MX2013004832A - Compuestos y composiciones para el tratamiento del cancer. - Google Patents
Compuestos y composiciones para el tratamiento del cancer.Info
- Publication number
- MX2013004832A MX2013004832A MX2013004832A MX2013004832A MX2013004832A MX 2013004832 A MX2013004832 A MX 2013004832A MX 2013004832 A MX2013004832 A MX 2013004832A MX 2013004832 A MX2013004832 A MX 2013004832A MX 2013004832 A MX2013004832 A MX 2013004832A
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- compounds
- cancer
- treatment
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/32—Phenylacetic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/48—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/18—Saturated compounds containing keto groups
- C07C62/20—Saturated compounds containing keto groups with a saturated six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/04—Monocyclic monocarboxylic acids
- C07C63/06—Benzoic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/04—Monocyclic monocarboxylic acids
- C07C63/06—Benzoic acid
- C07C63/08—Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Nuevos usos para compuestos de carboxilato de fenilcetona y compuestos aromáticos sustituidos de Fórmula I, Fórmula I.1, Fórmula I.2, Fórmula lA, Fórmula IB, Fórmula IC y Fórmula II y sus sales farmacéuticamente aceptables para el tratamiento del cáncer. Se describe el uso de una combinación de dos de estos compuestos y el uso de la combinación de uno de estos compuestos con un agente anticanceroso, tal como decarbazina, doxorrubicina, daunorrubicina, ciclofosfamida, busulfex, busulfán, vinblastina, vincristina, bleomicina, etopósido, topotecán, irinotecán, taxotere, taxol, 5-fluorouracilo, metotrexato, gemcitabina, cisplatino, carboplatino y clorambucilo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40706910P | 2010-10-27 | 2010-10-27 | |
PCT/CA2011/001179 WO2012097427A1 (en) | 2010-10-27 | 2011-10-26 | Compounds and compositions for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013004832A true MX2013004832A (es) | 2013-05-22 |
MX365807B MX365807B (es) | 2019-06-14 |
Family
ID=46515034
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013004832A MX365807B (es) | 2010-10-27 | 2011-10-26 | Compuestos y composiciones para el tratamiento del cáncer. |
MX2019007010A MX2019007010A (es) | 2010-10-27 | 2013-04-26 | Compuestos y composiciones para el tratamiento del cancer. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019007010A MX2019007010A (es) | 2010-10-27 | 2013-04-26 | Compuestos y composiciones para el tratamiento del cancer. |
Country Status (25)
Country | Link |
---|---|
US (2) | US9114118B2 (es) |
EP (2) | EP2632452B1 (es) |
JP (2) | JP6007186B2 (es) |
KR (2) | KR101821646B1 (es) |
CN (2) | CN105997967B (es) |
AU (2) | AU2011356583C1 (es) |
BR (1) | BR112013010507A2 (es) |
CA (1) | CA2816093C (es) |
CL (1) | CL2013001152A1 (es) |
DK (2) | DK2632452T3 (es) |
EA (2) | EA030038B1 (es) |
ES (2) | ES2703257T3 (es) |
HK (1) | HK1189836A1 (es) |
IL (2) | IL225599A (es) |
MX (2) | MX365807B (es) |
MY (2) | MY184343A (es) |
NZ (1) | NZ610851A (es) |
PH (1) | PH12016502324A1 (es) |
PL (2) | PL3443957T3 (es) |
PT (2) | PT3443957T (es) |
SG (2) | SG10201807622WA (es) |
TR (1) | TR201819987T4 (es) |
TW (2) | TWI620563B (es) |
WO (1) | WO2012097427A1 (es) |
ZA (1) | ZA201303035B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6007186B2 (ja) * | 2010-10-27 | 2016-10-12 | プロメティック・ファーマ・エスエムティ・リミテッドPrometic Pharma Smt Limited | がん治療のための化合物および組成物 |
TWI689489B (zh) * | 2013-03-15 | 2020-04-01 | 英商邊緣生物科技有限公司 | 用於治療肺纖維化、肝纖維化、皮膚纖維化及心臟纖維化之經取代之芳族化合物 |
RU2560702C1 (ru) * | 2014-06-05 | 2015-08-20 | Общество с ограниченной ответственностью "Научно-производственный центр "Амфион" (ООО "НПЦ "Амфион") | Фармацевтическая композиция для применения в онкологии |
WO2016054728A1 (en) * | 2014-10-10 | 2016-04-14 | Prometic Biosciences Inc. | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis |
ES2794782T3 (es) * | 2014-10-10 | 2020-11-19 | Liminal Biosciences Ltd | Compuestos de carboxilato de fenilcetona y composiciones farmacéuticas para la prevención y el tratamiento de la osteoporosis |
AR102634A1 (es) | 2014-11-12 | 2017-03-15 | Prometic Biosciences Inc | Compuestos aromáticos sustituidos y composiciones farmacéuticas para la autorreparación y regeneración del tejido |
CN106267213A (zh) * | 2015-05-27 | 2017-01-04 | 聊城市奥润生物医药科技有限公司 | 环二核苷酸cGAMP在治疗肿瘤联合用药中的应用 |
SG10201913998YA (en) | 2017-07-25 | 2020-03-30 | Taris Biomedical Llc | Methods of treating tumor metastasis |
EP3890717A4 (en) * | 2018-12-05 | 2022-08-24 | Liminal Biosciences Limited | USE OF SODIUM 2-(3-PENTYLPHENYL)ACETATE IN THE TREATMENT OF ALSTRÖM SYNDROME |
US11246945B2 (en) | 2019-06-07 | 2022-02-15 | National Defense Medical Center | Cisplatin-loaded microbubbles, pharmaceutical composition for treatment of cancer, method for preparing pharmaceutical compositions and method for treating cancer |
CN114436822B (zh) * | 2022-01-12 | 2024-04-16 | 厦门稀土材料研究所 | 一枝蒿酮酸和生物碱复盐及其制备方法和用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0268907A3 (en) | 1986-11-19 | 1990-03-21 | Carl Richard Thornfeldt | Treatment of disease conditions relating to hyperactive organelles |
US5605930A (en) * | 1991-10-21 | 1997-02-25 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for treating and preventing pathologies including cancer |
ITMI20012434A1 (it) * | 2001-11-20 | 2003-05-20 | Dompe Spa | Acidi 2-aril-propionici e composizioni farmaceutiche che li contengono |
CN1169768C (zh) * | 2002-04-26 | 2004-10-06 | 中国科学院上海有机化学研究所 | (4-炔基)-芳香酮酸类化合物、合成方法及应用 |
EP1578757B1 (en) * | 2002-12-27 | 2014-10-22 | Janssen Infectious Diseases BVBA | Fluorogenic enzyme substrates and methods of preparation |
WO2005009104A2 (en) * | 2003-07-16 | 2005-02-03 | Ligand Pharmacueticals Incorporated | Benzoic and phenyl acetic acid derivatives as hnf-4 modulators |
WO2005010202A2 (en) * | 2003-07-16 | 2005-02-03 | Ligand Pharmacueticals Incorporated | PHENYL ACETIC ACID DERIVATIVES AS HEPATOCYTE NUCLEAR FACTOR 4α (HNF-4α) MODULATOR COMPOUNDS |
US8198328B2 (en) * | 2004-01-21 | 2012-06-12 | New York University | Treatment of cancer using benzoic acid derivatives |
EP2061452B1 (en) * | 2006-09-01 | 2011-10-26 | Piramal Life Sciences Limited | Anti cancer use of caffeic acid and derivatives |
US20110046050A1 (en) * | 2007-02-08 | 2011-02-24 | Emisphere Technologies, Inc. | Phenylalkylcarboxylic acid delivery agents |
WO2009055932A1 (en) | 2007-11-02 | 2009-05-07 | Prometic Biosciences Inc. | Substituted phenylpropionic acids as stimulators of hematopoiesis and erythropoiesis |
NZ584981A (en) | 2007-11-02 | 2012-05-25 | Prometic Biosciences Inc | Medium-chain length fatty acids and glycerides as nephroprotection agents |
AU2008338204B2 (en) * | 2007-12-19 | 2015-03-05 | Prometic Pharma Smt Limited | Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer |
DK2427417T3 (da) * | 2009-05-04 | 2014-01-20 | Prometic Biosciences Inc | Salte af 3-pentylphenyleddikesyre og farmaceutiske anvendelser deraf |
SG175855A1 (en) * | 2009-05-04 | 2011-12-29 | Prometic Biosciences Inc | Substituted aromatic compounds and pharmaceutical uses thereof |
JP6007186B2 (ja) * | 2010-10-27 | 2016-10-12 | プロメティック・ファーマ・エスエムティ・リミテッドPrometic Pharma Smt Limited | がん治療のための化合物および組成物 |
-
2011
- 2011-10-26 JP JP2013535215A patent/JP6007186B2/ja not_active Expired - Fee Related
- 2011-10-26 BR BR112013010507A patent/BR112013010507A2/pt not_active Application Discontinuation
- 2011-10-26 TR TR2018/19987T patent/TR201819987T4/tr unknown
- 2011-10-26 EA EA201370103A patent/EA030038B1/ru not_active IP Right Cessation
- 2011-10-26 KR KR1020137013238A patent/KR101821646B1/ko active IP Right Grant
- 2011-10-26 MY MYPI2017000606A patent/MY184343A/en unknown
- 2011-10-26 MY MYPI2013001522A patent/MY162420A/en unknown
- 2011-10-26 DK DK11856486.3T patent/DK2632452T3/en active
- 2011-10-26 PT PT181917923T patent/PT3443957T/pt unknown
- 2011-10-26 TW TW106101424A patent/TWI620563B/zh not_active IP Right Cessation
- 2011-10-26 ES ES11856486T patent/ES2703257T3/es active Active
- 2011-10-26 CA CA2816093A patent/CA2816093C/en active Active
- 2011-10-26 ES ES18191792T patent/ES2837599T3/es active Active
- 2011-10-26 TW TW100138943A patent/TWI578983B/zh not_active IP Right Cessation
- 2011-10-26 WO PCT/CA2011/001179 patent/WO2012097427A1/en active Application Filing
- 2011-10-26 US US13/882,355 patent/US9114118B2/en not_active Expired - Fee Related
- 2011-10-26 MX MX2013004832A patent/MX365807B/es active IP Right Grant
- 2011-10-26 EP EP11856486.3A patent/EP2632452B1/en active Active
- 2011-10-26 PT PT11856486T patent/PT2632452T/pt unknown
- 2011-10-26 CN CN201610353298.3A patent/CN105997967B/zh active Active
- 2011-10-26 PL PL18191792T patent/PL3443957T3/pl unknown
- 2011-10-26 AU AU2011356583A patent/AU2011356583C1/en not_active Ceased
- 2011-10-26 SG SG10201807622WA patent/SG10201807622WA/en unknown
- 2011-10-26 PL PL11856486T patent/PL2632452T3/pl unknown
- 2011-10-26 EA EA201791585A patent/EA035494B1/ru not_active IP Right Cessation
- 2011-10-26 NZ NZ610851A patent/NZ610851A/en unknown
- 2011-10-26 CN CN201180052340.3A patent/CN103347509B/zh active Active
- 2011-10-26 DK DK18191792.3T patent/DK3443957T3/da active
- 2011-10-26 KR KR1020187001526A patent/KR101943280B1/ko active IP Right Grant
- 2011-10-26 EP EP18191792.3A patent/EP3443957B1/en active Active
- 2011-10-26 SG SG2013032354A patent/SG189538A1/en unknown
-
2013
- 2013-04-07 IL IL225599A patent/IL225599A/en active IP Right Grant
- 2013-04-25 ZA ZA2013/03035A patent/ZA201303035B/en unknown
- 2013-04-26 CL CL2013001152A patent/CL2013001152A1/es unknown
- 2013-04-26 MX MX2019007010A patent/MX2019007010A/es unknown
-
2014
- 2014-04-01 HK HK14103126.5A patent/HK1189836A1/zh not_active IP Right Cessation
-
2015
- 2015-07-13 US US14/797,957 patent/US9439882B2/en active Active
-
2016
- 2016-03-10 AU AU2016201556A patent/AU2016201556B2/en not_active Ceased
- 2016-08-04 JP JP2016153378A patent/JP6371344B2/ja not_active Expired - Fee Related
- 2016-11-22 PH PH12016502324A patent/PH12016502324A1/en unknown
-
2017
- 2017-03-10 IL IL251083A patent/IL251083B/en active IP Right Grant
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12016502324A1 (en) | Compounds and compositions for the treatment of cancer | |
NZ598890A (en) | Inhibitors of iap | |
PH12017502141A1 (en) | Compounds and their methods of use | |
MX2011011661A (es) | Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750. | |
NZ718826A (en) | Pyrrolobenzodiazepines and conjugates thereof | |
GEP201606555B (en) | Compounds and compositions for modulating egfr activity | |
MA34064B1 (fr) | Compose heterocyclique | |
CL2011000504A1 (es) | Compuestos derivados de piridin-4-il-tiazol-2il-amida 2-amida-pirrolidin-1,2-dicarboxilico, inhibidores de quinasa de fosfatidil-inositol-3; composicion farmaceutica que comprende a uno de los compuestos; y uso de los compuestos en la preparacion de un medicamento para el tratamiento del cancer. | |
MY188911A (en) | Methods of treating bladder cancer | |
MY165624A (en) | N-acylsulfonamide apoptosis promoters | |
BR112014013526A2 (pt) | conjugados de anticorpo-fármaco e compostos, composições e métodos relacionados | |
GEP201706691B (en) | Substituted phthalazin-1 (2h)-one derivatives as selecti- ve inhibitors of poly (adp-ribose) polymerase-1 | |
MX2010013682A (es) | Derivados de 2,4-diamino-l,3,5-triazina triciclicos utiles para el tratamiento del cancer y trastornos mieloproliferativos. | |
MX2012008328A (es) | Derivados de pirazina. | |
EA201390008A1 (ru) | Новые ариламидные производные, обладающие антиандрогенными свойствами | |
WO2014089177A3 (en) | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines | |
WO2010027424A3 (en) | 9-substituted phenanthrene based tylophorine derivatives | |
CO6341625A2 (es) | Derivados de indol como agentes anticáncer | |
MX2015007116A (es) | Nuevos derivados de 1,4-ditiina sustituida y su uso como fungicidas. | |
MX2009009657A (es) | Fluoroquinolonas para el tratamiento, reduccion, mejora, o prevencion de las infecciones provocadas por las bacterias resistentes a los farmacos antibacterianos. | |
TW200800993A (en) | Organic compounds | |
MX2015012600A (es) | Compuestos de tetrahidroisoquinolina-2-il-(quinazolina-4-il) metanona como inhibidores del crecimiento de células cancerígenas. | |
MX2012007253A (es) | Derivados triciclicos y sus usos y composiciones farmaceuticas. | |
MX341492B (es) | Nuevas formas solidas de 1,1-dioxo-4-tiomorfolinil)-[6-[[3(4-fluor ofenil)-5-metil-4-isoxazolil]metoxi]-3-piridinil]-metanona. | |
MX2011008069A (es) | Uso de inhibidores de topoisomerasa i para tratar el cancer. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights |
Owner name: PROMETIC PHARMA SMT LIMITED |
|
FG | Grant or registration |