | 2011-12-19 | Péptidos de enlace her2 etiquetados con fluoruro de aluminio- [18] combinados mediante nota. |
Country Status (13)
Country | Link |
---|---|
EP (4) | EP3936155A1 (es) |
JP (2) | JP2014503546A (es) |
KR (5) | KR102498607B1 (es) |
CN (1) | CN103533963B (es) |
AU (2) | AU2011354599B2 (es) |
BR (2) | BR112013015786A2 (es) |
CA (3) | CA2822815A1 (es) |
IL (1) | IL227003A (es) |
MX (2) | MX2013007365A (es) |
NZ (2) | NZ612161A (es) |
RU (2) | RU2592685C2 (es) |
SG (2) | SG191292A1 (es) |
WO (2) | WO2012096760A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120165650A1 (en) | 2010-12-22 | 2012-06-28 | General Electric Company | Her2 binders |
KR102498607B1 (ko) * | 2010-12-22 | 2023-02-13 | 제너럴 일렉트릭 캄파니 | 방사성표지 her2 결합 펩티드 |
WO2014076179A1 (en) * | 2012-11-14 | 2014-05-22 | Affibody Ab | New polypeptide |
CA2895284A1 (en) * | 2013-02-07 | 2014-08-14 | Immunomedics, Inc. | Pro-drug form (p2pdox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer |
CN103948947A (zh) * | 2013-05-08 | 2014-07-30 | 南京市第一医院 | 以cd13为分子靶点、ngr为配体的放射性核素分子探针及其标记技术和应用 |
EP3014277A4 (en) * | 2013-06-27 | 2017-04-19 | GE Healthcare Limited | Use of her2 binders |
CN103833829A (zh) * | 2014-01-07 | 2014-06-04 | 江苏省原子医学研究所 | 一种放射性18F标记的靶向肿瘤血管Anxa1显像药物18F-AL-NOTA-IF7及其制备方法 |
CN103951754B (zh) * | 2014-03-26 | 2016-08-24 | 中国药科大学 | 一种靶向治疗和检测双功能的抗肿瘤双特异性小型化抗体 |
EP3015462A1 (en) * | 2014-10-29 | 2016-05-04 | OctreoPharm Schiences GmbH | Enantiopure chelating agents for chelator coupled pharmaceuticals, corresponding preparation method thereof and chelator coupled pharmaceuticals |
CA2982269C (en) * | 2015-05-26 | 2023-12-05 | The Regents Of The University Of California | Heteroaromatic silicon-fluoride-acceptors useful for 18f labeling of molecules and biomolecules, and methods of preparing same |
EP3426296A4 (en) * | 2016-03-10 | 2019-11-20 | Becton, Dickinson and Company | METHOD OF EVALUATING A CELLULAR SAMPLE FOR HER-2 / NEU EXPRESSION AND COMPOSITIONS FOR IMPLEMENTING THEREOF |
FR3054445B1 (fr) * | 2016-07-26 | 2019-07-05 | Laboratoires Cyclopharma | Synthese d'une composition d'agent radioactif |
US10695450B2 (en) | 2016-07-26 | 2020-06-30 | Laboratoires Cyclopharma | Synthesis of a radioactive agent composition |
GB2581619A (en) | 2017-09-15 | 2020-08-26 | Univ California | Inhibition of aminoacylase 3 (AA3) in the treatment of cancer |
CN110251695B (zh) * | 2019-07-10 | 2021-12-21 | 莎穆(上海)生物科技有限公司 | 一种靶向her2的放射性配合物及其制备方法和应用 |
US20230040008A1 (en) | 2019-12-18 | 2023-02-09 | Bracco Imaging S.P.A. | Anti-her2 polypeptides derivatives as new diagnostic molecular probes |
AU2020403911A1 (en) | 2019-12-18 | 2022-06-30 | Bracco Imaging Spa | Anti-HER2 polypeptides derivatives as new diagnostic molecular probes |
KR102502287B1 (ko) | 2020-04-17 | 2023-02-22 | 앱클론(주) | 항-her2 어피바디 및 이를 스위치 분자로 이용하는 스위처블 키메라 항원 수용체 |
EP4142806A1 (en) * | 2020-04-30 | 2023-03-08 | Hober Biotech AB | Visualization of her2 expression in human patients |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY133346A (en) * | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
US7563433B2 (en) * | 2007-01-11 | 2009-07-21 | Immunomedics, Inc. | Methods and compositions for F-18 labeling of proteins, peptides and other molecules |
US7993626B2 (en) * | 2007-01-11 | 2011-08-09 | Immunomedics, Inc. | Methods and compositions for F-18 labeling of proteins, peptides and other molecules |
US7772188B2 (en) * | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
GB0305704D0 (en) | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
JP4871126B2 (ja) * | 2003-07-04 | 2012-02-08 | アフィボディ・アーベー | Her2に対する結合親和性を有するポリペプチド |
GB0428012D0 (en) | 2004-12-22 | 2005-01-26 | Hammersmith Imanet Ltd | Radiolabelling methods |
WO2008049866A1 (en) * | 2006-10-27 | 2008-05-02 | Affibody Ab | New chelating compound |
WO2008118601A2 (en) * | 2007-02-27 | 2008-10-02 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Radiolabeled affibody molecules |
US8124725B2 (en) * | 2007-12-19 | 2012-02-28 | General Electric Company | PDGF-Rβ binders |
EP2072525A1 (en) * | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
KR102498607B1 (ko) * | 2010-12-22 | 2023-02-13 | 제너럴 일렉트릭 캄파니 | 방사성표지 her2 결합 펩티드 |
RU2013128360A (ru) * | 2010-12-22 | 2015-01-27 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Her2-связывающие белки, меченые 18f-содержащим кремнийорганическим соединением |
-
2011
- 2011-12-19 KR KR1020217014930A patent/KR102498607B1/ko active IP Right Grant
- 2011-12-19 NZ NZ612161A patent/NZ612161A/en unknown
- 2011-12-19 KR KR1020137019116A patent/KR20140045312A/ko active Search and Examination
- 2011-12-19 WO PCT/US2011/065777 patent/WO2012096760A1/en active Application Filing
- 2011-12-19 RU RU2013128358/10A patent/RU2592685C2/ru active
- 2011-12-19 NZ NZ612312A patent/NZ612312A/en not_active IP Right Cessation
- 2011-12-19 CA CA2822815A patent/CA2822815A1/en not_active Abandoned
- 2011-12-19 EP EP21190695.3A patent/EP3936155A1/en active Pending
- 2011-12-19 EP EP21190694.6A patent/EP3957332A1/en active Pending
- 2011-12-19 SG SG2013048061A patent/SG191292A1/en unknown
- 2011-12-19 BR BR112013015786-0A patent/BR112013015786A2/pt not_active IP Right Cessation
- 2011-12-19 KR KR1020237004408A patent/KR20230034403A/ko not_active Application Discontinuation
- 2011-12-19 RU RU2013128361/10A patent/RU2013128361A/ru not_active Application Discontinuation
- 2011-12-19 JP JP2013546277A patent/JP2014503546A/ja active Pending
- 2011-12-19 WO PCT/US2011/065794 patent/WO2012087908A1/en active Application Filing
- 2011-12-19 KR KR1020187010276A patent/KR20180042442A/ko active Application Filing
- 2011-12-19 AU AU2011354599A patent/AU2011354599B2/en active Active
- 2011-12-19 EP EP11804897.4A patent/EP2654804A1/en not_active Withdrawn
- 2011-12-19 EP EP11804895.8A patent/EP2654803B1/en active Active
- 2011-12-19 MX MX2013007365A patent/MX2013007365A/es not_active Application Discontinuation
- 2011-12-19 CA CA3159948A patent/CA3159948A1/en active Pending
- 2011-12-19 KR KR1020137019088A patent/KR20130132935A/ko not_active Application Discontinuation
- 2011-12-19 CA CA2822693A patent/CA2822693C/en active Active
- 2011-12-19 AU AU2011349482A patent/AU2011349482A1/en not_active Abandoned
- 2011-12-19 CN CN201180068114.4A patent/CN103533963B/zh not_active Expired - Fee Related
- 2011-12-19 JP JP2013546278A patent/JP2014507400A/ja active Pending
- 2011-12-19 MX MX2013007371A patent/MX2013007371A/es unknown
- 2011-12-19 BR BR112013015796A patent/BR112013015796A2/pt not_active IP Right Cessation
- 2011-12-19 SG SG2013047725A patent/SG191270A1/en unknown
-
2013
- 2013-06-17 IL IL227003A patent/IL227003A/en active IP Right Grant
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