MX2011000455A - Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos. - Google Patents

Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos.

Info

Publication number
MX2011000455A
MX2011000455A MX2011000455A MX2011000455A MX2011000455A MX 2011000455 A MX2011000455 A MX 2011000455A MX 2011000455 A MX2011000455 A MX 2011000455A MX 2011000455 A MX2011000455 A MX 2011000455A MX 2011000455 A MX2011000455 A MX 2011000455A
Authority
MX
Mexico
Prior art keywords
mab
gal
fgfr2
humanized
human
Prior art date
Application number
MX2011000455A
Other languages
English (en)
Spanish (es)
Inventor
Kyung Jin Kim
Hangil Park
Maximiliano Vasquez
Wei-Meng Zhao
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of MX2011000455A publication Critical patent/MX2011000455A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • G01N33/5759
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2011000455A 2008-11-07 2009-11-06 Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos. MX2011000455A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11268608P 2008-11-07 2008-11-07
US16487009P 2009-03-30 2009-03-30
PCT/US2009/063647 WO2010054265A2 (en) 2008-11-07 2009-11-06 Monoclonal antibodies to fibroblast growth factor receptor 2

Publications (1)

Publication Number Publication Date
MX2011000455A true MX2011000455A (es) 2011-02-25

Family

ID=42153600

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011000455A MX2011000455A (es) 2008-11-07 2009-11-06 Anticuerpos monoclonales especificos al receptor 2 del factor de crecimiento de fibroblastos.

Country Status (20)

Country Link
US (8) US8101723B2 (enExample)
EP (4) EP2365828B1 (enExample)
JP (8) JP5627591B2 (enExample)
KR (1) KR101699432B1 (enExample)
CN (1) CN102131524B (enExample)
AU (1) AU2009313357B2 (enExample)
BR (1) BRPI0917315B8 (enExample)
CA (1) CA2733668C (enExample)
DK (3) DK2842573T3 (enExample)
ES (3) ES2523740T3 (enExample)
HR (2) HRP20171640T1 (enExample)
HU (1) HUE035700T2 (enExample)
LT (2) LT2842573T (enExample)
MX (1) MX2011000455A (enExample)
NO (1) NO2842573T3 (enExample)
PL (3) PL2842573T3 (enExample)
PT (3) PT2365828E (enExample)
RU (1) RU2546254C9 (enExample)
SI (2) SI3290052T1 (enExample)
WO (1) WO2010054265A2 (enExample)

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EP3290052A1 (en) 2018-03-07
HK1249053A1 (en) 2018-10-26
ES2770134T3 (es) 2020-06-30
KR101699432B1 (ko) 2017-01-24
ES2646168T3 (es) 2017-12-12
US10689448B2 (en) 2020-06-23
US10138301B2 (en) 2018-11-27
US8603987B2 (en) 2013-12-10
RU2546254C9 (ru) 2015-07-10
JP2014240385A (ja) 2014-12-25
CA2733668C (en) 2022-08-30
US20190153105A1 (en) 2019-05-23
CA3166399A1 (en) 2010-05-14
EP2842573B1 (en) 2017-09-27
US20160362496A1 (en) 2016-12-15
HK1207974A1 (en) 2016-02-19
WO2010054265A2 (en) 2010-05-14
AU2009313357A1 (en) 2010-05-14
JP2023116746A (ja) 2023-08-22
PT2842573T (pt) 2017-12-04
RU2011141890A (ru) 2013-04-27
US20140193899A1 (en) 2014-07-10
JP2019052165A (ja) 2019-04-04
BRPI0917315B1 (pt) 2020-12-08
JP6661734B2 (ja) 2020-03-11
EP2365828A2 (en) 2011-09-21
US20180094063A1 (en) 2018-04-05
HRP20171640T1 (hr) 2018-01-12
NO2842573T3 (enExample) 2018-02-24
JP6960485B2 (ja) 2021-11-05
LT2842573T (lt) 2017-12-11
DK3290052T3 (da) 2020-02-03
US9382324B2 (en) 2016-07-05
EP2842573A1 (en) 2015-03-04
WO2010054265A3 (en) 2010-09-16
JP6342223B2 (ja) 2018-06-13
PL3290052T3 (pl) 2020-06-29
DK2842573T3 (en) 2017-10-30
KR20110081141A (ko) 2011-07-13
BRPI0917315B8 (pt) 2021-05-25
PT3290052T (pt) 2020-02-06
US20120134994A1 (en) 2012-05-31
EP2365828B1 (en) 2014-10-15
SI2842573T1 (en) 2018-01-31
JP2012508184A (ja) 2012-04-05
EP2365828A4 (en) 2012-06-06
JP7301106B2 (ja) 2023-06-30
JP2020096615A (ja) 2020-06-25
AU2009313357B2 (en) 2015-06-11
ES2523740T3 (es) 2014-12-01
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