MX2010011176A - Inmunoanalisis sensible que utiliza nanoparticulas revestidas. - Google Patents
Inmunoanalisis sensible que utiliza nanoparticulas revestidas.Info
- Publication number
- MX2010011176A MX2010011176A MX2010011176A MX2010011176A MX2010011176A MX 2010011176 A MX2010011176 A MX 2010011176A MX 2010011176 A MX2010011176 A MX 2010011176A MX 2010011176 A MX2010011176 A MX 2010011176A MX 2010011176 A MX2010011176 A MX 2010011176A
- Authority
- MX
- Mexico
- Prior art keywords
- analyte
- reagent
- labeled
- sample
- detection
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title claims abstract description 97
- 238000003018 immunoassay Methods 0.000 title abstract description 12
- 238000012360 testing method Methods 0.000 claims abstract description 80
- 239000003153 chemical reaction reagent Substances 0.000 claims description 139
- 239000007788 liquid Substances 0.000 claims description 104
- 239000012491 analyte Substances 0.000 claims description 102
- 238000001514 detection method Methods 0.000 claims description 99
- 238000000034 method Methods 0.000 claims description 73
- 239000012528 membrane Substances 0.000 claims description 42
- 239000002245 particle Substances 0.000 claims description 40
- 239000003446 ligand Substances 0.000 claims description 37
- 238000001069 Raman spectroscopy Methods 0.000 claims description 27
- 238000009739 binding Methods 0.000 claims description 21
- 230000027455 binding Effects 0.000 claims description 20
- 238000004891 communication Methods 0.000 claims description 17
- 239000012530 fluid Substances 0.000 claims description 15
- 238000002372 labelling Methods 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 12
- 239000002250 absorbent Substances 0.000 claims description 11
- 230000002745 absorbent Effects 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 9
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 241000700605 Viruses Species 0.000 claims description 7
- 102000039446 nucleic acids Human genes 0.000 claims description 7
- 108020004707 nucleic acids Proteins 0.000 claims description 7
- 150000007523 nucleic acids Chemical class 0.000 claims description 7
- 238000004458 analytical method Methods 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 238000013102 re-test Methods 0.000 claims description 6
- 230000004044 response Effects 0.000 claims description 5
- 239000002207 metabolite Substances 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- 150000003384 small molecules Chemical class 0.000 claims description 3
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims description 2
- 229910052744 lithium Inorganic materials 0.000 claims description 2
- 238000005259 measurement Methods 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 241001139947 Mida Species 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000011258 core-shell material Substances 0.000 claims 1
- 239000000523 sample Substances 0.000 description 58
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 43
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 29
- 239000010931 gold Substances 0.000 description 24
- 229910052737 gold Inorganic materials 0.000 description 24
- 239000000377 silicon dioxide Substances 0.000 description 21
- 230000035945 sensitivity Effects 0.000 description 19
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 description 15
- 208000037797 influenza A Diseases 0.000 description 13
- 238000003556 assay Methods 0.000 description 12
- 239000000084 colloidal system Substances 0.000 description 11
- 238000002474 experimental method Methods 0.000 description 10
- 239000011521 glass Substances 0.000 description 10
- 239000000243 solution Substances 0.000 description 10
- 125000003396 thiol group Chemical group [H]S* 0.000 description 10
- 239000000020 Nitrocellulose Substances 0.000 description 7
- 229920001220 nitrocellulos Polymers 0.000 description 7
- 230000009471 action Effects 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 241000712431 Influenza A virus Species 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 238000012125 lateral flow test Methods 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000011230 binding agent Substances 0.000 description 4
- 229920002678 cellulose Polymers 0.000 description 4
- 239000001913 cellulose Substances 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 206010022000 influenza Diseases 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- MWVTWFVJZLCBMC-UHFFFAOYSA-N 4,4'-bipyridine Chemical group C1=NC=CC(C=2C=CN=CC=2)=C1 MWVTWFVJZLCBMC-UHFFFAOYSA-N 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 3
- 230000004308 accommodation Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 239000008393 encapsulating agent Substances 0.000 description 3
- 238000011068 loading method Methods 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000712461 unidentified influenza virus Species 0.000 description 3
- 239000004677 Nylon Substances 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000003638 chemical reducing agent Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000003989 dielectric material Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 238000005206 flow analysis Methods 0.000 description 2
- 208000037798 influenza B Diseases 0.000 description 2
- 239000002923 metal particle Substances 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- QTQPVLDZQVPLGV-UHFFFAOYSA-N oxomemazine Chemical compound C1=CC=C2N(CC(CN(C)C)C)C3=CC=CC=C3S(=O)(=O)C2=C1 QTQPVLDZQVPLGV-UHFFFAOYSA-N 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000002310 reflectometry Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 238000010561 standard procedure Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 239000011534 wash buffer Substances 0.000 description 2
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 description 1
- 241000606161 Chlamydia Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 238000005773 Enders reaction Methods 0.000 description 1
- 208000009889 Herpes Simplex Diseases 0.000 description 1
- 241000713196 Influenza B virus Species 0.000 description 1
- 241000701076 Macacine alphaherpesvirus 1 Species 0.000 description 1
- PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 description 1
- 238000001237 Raman spectrum Methods 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- 241000698291 Rugosa Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 240000007313 Tilia cordata Species 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000001246 colloidal dispersion Methods 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 230000009137 competitive binding Effects 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- -1 mercaptopropyl Chemical group 0.000 description 1
- 229910052976 metal sulfide Inorganic materials 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000009149 molecular binding Effects 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 239000013110 organic ligand Substances 0.000 description 1
- 239000000123 paper Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 235000013446 pixi Nutrition 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 239000002964 rayon Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000006722 reduction reaction Methods 0.000 description 1
- VUFNRPJNRFOTGK-UHFFFAOYSA-M sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate Chemical compound [Na+].O=C1C(S(=O)(=O)[O-])CC(=O)N1OC(=O)C1CCC(CN2C(C=CC2=O)=O)CC1 VUFNRPJNRFOTGK-UHFFFAOYSA-M 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- PSGGLQPNTOVNKU-UHFFFAOYSA-N tetrakis(pyridine)silver(ii) peroxydisulfate Chemical compound [Ag].C1=CC=NC=C1.C1=CC=NC=C1.C1=CC=NC=C1.C1=CC=NC=C1 PSGGLQPNTOVNKU-UHFFFAOYSA-N 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- YUYCVXFAYWRXLS-UHFFFAOYSA-N trimethoxysilane Chemical compound CO[SiH](OC)OC YUYCVXFAYWRXLS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54391—Immunochromatographic test strips based on vertical flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7103508P | 2008-04-09 | 2008-04-09 | |
| PCT/US2009/039951 WO2009126735A1 (en) | 2008-04-09 | 2009-04-08 | Sensitive immunoassays using coated nanoparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010011176A true MX2010011176A (es) | 2011-02-24 |
Family
ID=40756968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010011176A MX2010011176A (es) | 2008-04-09 | 2009-04-08 | Inmunoanalisis sensible que utiliza nanoparticulas revestidas. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20090305231A1 (enExample) |
| EP (2) | EP2271939B1 (enExample) |
| JP (3) | JP5792614B2 (enExample) |
| CN (2) | CN102016585B (enExample) |
| AU (1) | AU2009233755B2 (enExample) |
| BR (1) | BRPI0911067B8 (enExample) |
| CA (1) | CA2721064C (enExample) |
| ES (2) | ES2627190T3 (enExample) |
| MX (1) | MX2010011176A (enExample) |
| TW (1) | TW200946913A (enExample) |
| WO (1) | WO2009126735A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291508A1 (en) * | 2008-05-20 | 2009-11-26 | Rapid Pathogen Screening Inc. | Nanoparticles in diagnostic tests |
| US8470608B2 (en) * | 2008-05-20 | 2013-06-25 | Rapid Pathogen Screening, Inc | Combined visual/fluorescence analyte detection test |
| US8669052B2 (en) | 2008-06-10 | 2014-03-11 | Rapid Pathogen Screening, Inc. | Lateral flow nucleic acid detector |
| US8609433B2 (en) | 2009-12-04 | 2013-12-17 | Rapid Pathogen Screening, Inc. | Multiplanar lateral flow assay with sample compressor |
| US8962260B2 (en) | 2008-05-20 | 2015-02-24 | Rapid Pathogen Screening, Inc. | Method and device for combined detection of viral and bacterial infections |
| US9068981B2 (en) | 2009-12-04 | 2015-06-30 | Rapid Pathogen Screening, Inc. | Lateral flow assays with time delayed components |
| US20130196310A1 (en) | 2008-05-20 | 2013-08-01 | Rapid Pathogen Screening, Inc. | Method and Device for Combined Detection of Viral and Bacterial Infections |
| US8815609B2 (en) | 2008-05-20 | 2014-08-26 | Rapid Pathogen Screening, Inc. | Multiplanar lateral flow assay with diverting zone |
| US20110086359A1 (en) | 2008-06-10 | 2011-04-14 | Rapid Pathogen Screening, Inc. | Lateral flow assays |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) * | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| WO2012051218A2 (en) * | 2010-10-11 | 2012-04-19 | Mbio Diagnostics, Inc. | Fluidic assay cartridge with controlled passive flow |
| US10114020B2 (en) | 2010-10-11 | 2018-10-30 | Mbio Diagnostics, Inc. | System and device for analyzing a fluidic sample |
| CA2778561C (en) * | 2011-05-31 | 2020-10-13 | Ghandi, Khashayar | Magnetic nanocomposite material and processes for the production thereof |
| US9715579B2 (en) | 2011-09-09 | 2017-07-25 | Alverix, Inc. | Distributed network of in-vitro diagnostic devices |
| US9524372B2 (en) | 2011-09-09 | 2016-12-20 | Alverix, Inc. | In-vitro diagnostic device using external information in conjunction with test results |
| US10725033B2 (en) * | 2012-01-31 | 2020-07-28 | Regents Of The University Of Minnesota | Lateral flow assays with thermal contrast readers |
| US10816492B2 (en) * | 2012-01-31 | 2020-10-27 | Regents Of The University Of Minnesota | Lateral flow assays with thermal contrast readers |
| EP2884264B1 (en) | 2012-08-10 | 2019-11-20 | Hamamatsu Photonics K.K. | Surface-enhanced raman scattering element, and method for producing same |
| CN104508466B (zh) | 2012-08-10 | 2018-07-17 | 浜松光子学株式会社 | 表面增强拉曼散射元件 |
| JP6151948B2 (ja) * | 2013-03-29 | 2017-06-21 | 浜松ホトニクス株式会社 | 表面増強ラマン散乱ユニット及びラマン分光分析方法 |
| EP2911791A4 (en) | 2012-10-29 | 2016-11-02 | Mbio Diagnostics Inc | BIOPARTICLE IDENTIFICATION SYSTEM, CARTRIDGE AND RELATED METHODS |
| EP2811301B1 (en) | 2012-11-15 | 2017-05-10 | Ortho-Clinical Diagnostics, Inc. | Quality/process control of a lateral flow assay device based on flow monitoring |
| KR102298172B1 (ko) | 2013-09-06 | 2021-09-06 | 아카데미아 시니카 | 변화된 글리코실 그룹을 갖는 당지질을 사용한 인간 iNKT 세포 활성화 |
| US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
| KR20240096599A (ko) | 2014-05-27 | 2024-06-26 | 아카데미아 시니카 | 항-cd20 글리코항체 및 이의 용도 |
| AU2015267052A1 (en) | 2014-05-27 | 2016-12-15 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| JP7063538B2 (ja) | 2014-05-28 | 2022-05-09 | アカデミア シニカ | 抗TNFα糖操作抗体群およびその使用 |
| WO2016072806A2 (ko) | 2014-11-06 | 2016-05-12 | 포항공과대학교 산학협력단 | 코어-쉘 구조의 페로브스카이트 나노결정입자 발광체, 이의 제조방법 및 이를 이용한 발광소자 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| US10808287B2 (en) | 2015-10-23 | 2020-10-20 | Rapid Pathogen Screening, Inc. | Methods and devices for accurate diagnosis of infections |
| CA3024569A1 (en) | 2016-06-22 | 2017-12-28 | Becton, Dickinson And Company | Modular assay reader device |
| AU2017316663B2 (en) | 2016-08-22 | 2024-02-22 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
| US10796901B2 (en) * | 2016-09-29 | 2020-10-06 | Nanoco Technologies Ltd. | Shelling of halide perovskite nanoparticles for the prevention of anion exchange |
| CN110554018A (zh) * | 2018-05-31 | 2019-12-10 | 上海市刑事科学技术研究院 | 检测水溶液中4-溴甲卡西酮的表面增强拉曼材料及其制备方法 |
| CN111686826B (zh) * | 2019-03-15 | 2023-05-23 | 国家纳米科学中心 | 分层结构的微流控芯片及其应用 |
| JP7607312B2 (ja) * | 2020-01-09 | 2024-12-27 | 国立大学法人山梨大学 | 標識化シリカコート金ナノロッド及びその製造方法 |
| WO2021252810A1 (en) | 2020-06-10 | 2021-12-16 | Checkable Medical Incorporated | In vitro diagnostic device |
| TWI756764B (zh) * | 2020-07-31 | 2022-03-01 | 國立中興大學 | 光電流電極及光電免疫感測裝置 |
| WO2022179647A1 (en) * | 2021-02-24 | 2022-09-01 | Univerzita Palackeho V Olomouci | Test strip for surface-enhanced raman spectroscopy, method for its preparation and use thereof |
| US20220317124A1 (en) | 2021-04-01 | 2022-10-06 | Becton Dickinson And Company | Methods for enhancing specificity and sensitivity of group a streptococcus immunoassay |
| TWI792554B (zh) * | 2021-09-10 | 2023-02-11 | 財團法人工業技術研究院 | 鈣鈦礦前驅物溶液檢測法 |
| WO2023055305A1 (en) * | 2021-09-28 | 2023-04-06 | National Science And Technology Development Agency | Qualitative dextran detection device and use thereof |
| CN114720450A (zh) * | 2022-03-29 | 2022-07-08 | 中国工程物理研究院激光聚变研究中心 | 一种新冠病毒拉曼标记型抗原检测试纸条及其制备方法 |
| CN115792216B (zh) * | 2022-11-25 | 2023-11-03 | 中国农业科学院北京畜牧兽医研究所 | 用于检测毒素的侧向层析试纸条、制备方法和使用方法 |
| CN116338169A (zh) * | 2022-12-26 | 2023-06-27 | 北京科技大学 | 以微球反射镜作为探针的显微分析方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4920046A (en) * | 1987-02-20 | 1990-04-24 | Becton, Dickinson And Company | Process, test device, and test kit for a rapid assay having a visible readout |
| CA1303983C (en) * | 1987-03-27 | 1992-06-23 | Robert W. Rosenstein | Solid phase assay |
| USRE38430E1 (en) * | 1987-03-27 | 2004-02-17 | Becton, Dickinson And Company | Solid phase chromatographic immunoassay |
| ES2150428T3 (es) * | 1987-04-27 | 2000-12-01 | Unilever Nv | Ensayos de union especifica. |
| CA1313616C (en) * | 1987-06-01 | 1993-02-16 | Robert B. Sargeant | Lateral flow, non-bibulous membrane protocols |
| AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
| US6818199B1 (en) * | 1994-07-29 | 2004-11-16 | James F. Hainfeld | Media and methods for enhanced medical imaging |
| US6194220B1 (en) | 1996-09-25 | 2001-02-27 | Becton, Dickinson And Company | Non-instrumented assay with quantitative and qualitative results |
| US5998221A (en) | 1996-09-25 | 1999-12-07 | Becton, Dickinson And Company | Non-instrumented assay with quantitative and qualitative results |
| US5798273A (en) * | 1996-09-25 | 1998-08-25 | Becton Dickinson And Company | Direct read lateral flow assay for small analytes |
| JP2001502052A (ja) * | 1996-09-25 | 2001-02-13 | ユニバーサル ヘルスウォッチ,インコーポレーテッド | 液体移動および干渉に対する抵抗を改良した診断用検査デバイス |
| EP1062510A2 (en) * | 1998-03-10 | 2000-12-27 | Strategic Diagnostics Inc. | Integrated assay device and methods of production and use |
| US6136610A (en) * | 1998-11-23 | 2000-10-24 | Praxsys Biosystems, Inc. | Method and apparatus for performing a lateral flow assay |
| WO2000031538A1 (en) * | 1998-11-23 | 2000-06-02 | Praxsys Biosystems, Inc. | Improved lateral flow assays |
| WO2001018235A2 (en) * | 1999-09-09 | 2001-03-15 | Eichrom Technologies, Inc. | Lateral flow device with metal oxide indicator and assay method employing same |
| ES2296648T3 (es) | 1999-10-06 | 2008-05-01 | Oxonica Inc. | Nanoparticulas compuestas espectroscopicamente activas superficialmente potenciadas. |
| US7052831B2 (en) * | 2000-09-29 | 2006-05-30 | Becton Dickinson And Company | Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device |
| ATE421570T1 (de) * | 2002-06-07 | 2009-02-15 | Cholestech Corp | Automatisierte kassette für eine vorrichtung zur durchführung von immunoanalytischen tests und verfahren zu ihrer verwendung |
| WO2004081568A1 (ja) * | 2003-03-10 | 2004-09-23 | Daiichi Pure Chemicals Co. Ltd. | 検体の検査方法及びその検査方法に用いる検体収容用容器 |
| US7659107B2 (en) * | 2003-09-23 | 2010-02-09 | Epinex Diagnostics, Inc. | Rapid test for glycated albumin |
| US20050148100A1 (en) * | 2003-12-30 | 2005-07-07 | Intel Corporation | Methods and devices for using Raman-active probe constructs to assay biological samples |
| JP2006071520A (ja) * | 2004-09-03 | 2006-03-16 | Enbiotec Laboratories:Kk | Pcbの簡易検出方法 |
| US7723100B2 (en) | 2006-01-13 | 2010-05-25 | Becton, Dickinson And Company | Polymer coated SERS nanotag |
| WO2007090058A2 (en) * | 2006-01-27 | 2007-08-09 | Oxonica, Inc. | Lateral flow immunoassay with encapsulated detection modality |
-
2009
- 2009-04-08 JP JP2011504156A patent/JP5792614B2/ja active Active
- 2009-04-08 EP EP09730869.6A patent/EP2271939B1/en active Active
- 2009-04-08 WO PCT/US2009/039951 patent/WO2009126735A1/en not_active Ceased
- 2009-04-08 ES ES15172303.8T patent/ES2627190T3/es active Active
- 2009-04-08 BR BRPI0911067A patent/BRPI0911067B8/pt active IP Right Grant
- 2009-04-08 ES ES09730869.6T patent/ES2544257T3/es active Active
- 2009-04-08 AU AU2009233755A patent/AU2009233755B2/en active Active
- 2009-04-08 CN CN200980116000.5A patent/CN102016585B/zh active Active
- 2009-04-08 CA CA2721064A patent/CA2721064C/en active Active
- 2009-04-08 MX MX2010011176A patent/MX2010011176A/es active IP Right Grant
- 2009-04-08 EP EP15172303.8A patent/EP2952897B1/en active Active
- 2009-04-08 US US12/420,574 patent/US20090305231A1/en not_active Abandoned
- 2009-04-08 CN CN201710803380.6A patent/CN107561270B/zh active Active
- 2009-04-09 TW TW098111807A patent/TW200946913A/zh unknown
-
2012
- 2012-10-25 US US13/659,977 patent/US20130281310A1/en not_active Abandoned
-
2015
- 2015-04-24 JP JP2015089316A patent/JP2015148629A/ja active Pending
-
2016
- 2016-09-23 JP JP2016186126A patent/JP6379149B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107561270B (zh) | 2019-06-04 |
| JP2011516889A (ja) | 2011-05-26 |
| JP2015148629A (ja) | 2015-08-20 |
| CN102016585A (zh) | 2011-04-13 |
| CN107561270A (zh) | 2018-01-09 |
| US20090305231A1 (en) | 2009-12-10 |
| BRPI0911067A2 (pt) | 2015-12-29 |
| CA2721064A1 (en) | 2009-10-15 |
| JP5792614B2 (ja) | 2015-10-14 |
| JP6379149B2 (ja) | 2018-08-22 |
| ES2544257T3 (es) | 2015-08-28 |
| BRPI0911067B1 (pt) | 2020-10-20 |
| EP2271939B1 (en) | 2015-06-17 |
| EP2952897A1 (en) | 2015-12-09 |
| AU2009233755A1 (en) | 2009-10-15 |
| WO2009126735A1 (en) | 2009-10-15 |
| CN102016585B (zh) | 2017-10-10 |
| EP2952897B1 (en) | 2017-03-22 |
| US20130281310A1 (en) | 2013-10-24 |
| JP2017015732A (ja) | 2017-01-19 |
| AU2009233755B2 (en) | 2015-11-26 |
| ES2627190T3 (es) | 2017-07-27 |
| CA2721064C (en) | 2016-11-01 |
| BRPI0911067B8 (pt) | 2021-07-27 |
| TW200946913A (en) | 2009-11-16 |
| EP2271939A1 (en) | 2011-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2010011176A (es) | Inmunoanalisis sensible que utiliza nanoparticulas revestidas. | |
| US12306181B2 (en) | Self-referencing sensor for chemical detection | |
| Bedford et al. | Surface plasmon resonance biosensors incorporating gold nanoparticles | |
| CA2846909C (en) | Method and apparatus for lspr chemical detection using a sensor comprising a porous membrane and nanoparticles | |
| JP2003504642A (ja) | 生体感知用途のための金属微細シェル | |
| JP2009530598A (ja) | 化学的検知装置 | |
| TWI486571B (zh) | 感測方法 | |
| JP2008157923A (ja) | 化学センシング装置及び化学センシング方法 | |
| Wang et al. | Sensitivity investigation of a biosensor with resonant coupling of propagating surface plasmons to localized surface plasmons in the near infrared region | |
| US20110195516A1 (en) | Wire grid substrate structure and method for manufacturing such a substrate | |
| Mitchell et al. | Surface plasmon resonance biosensors for highly sensitive detection of small biomolecules | |
| US20130052632A1 (en) | Method for sensing a chemical | |
| JP7756407B1 (ja) | イムノアッセイ方法及びイムノアッセイ装置 | |
| EP4298429B1 (en) | Test strip for surface-enhanced raman spectroscopy, method of preparation and use thereof | |
| Amissah | Optimization of a Sers-Based Vertical Flow Immunoassay Utilizing a Plasmonic Syringe Filter for Rapid Biomarker Detection and Quantification | |
| Filippone | Preparation and Characterization of Paper-Based and Nanoparticle-Enhanced SERS Substrates for Biosensor Applications |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |