KR20100082358A - 암 치료를 위한 캄프토테신의 수화된 결정질 에스테르 - Google Patents
암 치료를 위한 캄프토테신의 수화된 결정질 에스테르 Download PDFInfo
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- KR20100082358A KR20100082358A KR1020107011223A KR20107011223A KR20100082358A KR 20100082358 A KR20100082358 A KR 20100082358A KR 1020107011223 A KR1020107011223 A KR 1020107011223A KR 20107011223 A KR20107011223 A KR 20107011223A KR 20100082358 A KR20100082358 A KR 20100082358A
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- South Korea
- Prior art keywords
- cancer
- camptothecin
- crystalline
- hydrate
- crystalline camptothecin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
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| US11/923,727 US7572803B2 (en) | 2007-10-25 | 2007-10-25 | Hydrated crystalline esters of camptothecin |
| US11/923,727 | 2007-10-25 |
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| KR20100082358A true KR20100082358A (ko) | 2010-07-16 |
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| KR1020107011223A Ceased KR20100082358A (ko) | 2007-10-25 | 2008-10-24 | 암 치료를 위한 캄프토테신의 수화된 결정질 에스테르 |
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| EP (1) | EP2205605B1 (enExample) |
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| MX (1) | MX2010004332A (enExample) |
| RU (1) | RU2483071C2 (enExample) |
| WO (1) | WO2009055633A1 (enExample) |
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|---|---|---|---|---|
| US20130121921A1 (en) | 2011-11-11 | 2013-05-16 | The Christus Stehlin Foundation For Cancer Research | Rodent Therapeutic Model And Methods |
| US9387257B2 (en) * | 2014-01-17 | 2016-07-12 | Academia Sinica | Lung cancer specific peptides for targeted drug delivery and molecular imaging |
| US9675609B2 (en) | 2015-11-11 | 2017-06-13 | Cao Pharmaceuticals Inc. | Nano- and micro-sized particles of 20-camptothecin or derivative thereof and pharmaceutical compositions containing same, and treatment of cancers therewith |
| US20220395497A1 (en) * | 2019-11-20 | 2022-12-15 | Vivacitas Oncology, Inc. | Cancer Treatment Using Camptothecin Derivatives |
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| US5552154A (en) * | 1989-11-06 | 1996-09-03 | The Stehlin Foundation For Cancer Research | Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof |
| US6080751A (en) * | 1992-01-14 | 2000-06-27 | The Stehlin Foundation For Cancer Research | Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof |
| US5527913A (en) * | 1993-02-25 | 1996-06-18 | The Stehlin Foundation For Cancer Research | Methods for purifying camptothecin compounds |
| US5352789A (en) * | 1993-02-25 | 1994-10-04 | The Stehlin Foundation For Cancer Research | Methods for purifying camptothecin compounds |
| US5731316A (en) | 1996-01-30 | 1998-03-24 | The Stehlin Foundation For Cancer Research | Derivatives of camptothecin and methods of treating cancer using these derivatives |
| US6407118B1 (en) * | 1996-01-30 | 2002-06-18 | The Stehlin Foundation For Cancer Research | Derivatives of camptothecin and methods of treating cancer using these derivatives |
| US6096336A (en) * | 1996-01-30 | 2000-08-01 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US5922877A (en) * | 1997-08-05 | 1999-07-13 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
| USRE38408E1 (en) * | 1997-08-05 | 2004-01-27 | The Stehlin Foundation For Cancer Research | Methods of preparing and purifying 9-nitro-20-camptothecin |
| US6228855B1 (en) * | 1999-08-03 | 2001-05-08 | The Stehlin Foundation For Cancer Research | Aromatic esters of camptothecins and methods to treat cancers |
| US6352996B1 (en) * | 1999-08-03 | 2002-03-05 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US6699875B2 (en) * | 2002-05-06 | 2004-03-02 | The Stehlin Foundation For Cancer Research | Cascade esters of camptothecins and methods of treating cancer using these compounds |
| US6703399B2 (en) * | 2002-05-06 | 2004-03-09 | The Stehlin Foundation For Cancer Research | Halo-alkyl esters of camptothecins and methods of treating cancer using these compounds |
| KR101095382B1 (ko) * | 2003-02-25 | 2011-12-16 | 가부시키가이샤 야쿠르트 혼샤 | 이리노테칸 염산염의 결정다형의 제조방법 |
| TWI333492B (en) * | 2003-11-12 | 2010-11-21 | Smithkline Beecham Cork Ltd | Crystalline topotecan hydrochloride product and preparation thereof |
| WO2007035709A2 (en) * | 2005-09-20 | 2007-03-29 | Scinopharm Singapore Pte, Ltd. | Novel crystal forms of irinotecan hydrochloride |
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2007
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- 2008-10-24 EP EP08841603A patent/EP2205605B1/en not_active Not-in-force
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- 2008-10-24 BR BRPI0816584-0A2A patent/BRPI0816584A2/pt not_active IP Right Cessation
- 2008-10-24 KR KR1020107011223A patent/KR20100082358A/ko not_active Ceased
- 2008-10-24 CN CN200880013536XA patent/CN101730701B/zh not_active Expired - Fee Related
- 2008-10-24 MX MX2010004332A patent/MX2010004332A/es active IP Right Grant
- 2008-10-24 JP JP2010531264A patent/JP5487111B2/ja not_active Expired - Fee Related
- 2008-10-24 WO PCT/US2008/081047 patent/WO2009055633A1/en not_active Ceased
- 2008-10-24 RU RU2010120810/04A patent/RU2483071C2/ru not_active IP Right Cessation
- 2008-10-24 ES ES08841603T patent/ES2396222T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101730701B (zh) | 2013-05-29 |
| ES2396222T3 (es) | 2013-02-20 |
| US20090111845A1 (en) | 2009-04-30 |
| CA2703054C (en) | 2017-08-22 |
| RU2483071C2 (ru) | 2013-05-27 |
| RU2010120810A (ru) | 2011-11-27 |
| BRPI0816584A2 (pt) | 2015-03-03 |
| CN101730701A (zh) | 2010-06-09 |
| MX2010004332A (es) | 2010-05-20 |
| EP2205605A1 (en) | 2010-07-14 |
| CA2703054A1 (en) | 2009-04-30 |
| JP5487111B2 (ja) | 2014-05-07 |
| JP2011500841A (ja) | 2011-01-06 |
| WO2009055633A1 (en) | 2009-04-30 |
| EP2205605B1 (en) | 2012-11-21 |
| US7572803B2 (en) | 2009-08-11 |
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