MX2012003914A - Metodo para la fabricacion de acidos aminohidroxi difosfonicos. - Google Patents

Metodo para la fabricacion de acidos aminohidroxi difosfonicos.

Info

Publication number
MX2012003914A
MX2012003914A MX2012003914A MX2012003914A MX2012003914A MX 2012003914 A MX2012003914 A MX 2012003914A MX 2012003914 A MX2012003914 A MX 2012003914A MX 2012003914 A MX2012003914 A MX 2012003914A MX 2012003914 A MX2012003914 A MX 2012003914A
Authority
MX
Mexico
Prior art keywords
sub
diphosphonic acids
manufacture
aminocarboxylic acid
amino
Prior art date
Application number
MX2012003914A
Other languages
English (en)
Inventor
Patrick Notte
David Lemin
Samuel Corentin Cogels
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of MX2012003914A publication Critical patent/MX2012003914A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La tecnología de esta invención concierne a un método para la fabricación de ácidos hidroxi difosfónicos que contienen una porción amino; el método implica específicamente hacer reaccionar un P4O6 líquido con un ácido aminocarboxílico en la presencia de un ácido sulfónico; el ácido aminocarboxílico es seleccionado de 3 compuestos estructuralmente diferentes: los ácidos aminohidroxi difosfónicos pueden ser sintetizados con alta selectividad y pureza y los materiales de partida sin reaccionar pueden ser recirculados conveniente y fácilmente.
MX2012003914A 2009-10-02 2010-10-04 Metodo para la fabricacion de acidos aminohidroxi difosfonicos. MX2012003914A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09172040 2009-10-02
PCT/EP2010/064755 WO2011039378A1 (en) 2009-10-02 2010-10-04 Method for the manufacture of aminohydroxy diphosphonic acids

Publications (1)

Publication Number Publication Date
MX2012003914A true MX2012003914A (es) 2012-05-08

Family

ID=41268330

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012003914A MX2012003914A (es) 2009-10-02 2010-10-04 Metodo para la fabricacion de acidos aminohidroxi difosfonicos.

Country Status (12)

Country Link
US (1) US8779135B2 (es)
EP (1) EP2483283B1 (es)
JP (2) JP5748759B2 (es)
CN (1) CN102639545B (es)
AU (1) AU2010302597B2 (es)
BR (1) BR112012007554B1 (es)
CA (1) CA2775004A1 (es)
ES (1) ES2533799T3 (es)
MX (1) MX2012003914A (es)
PL (1) PL2483283T3 (es)
RU (1) RU2553822C2 (es)
WO (1) WO2011039378A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012007554B1 (pt) * 2009-10-02 2018-09-04 Monsanto Technology Llc método para a fabricação de ácidos amino hidróxi disfofônico
ES2609488T3 (es) 2012-07-17 2017-04-20 Straitmark Holding Ag Método para la síntesis de N-(fosfonometil)glicina
BR112015000993B1 (pt) * 2012-07-17 2020-04-28 Monsanto Technology Llc método para a síntese de um ácido alfaaminoalquileno fosfônico ou de um éster do mesmo
RU2694047C2 (ru) 2012-07-17 2019-07-09 МОНСАНТО ТЕКНОЛОДЖИ ЭлЭлСи Способ синтеза аминоалкиленфосфоновой кислоты
IN2015DN01082A (es) * 2012-07-17 2015-06-26 Straitmark Holding Ag
JP2016534077A (ja) * 2013-10-25 2016-11-04 ストライトマーク ホールディング アクツィエンゲゼルシャフトＳｔｒａｉｔｍａｒｋ Ｈｏｌｄｉｎｇ ＡＧ アルカン−１−ヒドロキシ−１，１−ジホスホン酸の合成方法
RU2016118638A (ru) * 2013-10-25 2017-11-28 Страйтмарк Холдинг Аг Способ синтеза этан-1-гидрокси-1,1-дифосфоновой кислоты
CN106179235A (zh) * 2016-08-29 2016-12-07 江苏海普功能材料有限公司 一种除化学镍吸附剂及其制备方法
CN107655871A (zh) * 2017-09-12 2018-02-02 重庆医科大学 一种阿仑膦酸钠的高灵敏宽检测范围荧光检测新方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE235068C (es) 1910-03-24 1911-05-31
DE3016289A1 (de) 1980-04-28 1981-10-29 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren
DD222030A1 (de) 1983-10-27 1985-05-08 Adw Ddr Verfahren zur herstellung von amino-1-hydroxy-alkan-1,1-bisphosphonsaeuren
DD235068A1 (de) * 1985-03-06 1986-04-23 Piesteritz Agrochemie Verfahren zur herstellung von oligomeren, c-nh-c-verknuepften amino-1-hydroxy-alkan-1,1-bisphosphonsaeuren und ihren monomeren
US5019651A (en) 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
TW257765B (es) 1993-08-25 1995-09-21 Merck & Co Inc
CA2197267C (en) 1997-02-11 2000-02-08 Yong Tao Process for the production of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
ES2153794B1 (es) 1999-08-06 2001-10-16 Medichem Sa Procedimiento para la obtencion del acido 4-amino-1-hidroxibutiliden-1,1-bisfosfonico y de su sal monosodica trihidratada.
PT1914237E (pt) * 1999-12-03 2014-09-09 Univ California Compostos antivíricos de éster fosfonato
PE20011065A1 (es) 2000-02-01 2001-11-21 Procter & Gamble Proceso para fabricar bisfosfonatos geminales
HUP0300227A2 (hu) * 2003-01-28 2004-09-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás nagy tisztaságú 2-szubsztituált -1-(hidroxi-etilidén)-1,1-biszfoszfonsavak és sóik előállítására
CL2008003539A1 (es) * 2007-11-28 2009-07-03 Procedimiento para la produccion de p4o6 que comprende mezclar o2 o una mezcla de o2 mas un gas inerte y fosforo en donde el producto obtenido se mantiene dentro de una unidad de reaccion a una temperatura entre los 1600 y 2000 k durante por lo menos 1 segundo.
BR112012007554B1 (pt) * 2009-10-02 2018-09-04 Monsanto Technology Llc método para a fabricação de ácidos amino hidróxi disfofônico

Also Published As

Publication number Publication date
ES2533799T3 (es) 2015-04-14
WO2011039378A1 (en) 2011-04-07
RU2553822C2 (ru) 2015-06-20
AU2010302597B2 (en) 2016-06-09
US20120245354A1 (en) 2012-09-27
JP5748759B2 (ja) 2015-07-15
EP2483283B1 (en) 2015-01-07
PL2483283T3 (pl) 2015-06-30
JP2013506641A (ja) 2013-02-28
RU2012114728A (ru) 2013-11-10
JP5978336B2 (ja) 2016-08-24
BR112012007554B1 (pt) 2018-09-04
CN102639545A (zh) 2012-08-15
EP2483283A1 (en) 2012-08-08
CN102639545B (zh) 2016-08-03
US8779135B2 (en) 2014-07-15
JP2015131836A (ja) 2015-07-23
BR112012007554A2 (pt) 2016-11-29
CA2775004A1 (en) 2011-04-07
AU2010302597A1 (en) 2012-04-12

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