MX2010002419A - (ciclopropilfenil) feniloxamidas, metodo para su produccion y uso como un medicamento. - Google Patents
(ciclopropilfenil) feniloxamidas, metodo para su produccion y uso como un medicamento.Info
- Publication number
- MX2010002419A MX2010002419A MX2010002419A MX2010002419A MX2010002419A MX 2010002419 A MX2010002419 A MX 2010002419A MX 2010002419 A MX2010002419 A MX 2010002419A MX 2010002419 A MX2010002419 A MX 2010002419A MX 2010002419 A MX2010002419 A MX 2010002419A
- Authority
- MX
- Mexico
- Prior art keywords
- phenyl
- oxalamides
- cyclopropyl
- medicament
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/56—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
La invención se refiere a (ciclopropilfenil)feniloxamidas y sus sales fisiológicamente toleradas. La invención se refiere a compuestos de la fórmula I (Ver fórmula I) en donde R1, R2, R3, R4, R5, R6, R7, R8 y m tienen los significados indicados, y a sus sales fisiológicamente toleradas. Los compuestos son adecuados, por ejemplo, para el tratamiento de la diabetes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07291131 | 2007-09-21 | ||
PCT/EP2008/007217 WO2009039942A1 (de) | 2007-09-21 | 2008-09-04 | (cyclopropyl-phenyl)-phenyl-oxalamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010002419A true MX2010002419A (es) | 2010-03-30 |
Family
ID=39111440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002419A MX2010002419A (es) | 2007-09-21 | 2008-09-04 | (ciclopropilfenil) feniloxamidas, metodo para su produccion y uso como un medicamento. |
Country Status (20)
Country | Link |
---|---|
US (1) | US8148375B2 (es) |
EP (1) | EP2203415B1 (es) |
JP (1) | JP2011509239A (es) |
KR (1) | KR20100075444A (es) |
CN (1) | CN101796018A (es) |
AR (1) | AR070753A1 (es) |
AU (1) | AU2008303975B2 (es) |
BR (1) | BRPI0817198A2 (es) |
CA (1) | CA2700025A1 (es) |
CL (1) | CL2008002768A1 (es) |
CO (1) | CO6260061A2 (es) |
IL (1) | IL204556A (es) |
MA (1) | MA31979B1 (es) |
MX (1) | MX2010002419A (es) |
NZ (1) | NZ584050A (es) |
RU (1) | RU2010115747A (es) |
TW (1) | TW200934751A (es) |
UY (1) | UY31351A1 (es) |
WO (1) | WO2009039942A1 (es) |
ZA (1) | ZA201001014B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
EP2612669A4 (en) | 2010-08-31 | 2014-05-14 | Snu R&Db Foundation | USING THE FÖTAL REPROGRAMMING OF A PPAR AGONIST |
SG188585A1 (en) | 2010-09-22 | 2013-04-30 | Eisai R&D Man Co Ltd | Cyclopropane compound |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
IN2015DN03795A (es) | 2012-10-24 | 2015-10-02 | Inserm Inst Nat De La Santé Et De La Rech Médicale | |
EP3076959B1 (en) | 2013-12-04 | 2018-07-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
WO2015119899A1 (en) | 2014-02-06 | 2015-08-13 | Merck Sharp & Dohme Corp. | Antidiabetic compounds |
CA2964504C (en) | 2014-10-23 | 2022-08-23 | Eisai R&D Management Co., Ltd. | Oral dosage form comprising a cyclopropanecarboxamide derivative for use in treating insomnia |
EP3273981B1 (en) | 2015-03-24 | 2020-04-29 | INSERM - Institut National de la Santé et de la Recherche Médicale | Method and pharmaceutical composition for use in the treatment of diabetes |
WO2019160882A1 (en) | 2018-02-13 | 2019-08-22 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
US10899735B2 (en) | 2018-04-19 | 2021-01-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
JP7105359B2 (ja) | 2018-07-13 | 2022-07-22 | ギリアード サイエンシーズ, インコーポレイテッド | Pd-1/pd-l1阻害剤 |
US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
CN109574920B (zh) * | 2018-12-25 | 2022-03-04 | 药大制药有限公司 | 3-腈基-6环丙基吡啶类ido1抑制剂及其用途 |
WO2020149129A1 (ja) * | 2019-01-15 | 2020-07-23 | 株式会社カネカ | 非対称化合物の製造方法 |
US20220257624A1 (en) * | 2019-05-31 | 2022-08-18 | Avolynt | Compositions and methods for treating metabolic disease |
AU2020363377A1 (en) | 2019-10-07 | 2022-04-21 | Kallyope, Inc. | GPR119 agonists |
EP4153589A4 (en) | 2020-05-19 | 2024-06-12 | Kallyope, Inc. | AMPK ACTIVATORS |
WO2021263039A1 (en) | 2020-06-26 | 2021-12-30 | Kallyope, Inc. | Ampk activators |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6890568B2 (en) * | 1999-05-24 | 2005-05-10 | Grant Pierce | Method for management of blood glucose levels |
WO2002096876A1 (en) * | 2001-05-25 | 2002-12-05 | Boehringer Ingelheim Pharmaceuticals, Inc. | Carbamate and oxamide compounds as inhibitors of cytokine production |
US20050124667A1 (en) * | 2003-10-30 | 2005-06-09 | Eric Sartori | Oxamide inhibitors of plasminogen activator inhibitor-1 |
-
2008
- 2008-09-04 EP EP08785814.8A patent/EP2203415B1/de active Active
- 2008-09-04 BR BRPI0817198 patent/BRPI0817198A2/pt not_active IP Right Cessation
- 2008-09-04 CA CA2700025A patent/CA2700025A1/en not_active Abandoned
- 2008-09-04 CN CN200880105479A patent/CN101796018A/zh active Pending
- 2008-09-04 JP JP2010525226A patent/JP2011509239A/ja not_active Abandoned
- 2008-09-04 KR KR1020107006033A patent/KR20100075444A/ko not_active Application Discontinuation
- 2008-09-04 NZ NZ584050A patent/NZ584050A/en not_active IP Right Cessation
- 2008-09-04 MX MX2010002419A patent/MX2010002419A/es not_active Application Discontinuation
- 2008-09-04 AU AU2008303975A patent/AU2008303975B2/en not_active Expired - Fee Related
- 2008-09-04 RU RU2010115747/04A patent/RU2010115747A/ru unknown
- 2008-09-04 WO PCT/EP2008/007217 patent/WO2009039942A1/de active Application Filing
- 2008-09-16 CL CL2008002768A patent/CL2008002768A1/es unknown
- 2008-09-18 AR ARP080104057A patent/AR070753A1/es not_active Application Discontinuation
- 2008-09-18 TW TW097135730A patent/TW200934751A/zh unknown
- 2008-09-19 UY UY31351A patent/UY31351A1/es not_active Application Discontinuation
-
2010
- 2010-02-11 ZA ZA201001014A patent/ZA201001014B/xx unknown
- 2010-03-16 US US12/724,517 patent/US8148375B2/en not_active Expired - Fee Related
- 2010-03-16 IL IL204556A patent/IL204556A/en not_active IP Right Cessation
- 2010-03-16 CO CO10030967A patent/CO6260061A2/es not_active Application Discontinuation
- 2010-03-19 MA MA32712A patent/MA31979B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
RU2010115747A (ru) | 2011-10-27 |
NZ584050A (en) | 2011-09-30 |
US8148375B2 (en) | 2012-04-03 |
IL204556A0 (en) | 2010-11-30 |
JP2011509239A (ja) | 2011-03-24 |
UY31351A1 (es) | 2009-04-30 |
CL2008002768A1 (es) | 2009-03-06 |
ZA201001014B (en) | 2010-10-27 |
BRPI0817198A2 (pt) | 2015-03-17 |
AU2008303975B2 (en) | 2013-05-16 |
MA31979B1 (fr) | 2011-01-03 |
WO2009039942A1 (de) | 2009-04-02 |
EP2203415A1 (de) | 2010-07-07 |
CO6260061A2 (es) | 2011-03-22 |
TW200934751A (en) | 2009-08-16 |
CN101796018A (zh) | 2010-08-04 |
US20100261644A1 (en) | 2010-10-14 |
AU2008303975A1 (en) | 2009-04-02 |
KR20100075444A (ko) | 2010-07-02 |
AR070753A1 (es) | 2010-05-05 |
CA2700025A1 (en) | 2009-04-02 |
EP2203415B1 (de) | 2016-10-26 |
IL204556A (en) | 2013-06-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |