MX2013002384A - Compuestos quinazolina y metodos para utilizarlos. - Google Patents
Compuestos quinazolina y metodos para utilizarlos.Info
- Publication number
- MX2013002384A MX2013002384A MX2013002384A MX2013002384A MX2013002384A MX 2013002384 A MX2013002384 A MX 2013002384A MX 2013002384 A MX2013002384 A MX 2013002384A MX 2013002384 A MX2013002384 A MX 2013002384A MX 2013002384 A MX2013002384 A MX 2013002384A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- compounds
- kinase
- quinazoline compounds
- mediated diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
En la presente se proporcionan los compuestos quinazolina de fórmula (I) (Ver Formula) para el tratamiento de las enfermedades en las que interviene JAK cinasa, así como JAK2 cinasa, JAK3 cinasa o TYK2 cinasa. También se proporcionan las composiciones farmacéuticas que contienen los compuestos, y los métodos de uso de los compuestos y las composiciones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37930910P | 2010-09-01 | 2010-09-01 | |
PCT/US2011/049950 WO2012030948A1 (en) | 2010-09-01 | 2011-08-31 | Quinazoline compounds and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2013002384A true MX2013002384A (es) | 2013-07-05 |
Family
ID=44645826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013002384A MX2013002384A (es) | 2010-09-01 | 2011-08-31 | Compuestos quinazolina y metodos para utilizarlos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US8633207B2 (es) |
EP (1) | EP2611789A1 (es) |
JP (1) | JP5901634B2 (es) |
KR (1) | KR20130102060A (es) |
CN (1) | CN103298805A (es) |
AU (1) | AU2011296024B2 (es) |
CA (1) | CA2810024A1 (es) |
MX (1) | MX2013002384A (es) |
WO (1) | WO2012030948A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013135674A1 (en) * | 2012-03-12 | 2013-09-19 | Syngenta Participations Ag | Insecticidal 2-aryl-acetamide compounds |
CN103301133B (zh) * | 2012-12-11 | 2014-09-17 | 中国药科大学 | 一类氨基喹唑啉表皮生长因子受体拮抗剂的抗肿瘤治疗用途 |
WO2016049532A1 (en) | 2014-09-26 | 2016-03-31 | Unitract Syringe Pty Ltd | Sequential chamber drug delivery pumps for drug mixing and delivery |
JP2018135268A (ja) * | 2015-06-05 | 2018-08-30 | 大日本住友製薬株式会社 | 新規ヘテロアリールアミノ−3−ピラゾール誘導体およびその薬理学上許容される塩 |
CN105503837B (zh) * | 2015-12-31 | 2018-06-29 | 中山大学 | 具有Aurora激酶抑制活性的取代喹唑啉类衍生物及其应用 |
US20220235013A1 (en) | 2017-03-21 | 2022-07-28 | Bayer Pharma Aktiengesellschaft | 2-methyl-quinazolines |
CN107375308B (zh) * | 2017-09-04 | 2021-02-12 | 四川美大康药业股份有限公司 | 毛蕊花糖苷在制备预防或治疗肾小球足细胞损伤型肾脏疾病的药物中的用途 |
EP4214204A1 (en) | 2020-09-18 | 2023-07-26 | Bayer Aktiengesellschaft | Pyrido[2,3-d]pyrimidin-4-amines as sos1 inhibitors |
EP4074317A1 (en) | 2021-04-14 | 2022-10-19 | Bayer AG | Phosphorus derivatives as novel sos1 inhibitors |
WO2024056782A1 (en) | 2022-09-16 | 2024-03-21 | Bayer Aktiengesellschaft | Sulfone-substituted pyrido[3,4-d]pyrimidine derivatives for the treatment of cancer |
WO2024079252A1 (en) | 2022-10-13 | 2024-04-18 | Bayer Aktiengesellschaft | Sos1 inhibitors |
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-
2011
- 2011-08-31 CN CN2011800527654A patent/CN103298805A/zh active Pending
- 2011-08-31 KR KR1020137007907A patent/KR20130102060A/ko not_active Application Discontinuation
- 2011-08-31 JP JP2013527261A patent/JP5901634B2/ja not_active Expired - Fee Related
- 2011-08-31 EP EP11755510.2A patent/EP2611789A1/en not_active Withdrawn
- 2011-08-31 US US13/222,937 patent/US8633207B2/en not_active Expired - Fee Related
- 2011-08-31 AU AU2011296024A patent/AU2011296024B2/en not_active Ceased
- 2011-08-31 CA CA2810024A patent/CA2810024A1/en not_active Abandoned
- 2011-08-31 WO PCT/US2011/049950 patent/WO2012030948A1/en active Application Filing
- 2011-08-31 MX MX2013002384A patent/MX2013002384A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2011296024B2 (en) | 2015-05-28 |
CA2810024A1 (en) | 2012-03-08 |
KR20130102060A (ko) | 2013-09-16 |
CN103298805A (zh) | 2013-09-11 |
EP2611789A1 (en) | 2013-07-10 |
US8633207B2 (en) | 2014-01-21 |
AU2011296024A1 (en) | 2013-03-28 |
WO2012030948A1 (en) | 2012-03-08 |
US20120053174A1 (en) | 2012-03-01 |
JP5901634B2 (ja) | 2016-04-13 |
JP2013538811A (ja) | 2013-10-17 |
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