MX2013004207A - Dispositivo de prueba. - Google Patents

Dispositivo de prueba.

Info

Publication number
MX2013004207A
MX2013004207A MX2013004207A MX2013004207A MX2013004207A MX 2013004207 A MX2013004207 A MX 2013004207A MX 2013004207 A MX2013004207 A MX 2013004207A MX 2013004207 A MX2013004207 A MX 2013004207A MX 2013004207 A MX2013004207 A MX 2013004207A
Authority
MX
Mexico
Prior art keywords
binding partners
capillary tube
region
analyte
binding
Prior art date
Application number
MX2013004207A
Other languages
English (en)
Other versions
MX347049B (es
Inventor
Stephen John Minter
Georgios Patsos
Original Assignee
Moorlodge Biotech Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moorlodge Biotech Ventures Ltd filed Critical Moorlodge Biotech Ventures Ltd
Publication of MX2013004207A publication Critical patent/MX2013004207A/es
Publication of MX347049B publication Critical patent/MX347049B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Un dispositivo de ensayo (1) para determinar la presencia y/o la cantidad de un analito presente o potencialmente presente en una muestra líquida comprende: (i) un tubo capilar (2) que tiene una región corriente arriba (3) en la cual se introduce la muestra a ensayar para su transferencia por acción capilar a lo largo del tubo capilar a una región corriente abajo del mismo; (ii) un conjunto de primeros participantes de unión (5) inmovilizados dentro del tubo capilar (2), en que dichos primeros participantes de unión (5) son capaces de unirse específicamente al aflauto; (iii) un conjunto de segundos participantes de unión (6) unidos desplazablemente a una fracción de dichos primeros participantes de unión (5), con lo cual hay primeros participantes de unión (5) libres, inmovilizados dentro del tubo capilar, dichos segundos participantes de unión (6) tienen una etiqueta y son desplazables a partir de los primeros participantes de unión (5) por el analito a detectar; y (iv) un región de detección está adaptada para generar una señal detectable de la etiqueta en los segundos participantes de unión (6) que se han transferido a la región corriente abajo.
MX2013004207A 2010-10-15 2011-10-17 Dispositivo de prueba. MX347049B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1017447.2A GB201017447D0 (en) 2010-10-15 2010-10-15 Assay device
PCT/GB2011/001487 WO2012049465A1 (en) 2010-10-15 2011-10-17 Assay device

Publications (2)

Publication Number Publication Date
MX2013004207A true MX2013004207A (es) 2013-08-27
MX347049B MX347049B (es) 2017-04-07

Family

ID=43333888

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013004207A MX347049B (es) 2010-10-15 2011-10-17 Dispositivo de prueba.

Country Status (15)

Country Link
US (1) US9696303B2 (es)
EP (1) EP2627784A1 (es)
JP (1) JP6046627B2 (es)
CN (1) CN103261441B (es)
AP (1) AP2013006864A0 (es)
AU (1) AU2011315244B8 (es)
BR (1) BR112013009202A2 (es)
CA (1) CA2818782A1 (es)
EA (1) EA028778B1 (es)
GB (1) GB201017447D0 (es)
MX (1) MX347049B (es)
NZ (1) NZ610607A (es)
SG (2) SG189411A1 (es)
WO (1) WO2012049465A1 (es)
ZA (1) ZA201303504B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015085262A1 (en) * 2013-12-05 2015-06-11 The General Hospital Corporation Modular instrumentation for analyzing biological fluids
CN103983769B (zh) * 2014-03-25 2015-11-18 中国海洋大学 一种纳米金免疫层析毛细管的制备方法
CN103983749B (zh) * 2014-03-25 2015-06-17 中国海洋大学 一种水产品中小清蛋白的毛细管免疫层析快速检测方法
GB201415674D0 (en) 2014-09-04 2014-10-22 Moorlodge Biotech Ventures Ltd Nucleic acid analysis
CN112326641A (zh) * 2020-07-29 2021-02-05 浙江今复康生物科技有限公司 一种从咳出样品中快速鉴别痰液成分的方法及试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2186852C2 (ru) 1991-12-24 2002-08-10 Тепнел Медикал Лимитед Способ выполнения манипуляции с последовательностью нуклеиновой кислоты, устройство для проведения манипуляций на последовательности нуклеиновой кислоты, проточный сосуд, твердый носитель для иммобилизации последовательности нуклеиновой кислоты, твердый носитель, способ получения носителя для иммобилизации последовательности нуклеиновой кислоты
GB9127415D0 (en) 1991-12-24 1992-02-19 Swordfish Int Ltd Solid support bound detection and diagnostic system
AU7563294A (en) 1993-08-24 1995-03-21 Metrika Laboratories, Inc. Novel disposable electronic assay device
US6750031B1 (en) 1996-01-11 2004-06-15 The United States Of America As Represented By The Secretary Of The Navy Displacement assay on a porous membrane
US6020209A (en) * 1997-04-28 2000-02-01 The United States Of America As Represented By The Secretary Of The Navy Microcapillary-based flow-through immunosensor and displacement immunoassay using the same
GB9825992D0 (en) 1998-11-28 1999-01-20 Moorlodge Biotech Ventures Lim Electrochemical sensor
US20040005582A1 (en) 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
GB0306098D0 (en) 2003-03-18 2003-04-23 Platform Diagnostics Group Ltd Sample testing device
CA2586515A1 (en) * 2003-11-05 2005-05-26 Exact Sciences Corporation Repetitive reversed-field affinity electrophoresis and uses therefor
GB0423885D0 (en) 2004-10-28 2004-12-01 Platform Diagnostics Ltd Blood analysis
WO2007054714A2 (en) 2005-11-12 2007-05-18 Platform Diagnostics Limited Agglutination assay
GB2432211B (en) 2005-11-12 2009-04-22 Platform Diagnostics Ltd Agglutination based assay system
ES2288429B2 (es) 2006-06-28 2009-10-13 Universidad Politecnica De Valencia Procedimiento de modificacion quimica de superficies polimericas destinadas a la inmovilizacion de moleculas.
GB2443694B (en) 2006-11-10 2011-09-14 Platform Diagnostics Ltd Analyte saturation assay, methods and kits and devices

Also Published As

Publication number Publication date
ZA201303504B (en) 2014-07-30
SG189411A1 (en) 2013-05-31
JP2013541008A (ja) 2013-11-07
AU2011315244B8 (en) 2017-03-16
CA2818782A1 (en) 2012-04-19
WO2012049465A1 (en) 2012-04-19
WO2012049465A8 (en) 2012-05-24
EA028778B1 (ru) 2017-12-29
US20130280699A1 (en) 2013-10-24
AP2013006864A0 (en) 2013-05-31
EP2627784A1 (en) 2013-08-21
AU2011315244A1 (en) 2013-06-06
MX347049B (es) 2017-04-07
US9696303B2 (en) 2017-07-04
CN103261441A (zh) 2013-08-21
EA201390561A1 (ru) 2014-01-30
NZ610607A (en) 2015-05-29
JP6046627B2 (ja) 2016-12-21
AU2011315244B2 (en) 2016-11-17
SG10201600322YA (en) 2016-02-26
GB201017447D0 (en) 2010-12-01
AU2011315244A8 (en) 2017-03-16
CN103261441B (zh) 2016-07-06
BR112013009202A2 (pt) 2018-05-08

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