MX2011007754A - Composicion farmaceutica finamente pulverizada. - Google Patents

Composicion farmaceutica finamente pulverizada.

Info

Publication number
MX2011007754A
MX2011007754A MX2011007754A MX2011007754A MX2011007754A MX 2011007754 A MX2011007754 A MX 2011007754A MX 2011007754 A MX2011007754 A MX 2011007754A MX 2011007754 A MX2011007754 A MX 2011007754A MX 2011007754 A MX2011007754 A MX 2011007754A
Authority
MX
Mexico
Prior art keywords
finely pulverized
pharmaceutical composition
composition
poorly soluble
medicinal substance
Prior art date
Application number
MX2011007754A
Other languages
English (en)
Inventor
Shigeru Chikase
Dai Kawada
Original Assignee
Meiji Seika Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Pharma Co Ltd filed Critical Meiji Seika Pharma Co Ltd
Publication of MX2011007754A publication Critical patent/MX2011007754A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe una composición que contiene una sustancia medicinal pobremente soluble y que tiene absorción oral mejorada y un método para producir la composición. Se describe específicamente una composición finamente pulverizada que contiene una sustancia medicinal pobremente soluble tal como 22ß-metoxiolean-l2-eno--3ß,2 4(4ß)-diol y un agente tensioactivo hidrofílico. También se describe específicamente un método para producir una composición finamente pulverizada, que se caracteriza porque una sustancia medicinal poco soluble y una gente tensioactivo hidrofílico se dispersan primero en un solvente y luego se pulverizan por un homogeneizador de alta presión.
MX2011007754A 2009-01-30 2010-01-29 Composicion farmaceutica finamente pulverizada. MX2011007754A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009019771 2009-01-30
PCT/JP2010/051262 WO2010087447A1 (ja) 2009-01-30 2010-01-29 微粉砕医薬組成物

Publications (1)

Publication Number Publication Date
MX2011007754A true MX2011007754A (es) 2011-08-12

Family

ID=42395702

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007754A MX2011007754A (es) 2009-01-30 2010-01-29 Composicion farmaceutica finamente pulverizada.

Country Status (12)

Country Link
US (1) US20110294901A1 (es)
EP (1) EP2392354A4 (es)
JP (1) JPWO2010087447A1 (es)
KR (1) KR20110117145A (es)
CN (1) CN102365098A (es)
AU (1) AU2010208880A1 (es)
BR (1) BRPI1007557A2 (es)
CA (1) CA2751236A1 (es)
MX (1) MX2011007754A (es)
RU (1) RU2011135958A (es)
SG (1) SG173158A1 (es)
WO (1) WO2010087447A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108567803B (zh) * 2018-06-29 2021-03-02 江西济民可信药业有限公司 一种金水宝金胶囊的制备方法
WO2024058099A1 (ja) * 2022-09-12 2024-03-21 住友ファーマ株式会社 懸濁用顆粒

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
CN1083483C (zh) * 1994-09-12 2002-04-24 生态实验室股份有限公司 用于塑料器皿的漂清助剂
US5510118A (en) * 1995-02-14 1996-04-23 Nanosystems Llc Process for preparing therapeutic compositions containing nanoparticles
DK0879824T3 (da) 1995-07-07 2004-08-30 Meiji Seika Kaisha Triterpenderivater og middel mod leversygdom
JP3384967B2 (ja) * 1997-08-07 2003-03-10 花王株式会社 脂肪酸類からの飽和脂肪酸の低減方法
WO2002000196A2 (en) * 2000-06-28 2002-01-03 Smithkline Beecham P.L.C. Wet milling process
US20030224058A1 (en) * 2002-05-24 2003-12-04 Elan Pharma International, Ltd. Nanoparticulate fibrate formulations
JP2004099442A (ja) 2002-09-04 2004-04-02 Nisshin Pharma Inc 難溶性薬物含有製剤およびその製造方法
EP1587499A1 (en) * 2003-01-31 2005-10-26 Elan Pharma International Limited Nanoparticulate topiramate formulations
US8623405B2 (en) * 2005-01-28 2014-01-07 Takeda Pharmaceutical Company Limited Finely divided composition containing poorly water soluble substance
CN101646686A (zh) * 2007-03-20 2010-02-10 明治制果株式会社 铁过剩症的预防或治疗剂

Also Published As

Publication number Publication date
WO2010087447A1 (ja) 2010-08-05
CA2751236A1 (en) 2010-08-05
CN102365098A (zh) 2012-02-29
BRPI1007557A2 (pt) 2016-02-16
RU2011135958A (ru) 2013-03-10
EP2392354A1 (en) 2011-12-07
JPWO2010087447A1 (ja) 2012-08-02
AU2010208880A1 (en) 2011-08-18
EP2392354A4 (en) 2012-08-08
SG173158A1 (en) 2011-08-29
US20110294901A1 (en) 2011-12-01
KR20110117145A (ko) 2011-10-26

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Legal Events

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