EA201390561A1 - Аналитическое устройство - Google Patents

Аналитическое устройство

Info

Publication number
EA201390561A1
EA201390561A1 EA201390561A EA201390561A EA201390561A1 EA 201390561 A1 EA201390561 A1 EA 201390561A1 EA 201390561 A EA201390561 A EA 201390561A EA 201390561 A EA201390561 A EA 201390561A EA 201390561 A1 EA201390561 A1 EA 201390561A1
Authority
EA
Eurasian Patent Office
Prior art keywords
binding
partners
capillary tube
sample
transferred
Prior art date
Application number
EA201390561A
Other languages
English (en)
Other versions
EA028778B1 (ru
Inventor
Стефен Джон Минтер
Георгиос Патсос
Original Assignee
Мурлодж Байотек Венчерз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мурлодж Байотек Венчерз Лимитед filed Critical Мурлодж Байотек Венчерз Лимитед
Publication of EA201390561A1 publication Critical patent/EA201390561A1/ru
Publication of EA028778B1 publication Critical patent/EA028778B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Аналитическое устройство (1) для определения наличия и/или количества аналита, присутствующего или присутствие которого потенциально возможно в жидкой пробе, содержит: (i) капиллярную трубку (2), имеющую ближнюю область (3), в которую вводится подвергаемая анализу проба для переноса за счет капиллярных сил вдоль капиллярной трубки в ее дальнюю область; (ii) набор первых партнеров (5) связывания, иммобилизованных в капиллярной трубке (2), при этом указанные первые партнеры (5) связывания способны специфически связываться с аналитом; (iii) набор вторых партнеров (6) связывания, связанных с частью указанных первых партнеров (5) связывания с возможностью перемещения, благодаря чему существуют свободные первые партнеры (5) связывания, иммобилизованные в капиллярной трубке, при этом указанные вторые партнеры (6) связывания имеют метку и могут перемещаться от первых партнеров (5) связывания аналитом, который требуется обнаружить; а также (iv) область (4) детекции для пробы, которая была перенесена в указанную дальнюю область указанной капиллярной трубки, при этом указанная область детекции выполнена с возможностью генерирования различимого сигнала от метки на перемещенных вторых партнерах (6) связывания, перенесенных в дальнюю область.
EA201390561A 2010-10-15 2011-10-17 Аналитическое устройство EA028778B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1017447.2 2010-10-15
GBGB1017447.2A GB201017447D0 (en) 2010-10-15 2010-10-15 Assay device
PCT/GB2011/001487 WO2012049465A1 (en) 2010-10-15 2011-10-17 Assay device

Publications (2)

Publication Number Publication Date
EA201390561A1 true EA201390561A1 (ru) 2014-01-30
EA028778B1 EA028778B1 (ru) 2017-12-29

Family

ID=43333888

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390561A EA028778B1 (ru) 2010-10-15 2011-10-17 Аналитическое устройство

Country Status (15)

Country Link
US (1) US9696303B2 (ru)
EP (1) EP2627784A1 (ru)
JP (1) JP6046627B2 (ru)
CN (1) CN103261441B (ru)
AP (1) AP2013006864A0 (ru)
AU (1) AU2011315244B8 (ru)
BR (1) BR112013009202A2 (ru)
CA (1) CA2818782A1 (ru)
EA (1) EA028778B1 (ru)
GB (1) GB201017447D0 (ru)
MX (1) MX347049B (ru)
NZ (1) NZ610607A (ru)
SG (2) SG189411A1 (ru)
WO (1) WO2012049465A1 (ru)
ZA (1) ZA201303504B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10220387B2 (en) 2013-12-05 2019-03-05 The General Hospital Corporation Modular instrumentation for analyzing biological fluids
CN103983769B (zh) * 2014-03-25 2015-11-18 中国海洋大学 一种纳米金免疫层析毛细管的制备方法
CN103983749B (zh) * 2014-03-25 2015-06-17 中国海洋大学 一种水产品中小清蛋白的毛细管免疫层析快速检测方法
GB201415674D0 (en) 2014-09-04 2014-10-22 Moorlodge Biotech Ventures Ltd Nucleic acid analysis
CN112326641B (zh) * 2020-07-29 2024-07-05 浙江今复康生物科技有限公司 一种从咳出样品中快速鉴别痰液成分的方法及试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69231003T2 (de) * 1991-12-24 2000-10-19 Tepnel Medical Ltd., Manchester Manipulation von nukleinsäuresequenzen
GB9127415D0 (en) 1991-12-24 1992-02-19 Swordfish Int Ltd Solid support bound detection and diagnostic system
WO1995006240A1 (en) 1993-08-24 1995-03-02 Metrika Laboratories, Inc. Novel disposable electronic assay device
US6750031B1 (en) * 1996-01-11 2004-06-15 The United States Of America As Represented By The Secretary Of The Navy Displacement assay on a porous membrane
US6020209A (en) * 1997-04-28 2000-02-01 The United States Of America As Represented By The Secretary Of The Navy Microcapillary-based flow-through immunosensor and displacement immunoassay using the same
GB9825992D0 (en) 1998-11-28 1999-01-20 Moorlodge Biotech Ventures Lim Electrochemical sensor
US20040005582A1 (en) * 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
GB0306098D0 (en) 2003-03-18 2003-04-23 Platform Diagnostics Group Ltd Sample testing device
EP1685395A2 (en) * 2003-11-05 2006-08-02 EXACT Sciences Corporation Repetitive reversed-field affinity electrophoresis and uses therefor
GB0423885D0 (en) 2004-10-28 2004-12-01 Platform Diagnostics Ltd Blood analysis
GB2432211B (en) 2005-11-12 2009-04-22 Platform Diagnostics Ltd Agglutination based assay system
CA2629290C (en) 2005-11-12 2014-05-06 Carolyn Jennifer Ruddell Agglutination assay
ES2288429B2 (es) 2006-06-28 2009-10-13 Universidad Politecnica De Valencia Procedimiento de modificacion quimica de superficies polimericas destinadas a la inmovilizacion de moleculas.
GB2443694B (en) 2006-11-10 2011-09-14 Platform Diagnostics Ltd Analyte saturation assay, methods and kits and devices

Also Published As

Publication number Publication date
MX347049B (es) 2017-04-07
WO2012049465A1 (en) 2012-04-19
NZ610607A (en) 2015-05-29
JP2013541008A (ja) 2013-11-07
ZA201303504B (en) 2014-07-30
AU2011315244A1 (en) 2013-06-06
AU2011315244A8 (en) 2017-03-16
SG189411A1 (en) 2013-05-31
MX2013004207A (es) 2013-08-27
CN103261441A (zh) 2013-08-21
EP2627784A1 (en) 2013-08-21
BR112013009202A2 (pt) 2018-05-08
JP6046627B2 (ja) 2016-12-21
WO2012049465A8 (en) 2012-05-24
US20130280699A1 (en) 2013-10-24
AP2013006864A0 (en) 2013-05-31
EA028778B1 (ru) 2017-12-29
GB201017447D0 (en) 2010-12-01
AU2011315244B8 (en) 2017-03-16
CN103261441B (zh) 2016-07-06
US9696303B2 (en) 2017-07-04
CA2818782A1 (en) 2012-04-19
AU2011315244B2 (en) 2016-11-17
SG10201600322YA (en) 2016-02-26

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU