MX2011004317A - Inhibidores del receptor-3 del factor de crecimiento del fibroblasto (rtf-3) y metodos de tratamiento. - Google Patents
Inhibidores del receptor-3 del factor de crecimiento del fibroblasto (rtf-3) y metodos de tratamiento.Info
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- MX2011004317A MX2011004317A MX2011004317A MX2011004317A MX2011004317A MX 2011004317 A MX2011004317 A MX 2011004317A MX 2011004317 A MX2011004317 A MX 2011004317A MX 2011004317 A MX2011004317 A MX 2011004317A MX 2011004317 A MX2011004317 A MX 2011004317A
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- antibody
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Chemical Kinetics & Catalysis (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US19685508P | 2008-10-20 | 2008-10-20 | |
| PCT/US2009/060840 WO2010048026A2 (en) | 2008-10-20 | 2009-10-15 | Fibroblast growth factor receptor-3 (fgfr-3) inhibitors and methods of treatment |
Publications (1)
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|---|---|
| MX2011004317A true MX2011004317A (es) | 2011-06-24 |
Family
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Family Applications (1)
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|---|---|---|---|
| MX2011004317A MX2011004317A (es) | 2008-10-20 | 2009-10-15 | Inhibidores del receptor-3 del factor de crecimiento del fibroblasto (rtf-3) y metodos de tratamiento. |
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| US (3) | US8043618B2 (show.php) |
| EP (1) | EP2342232A2 (show.php) |
| JP (1) | JP5577345B2 (show.php) |
| KR (1) | KR101370798B1 (show.php) |
| CN (2) | CN103524620A (show.php) |
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| BR (1) | BRPI0919832A8 (show.php) |
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| MX (1) | MX2011004317A (show.php) |
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| TW (1) | TWI381848B (show.php) |
| UA (1) | UA101681C2 (show.php) |
| WO (1) | WO2010048026A2 (show.php) |
| ZA (1) | ZA201101938B (show.php) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI381848B (zh) | 2008-10-20 | 2013-01-11 | Imclone Llc | 抗纖維母細胞生長因子受體-3 (fgfr-3) 抗體及包含其之醫藥組合物 |
| HRP20150965T1 (hr) | 2009-03-25 | 2015-11-06 | Genentech, Inc. | Anti-fgr3 protutijela i metode koje ih koriste |
| WO2013088191A1 (en) | 2011-12-12 | 2013-06-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Antagonist of the fibroblast growth factor receptor 3 (fgfr3) for use in the treatment or the prevention of skeletal disorders linked with abnormal activation of fgfr3 |
| KR20160002681A (ko) | 2013-01-16 | 2016-01-08 | 인썸(인스티튜트 내셔날 드 라 싼테 에 드 라 리셰르셰메디칼르) | 골격 성장 지연 질환의 예방 또는 치료에 사용하기 위한 용해성 섬유아세포 성장 인자 수용체 3(fgr3) 폴리펩티드 |
| JP2016510751A (ja) | 2013-03-06 | 2016-04-11 | ジェネンテック， インコーポレイテッド | 抗がん剤耐性を治療及び予防する方法 |
| TWI541022B (zh) | 2013-12-18 | 2016-07-11 | 應克隆公司 | 針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法 |
| US10519240B2 (en) | 2014-03-25 | 2019-12-31 | Regeneron Pharmaceuticals, Inc. | Anti-FGFR1c antibody-FGF21 fusion proteins |
| US20170101466A1 (en) * | 2014-06-03 | 2017-04-13 | Masahisa Handa | Anti-blys antibodies |
| CN107073121A (zh) | 2014-06-13 | 2017-08-18 | 基因泰克公司 | 治疗及预防癌症药物抗性的方法 |
| CN111896903A (zh) * | 2014-09-05 | 2020-11-06 | 海珀菲纳研究股份有限公司 | 噪声抑制方法和设备 |
| EA037920B1 (ru) | 2014-09-26 | 2021-06-07 | Янссен Фармацевтика Нв | Использование панелей мутантных генов fgfr для выявления онкологических пациентов, которые будут поддаваться лечению ингибитором fgfr |
| JP6774421B2 (ja) * | 2015-02-19 | 2020-10-21 | フュージョン ファーマシューティカルズ インク． | がんの治療のための方法、組成物、及びキット |
| WO2016139227A1 (en) | 2015-03-03 | 2016-09-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fgfr3 antagonists |
| TW201711702A (zh) | 2015-06-04 | 2017-04-01 | 應克隆公司 | 使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法 |
| MA43416A (fr) | 2015-12-11 | 2018-10-17 | Regeneron Pharma | Méthodes pour ralentir ou empêcher la croissance de tumeurs résistantes au blocage de l'egfr et/ou d'erbb3 |
| RU2751483C2 (ru) | 2016-07-07 | 2021-07-14 | Пфайзер Инк. | Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения |
| US20180244785A1 (en) * | 2017-01-09 | 2018-08-30 | Merrimack Pharmaceuticals, Inc. | Anti-fgfr antibodies and methods of use |
| AU2021327387A1 (en) | 2020-08-21 | 2023-05-04 | Genzyme Corporation | Fgfr3 antibodies and methods of use |
| CN114015770B (zh) * | 2021-12-30 | 2022-04-26 | 佛山市第三人民医院(佛山市精神卫生中心) | 精神分裂全外周血rna标志物fgfr3及其应用 |
| KR20250116795A (ko) * | 2022-11-14 | 2025-08-01 | 리제너론 파마슈티칼스 인코포레이티드 | 별아교세포로의 섬유아세포 성장 인자 수용체 3-매개된 전달을 위한 조성물 및 방법 |
| IL322053A (en) | 2023-01-13 | 2025-09-01 | Regeneron Pharma | FGFR3 binding molecules and methods of using them |
| WO2025240335A1 (en) | 2024-05-13 | 2025-11-20 | Regeneron Pharmaceuticals, Inc. | Fgfr3 binding molecules and methods of use thereof |
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| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| ATE120761T1 (de) | 1987-05-21 | 1995-04-15 | Creative Biomolecules Inc | Multifunktionelle proteine mit vorbestimmter zielsetzung. |
| WO2002102973A2 (en) * | 2001-06-20 | 2002-12-27 | Prochon Biotech Ltd. | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
| US20070248605A1 (en) | 2003-12-19 | 2007-10-25 | Five Prime Therapetutics, Inc. | Fibroblast Growth Factor Receptors 1,2,3, and 4 as Targets for Therapeutic Intervention |
| CN101460518B (zh) * | 2006-06-06 | 2012-08-22 | 克鲁塞尔荷兰公司 | 针对肠球菌和金黄色葡萄球菌具有杀伤活性的人结合分子及其应用 |
| CA2663388C (en) * | 2006-09-07 | 2017-01-17 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| EP2185719B1 (en) * | 2007-08-02 | 2013-11-13 | NovImmune SA | Anti-rantes antibodies and methods of use thereof |
| KR102057826B1 (ko) * | 2008-04-11 | 2019-12-20 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복 결합하는 항원 결합 분자 |
| US8187601B2 (en) * | 2008-07-01 | 2012-05-29 | Aveo Pharmaceuticals, Inc. | Fibroblast growth factor receptor 3 (FGFR3) binding proteins |
| TWI381848B (zh) * | 2008-10-20 | 2013-01-11 | Imclone Llc | 抗纖維母細胞生長因子受體-3 (fgfr-3) 抗體及包含其之醫藥組合物 |
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| CN102186884A (zh) | 2011-09-14 |
| UA101681C2 (ru) | 2013-04-25 |
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| TW201026325A (en) | 2010-07-16 |
| KR20110056554A (ko) | 2011-05-30 |
| AU2009307841A1 (en) | 2010-04-29 |
| BRPI0919832A8 (pt) | 2019-01-08 |
| EA201170590A1 (ru) | 2011-10-31 |
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| KR101370798B1 (ko) | 2014-03-14 |
| EA021584B1 (ru) | 2015-07-30 |
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| AR073770A1 (es) | 2010-12-01 |
| CN103524620A (zh) | 2014-01-22 |
| CA2741127A1 (en) | 2010-04-29 |
| JP5577345B2 (ja) | 2014-08-20 |
| JP2012505912A (ja) | 2012-03-08 |
| CA2741127C (en) | 2015-06-02 |
| US8182815B2 (en) | 2012-05-22 |
| US20100098696A1 (en) | 2010-04-22 |
| AU2009307841B2 (en) | 2013-09-12 |
| TWI381848B (zh) | 2013-01-11 |
| IL211807A0 (en) | 2011-06-30 |
| US8043618B2 (en) | 2011-10-25 |
| WO2010048026A2 (en) | 2010-04-29 |
| NZ592369A (en) | 2013-02-22 |
| WO2010048026A3 (en) | 2010-07-15 |
| CN102186884B (zh) | 2014-08-13 |
| BRPI0919832A2 (pt) | 2015-12-15 |
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