MX2010004332A - Esteres de camptotecina cristalinos hidratados para el tratamiento de cancer. - Google Patents
Esteres de camptotecina cristalinos hidratados para el tratamiento de cancer.Info
- Publication number
- MX2010004332A MX2010004332A MX2010004332A MX2010004332A MX2010004332A MX 2010004332 A MX2010004332 A MX 2010004332A MX 2010004332 A MX2010004332 A MX 2010004332A MX 2010004332 A MX2010004332 A MX 2010004332A MX 2010004332 A MX2010004332 A MX 2010004332A
- Authority
- MX
- Mexico
- Prior art keywords
- camptothecin
- cancer
- treatment
- hydrated crystalline
- crystalline
- Prior art date
Links
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 title abstract 4
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title abstract 4
- 229940127093 camptothecin Drugs 0.000 title abstract 4
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title 1
- -1 aliphatic ester hydrates Chemical class 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/923,727 US7572803B2 (en) | 2007-10-25 | 2007-10-25 | Hydrated crystalline esters of camptothecin |
| PCT/US2008/081047 WO2009055633A1 (en) | 2007-10-25 | 2008-10-24 | Hydrated crystalline esters of camptothecin for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010004332A true MX2010004332A (es) | 2010-05-20 |
Family
ID=40229972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010004332A MX2010004332A (es) | 2007-10-25 | 2008-10-24 | Esteres de camptotecina cristalinos hidratados para el tratamiento de cancer. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7572803B2 (enExample) |
| EP (1) | EP2205605B1 (enExample) |
| JP (1) | JP5487111B2 (enExample) |
| KR (1) | KR20100082358A (enExample) |
| CN (1) | CN101730701B (enExample) |
| BR (1) | BRPI0816584A2 (enExample) |
| CA (1) | CA2703054C (enExample) |
| ES (1) | ES2396222T3 (enExample) |
| MX (1) | MX2010004332A (enExample) |
| RU (1) | RU2483071C2 (enExample) |
| WO (1) | WO2009055633A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130121921A1 (en) | 2011-11-11 | 2013-05-16 | The Christus Stehlin Foundation For Cancer Research | Rodent Therapeutic Model And Methods |
| US9387257B2 (en) * | 2014-01-17 | 2016-07-12 | Academia Sinica | Lung cancer specific peptides for targeted drug delivery and molecular imaging |
| US9675609B2 (en) * | 2015-11-11 | 2017-06-13 | Cao Pharmaceuticals Inc. | Nano- and micro-sized particles of 20-camptothecin or derivative thereof and pharmaceutical compositions containing same, and treatment of cancers therewith |
| US20220395497A1 (en) * | 2019-11-20 | 2022-12-15 | Vivacitas Oncology, Inc. | Cancer Treatment Using Camptothecin Derivatives |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552154A (en) | 1989-11-06 | 1996-09-03 | The Stehlin Foundation For Cancer Research | Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof |
| US6080751A (en) | 1992-01-14 | 2000-06-27 | The Stehlin Foundation For Cancer Research | Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof |
| US5352789A (en) | 1993-02-25 | 1994-10-04 | The Stehlin Foundation For Cancer Research | Methods for purifying camptothecin compounds |
| US5527913A (en) | 1993-02-25 | 1996-06-18 | The Stehlin Foundation For Cancer Research | Methods for purifying camptothecin compounds |
| US6407118B1 (en) | 1996-01-30 | 2002-06-18 | The Stehlin Foundation For Cancer Research | Derivatives of camptothecin and methods of treating cancer using these derivatives |
| US5731316A (en) | 1996-01-30 | 1998-03-24 | The Stehlin Foundation For Cancer Research | Derivatives of camptothecin and methods of treating cancer using these derivatives |
| US6096336A (en) | 1996-01-30 | 2000-08-01 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US5922877A (en) | 1997-08-05 | 1999-07-13 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
| USRE38408E1 (en) | 1997-08-05 | 2004-01-27 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
| US6228855B1 (en) | 1999-08-03 | 2001-05-08 | The Stehlin Foundation For Cancer Research | Aromatic esters of camptothecins and methods to treat cancers |
| US6352996B1 (en) | 1999-08-03 | 2002-03-05 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US6699875B2 (en) | 2002-05-06 | 2004-03-02 | The Stehlin Foundation For Cancer Research | Cascade esters of camptothecins and methods of treating cancer using these compounds |
| US6703399B2 (en) | 2002-05-06 | 2004-03-09 | The Stehlin Foundation For Cancer Research | Halo-alkyl esters of camptothecins and methods of treating cancer using these compounds |
| AU2004215560B2 (en) * | 2003-02-25 | 2009-09-24 | Kabushiki Kaisha Yakult Honsha | Method for preparing polymorphism of irinotecan hydrochloride |
| AR046579A1 (es) * | 2003-11-12 | 2005-12-14 | Smithkline Beecham Corp | Compuesto cristalino de topotecan, composicion farmaceutica que lo comprende, procedimiento para prepararlo y su uso para preparar dicha composicion farmaceutica |
| AU2006292328B2 (en) * | 2005-09-20 | 2012-12-20 | Scinopharm Singapore Pte, Ltd. | Novel crystal forms of irinotecan hydrochloride |
-
2007
- 2007-10-25 US US11/923,727 patent/US7572803B2/en active Active
-
2008
- 2008-10-24 KR KR1020107011223A patent/KR20100082358A/ko not_active Ceased
- 2008-10-24 EP EP08841603A patent/EP2205605B1/en not_active Not-in-force
- 2008-10-24 CA CA2703054A patent/CA2703054C/en active Active
- 2008-10-24 ES ES08841603T patent/ES2396222T3/es active Active
- 2008-10-24 CN CN200880013536XA patent/CN101730701B/zh not_active Expired - Fee Related
- 2008-10-24 WO PCT/US2008/081047 patent/WO2009055633A1/en not_active Ceased
- 2008-10-24 BR BRPI0816584-0A2A patent/BRPI0816584A2/pt not_active IP Right Cessation
- 2008-10-24 JP JP2010531264A patent/JP5487111B2/ja not_active Expired - Fee Related
- 2008-10-24 MX MX2010004332A patent/MX2010004332A/es active IP Right Grant
- 2008-10-24 RU RU2010120810/04A patent/RU2483071C2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2396222T3 (es) | 2013-02-20 |
| CN101730701A (zh) | 2010-06-09 |
| JP5487111B2 (ja) | 2014-05-07 |
| WO2009055633A1 (en) | 2009-04-30 |
| CA2703054C (en) | 2017-08-22 |
| RU2483071C2 (ru) | 2013-05-27 |
| RU2010120810A (ru) | 2011-11-27 |
| KR20100082358A (ko) | 2010-07-16 |
| JP2011500841A (ja) | 2011-01-06 |
| CA2703054A1 (en) | 2009-04-30 |
| EP2205605A1 (en) | 2010-07-14 |
| US20090111845A1 (en) | 2009-04-30 |
| CN101730701B (zh) | 2013-05-29 |
| BRPI0816584A2 (pt) | 2015-03-03 |
| US7572803B2 (en) | 2009-08-11 |
| EP2205605B1 (en) | 2012-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |