MX2013005392A - Compuestos de hidroxiamida pirimidina como inhibidores de la proteina deacetilasa y metodo de uso de estos. - Google Patents

Compuestos de hidroxiamida pirimidina como inhibidores de la proteina deacetilasa y metodo de uso de estos.

Info

Publication number
MX2013005392A
MX2013005392A MX2013005392A MX2013005392A MX2013005392A MX 2013005392 A MX2013005392 A MX 2013005392A MX 2013005392 A MX2013005392 A MX 2013005392A MX 2013005392 A MX2013005392 A MX 2013005392A MX 2013005392 A MX2013005392 A MX 2013005392A
Authority
MX
Mexico
Prior art keywords
methods
amide compounds
hydroxy amide
deacetylase inhibitors
protein deacetylase
Prior art date
Application number
MX2013005392A
Other languages
English (en)
Spanish (es)
Inventor
John H Van Duzer
Ralph Mazitschek
Yanbing Ding
Nan Yu
Yun Cao
Yong Liu
Original Assignee
Acetylon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46047943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013005392(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acetylon Pharmaceuticals Inc filed Critical Acetylon Pharmaceuticals Inc
Publication of MX2013005392A publication Critical patent/MX2013005392A/es

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    • C—CHEMISTRY; METALLURGY
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
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  • Hospice & Palliative Care (AREA)
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MX2013005392A 2010-11-16 2011-11-15 Compuestos de hidroxiamida pirimidina como inhibidores de la proteina deacetilasa y metodo de uso de estos. MX2013005392A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41415810P 2010-11-16 2010-11-16
US201161503286P 2011-06-30 2011-06-30
PCT/US2011/060791 WO2012068109A2 (en) 2010-11-16 2011-11-15 Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2013005392A true MX2013005392A (es) 2013-07-29

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MX2013005392A MX2013005392A (es) 2010-11-16 2011-11-15 Compuestos de hidroxiamida pirimidina como inhibidores de la proteina deacetilasa y metodo de uso de estos.

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US (3) US8614223B2 (cg-RX-API-DMAC7.html)
EP (2) EP2640709B1 (cg-RX-API-DMAC7.html)
JP (2) JP6041808B2 (cg-RX-API-DMAC7.html)
KR (1) KR20130115300A (cg-RX-API-DMAC7.html)
CN (2) CN107011270A (cg-RX-API-DMAC7.html)
AU (2) AU2011329028B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013011868A2 (cg-RX-API-DMAC7.html)
CA (1) CA2818125A1 (cg-RX-API-DMAC7.html)
CL (1) CL2013001381A1 (cg-RX-API-DMAC7.html)
EA (2) EA025345B1 (cg-RX-API-DMAC7.html)
ES (1) ES2568260T3 (cg-RX-API-DMAC7.html)
IL (2) IL226326A0 (cg-RX-API-DMAC7.html)
MX (1) MX2013005392A (cg-RX-API-DMAC7.html)
NZ (2) NZ710405A (cg-RX-API-DMAC7.html)
PH (2) PH12013500964A1 (cg-RX-API-DMAC7.html)
PL (1) PL2640709T3 (cg-RX-API-DMAC7.html)
PT (1) PT2640709T (cg-RX-API-DMAC7.html)
SG (2) SG190211A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012068109A2 (cg-RX-API-DMAC7.html)

Families Citing this family (55)

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Publication number Priority date Publication date Assignee Title
PL2526093T3 (pl) 2010-01-22 2017-02-28 Acetylon Pharmaceuticals, Inc. Odwrócone związki amidowe jako inhibitory deacetylazy białkowej oraz sposoby ich stosowania
WO2012068109A2 (en) 2010-11-16 2012-05-24 Acetylon Pharmaceuticals Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
CA2868302A1 (en) 2012-03-23 2013-09-26 Dennis M. Brown Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo
EP2839037B1 (en) 2012-04-19 2018-12-26 Acetylon Pharmaceuticals, Inc. Biomarkers to identify patients that will respond to treatment and treating such patients
HK1213471A1 (zh) * 2012-10-12 2016-07-08 The Trustees Of The University Of Pennsylvania 作為蛋白脫乙酰基酶抑制劑的嘧啶羥基酰胺化合物及其使用方法
US9145412B2 (en) 2012-11-02 2015-09-29 Acetylon Pharmaceuticals, Inc. Selective HDAC1 and HDAC2 inhibitors
WO2014159218A1 (en) 2013-03-14 2014-10-02 Chdi Foundation, Inc. Histone deacetylase inhibitors and compositions
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