WO2011008030A3 - 핵산 검출용 크로마토그래피 시스템 - Google Patents

핵산 검출용 크로마토그래피 시스템 Download PDF

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Publication number
WO2011008030A3
WO2011008030A3 PCT/KR2010/004598 KR2010004598W WO2011008030A3 WO 2011008030 A3 WO2011008030 A3 WO 2011008030A3 KR 2010004598 W KR2010004598 W KR 2010004598W WO 2011008030 A3 WO2011008030 A3 WO 2011008030A3
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Prior art keywords
nucleic acid
strip
acid detection
chromatographic system
present
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PCT/KR2010/004598
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English (en)
French (fr)
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WO2011008030A2 (ko
Inventor
최의열
남기봉
정동석
김성중
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바디텍메드 주식회사
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Application filed by 바디텍메드 주식회사 filed Critical 바디텍메드 주식회사
Priority to US13/384,190 priority Critical patent/US20120149008A1/en
Priority to CN2010800361601A priority patent/CN102471807A/zh
Priority to EP10800041A priority patent/EP2455487A4/en
Publication of WO2011008030A2 publication Critical patent/WO2011008030A2/ko
Publication of WO2011008030A3 publication Critical patent/WO2011008030A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/625—Detection means characterised by use of a special device being a nucleic acid test strip device, e.g. dipsticks, strips, tapes, CD plates

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

본 발명은 측방이동 전개 방식 및 핵산의 서열 특이적 교잡반응의 원리를 기본으로 하는, 분석시료 중의 핵산 검출용 스트립, 상기 스트립을 포함하는 핵산 검출 시스템 및 상기 스트립을 이용한 특정 핵산 검출 방법에 관한 것이다. 본 발명의 스트립, 시스템 및 방법은 사용의 용이성은 물론 검출 민감도 및 특이도가 매우 높아 소량의 핵산을 이용해서도 정확하며 신속한 분석은 가능하게 한다.
PCT/KR2010/004598 2009-07-17 2010-07-15 핵산 검출용 크로마토그래피 시스템 WO2011008030A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/384,190 US20120149008A1 (en) 2009-07-17 2010-07-15 Chromatographic system for nucleic acid detection
CN2010800361601A CN102471807A (zh) 2009-07-17 2010-07-15 用于核酸检测的层析系统
EP10800041A EP2455487A4 (en) 2009-07-17 2010-07-15 CHROMATOGRAPHIC SYSTEM FOR THE DETECTION OF NUCLEIC ACIDS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090065275A KR101115014B1 (ko) 2009-07-17 2009-07-17 핵산 검출용 크로마토그래피 시스템
KR10-2009-0065275 2009-07-17

Publications (2)

Publication Number Publication Date
WO2011008030A2 WO2011008030A2 (ko) 2011-01-20
WO2011008030A3 true WO2011008030A3 (ko) 2011-05-19

Family

ID=43449976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/004598 WO2011008030A2 (ko) 2009-07-17 2010-07-15 핵산 검출용 크로마토그래피 시스템

Country Status (5)

Country Link
US (1) US20120149008A1 (ko)
EP (1) EP2455487A4 (ko)
KR (1) KR101115014B1 (ko)
CN (1) CN102471807A (ko)
WO (1) WO2011008030A2 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101409263B1 (ko) 2012-10-16 2014-07-02 바디텍메드 주식회사 서브패드를 구비한 측방유동 분석용 스트립 및 이에 사용되는 측방유동 분석용 카트리지
WO2015072718A1 (ko) 2013-11-12 2015-05-21 바디텍메드 주식회사 일체화된 반응 및 검출 수단을 구비하는 멀티웰 큐베트
US10393738B2 (en) 2013-11-12 2019-08-27 Boditech Med Inc. Multi-well cuvette provided with integrated reaction and detection means
CN104614524A (zh) * 2015-03-01 2015-05-13 河南省科隆医疗器械有限公司 一种宫颈癌hpv快速检测装置的试纸条
US10871474B2 (en) 2015-05-14 2020-12-22 Boditech Med Inc. System and method for analyzing biological fluid in multiple cuvettes
KR101811786B1 (ko) 2015-05-14 2017-12-22 바디텍메드(주) 일체화된 반응 및 검출 수단을 구비한 시험 장치에 사용되는 스테이션
GB201515355D0 (en) 2015-08-28 2015-10-14 Ge Healthcare Ltd A method and kit for analyte detection
CN105259151B (zh) * 2015-11-02 2018-07-31 深圳市锦瑞生物科技有限公司 一种荧光检测系统及仪器
CN111647682A (zh) * 2019-03-04 2020-09-11 深圳市第二人民医院 基于纳米酶的hpv16核酸检测试纸条
WO2022114941A1 (en) * 2020-11-24 2022-06-02 Autonomous Organization Of Education "Nazarbayev University" Method for detecting hpv16 and in vitro diagnostic device for detection
CN115792241B (zh) * 2022-11-23 2024-07-23 弗雷米德生物医药技术（天津）有限公司 一种宫颈癌e7蛋白检测抗体抗原的检测盒及其检测方法

Citations (4)

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US20050014154A1 (en) * 2001-11-05 2005-01-20 Michael Weizenegger Method in the form of a dry rapid test for detecting nucleic acids
JP2006201062A (ja) * 2005-01-21 2006-08-03 Kainosu:Kk 核酸の検出あるいは定量方法
KR20090006999A (ko) * 2007-07-13 2009-01-16 바디텍메드 주식회사 당화헤모글로빈의 정량분석을 위한 시스템 및 이를 이용한당화헤모글로빈 측정 방법

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US20050014154A1 (en) * 2001-11-05 2005-01-20 Michael Weizenegger Method in the form of a dry rapid test for detecting nucleic acids
KR20030003181A (ko) * 2002-12-02 2003-01-09 김희태 멤브레인 크로마토그래프 기법에 의한 핵산 검출 방법 및이를 위한 킷트
JP2006201062A (ja) * 2005-01-21 2006-08-03 Kainosu:Kk 核酸の検出あるいは定量方法
KR20090006999A (ko) * 2007-07-13 2009-01-16 바디텍메드 주식회사 당화헤모글로빈의 정량분석을 위한 시스템 및 이를 이용한당화헤모글로빈 측정 방법

Also Published As

Publication number Publication date
US20120149008A1 (en) 2012-06-14
CN102471807A (zh) 2012-05-23
EP2455487A2 (en) 2012-05-23
KR20110007699A (ko) 2011-01-25
EP2455487A4 (en) 2013-03-13
KR101115014B1 (ko) 2012-03-06
WO2011008030A2 (ko) 2011-01-20

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