MX2009012506A - Composiciones, sintesis, y metodos para utilizar agentes antipsicoticos atipicos basados en quinolinona. - Google Patents

Composiciones, sintesis, y metodos para utilizar agentes antipsicoticos atipicos basados en quinolinona.

Info

Publication number
MX2009012506A
MX2009012506A MX2009012506A MX2009012506A MX2009012506A MX 2009012506 A MX2009012506 A MX 2009012506A MX 2009012506 A MX2009012506 A MX 2009012506A MX 2009012506 A MX2009012506 A MX 2009012506A MX 2009012506 A MX2009012506 A MX 2009012506A
Authority
MX
Mexico
Prior art keywords
synthesis
compositions
methods
atypical antipsychotic
antipsychotic agents
Prior art date
Application number
MX2009012506A
Other languages
English (en)
Inventor
Laxminarayan Bhat
Prabhu P Mohapatra
Seema Rani Bhat
Original Assignee
Reviva Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reviva Pharmaceuticals Inc filed Critical Reviva Pharmaceuticals Inc
Publication of MX2009012506A publication Critical patent/MX2009012506A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

La presente invención proporciona derivados novedosos de quinolinona que pueden utilizarse ventajosamente para tratar la esquizofrenia y psicosis relacionadas tales como desorden bipolar maniaco agudo, desorden autista, y depresión.
MX2009012506A 2007-05-21 2008-05-21 Composiciones, sintesis, y metodos para utilizar agentes antipsicoticos atipicos basados en quinolinona. MX2009012506A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93926207P 2007-05-21 2007-05-21
PCT/US2008/064433 WO2008144764A1 (en) 2007-05-21 2008-05-21 Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

Publications (1)

Publication Number Publication Date
MX2009012506A true MX2009012506A (es) 2009-12-09

Family

ID=40072982

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012506A MX2009012506A (es) 2007-05-21 2008-05-21 Composiciones, sintesis, y metodos para utilizar agentes antipsicoticos atipicos basados en quinolinona.

Country Status (13)

Country Link
US (1) US8247420B2 (es)
EP (1) EP2162135A4 (es)
JP (1) JP5466147B2 (es)
CN (1) CN101754761B (es)
AU (1) AU2008254585B2 (es)
BR (1) BRPI0811844A2 (es)
CA (1) CA2688784A1 (es)
IL (1) IL202003A (es)
MX (1) MX2009012506A (es)
NZ (1) NZ582124A (es)
RU (1) RU2497819C2 (es)
WO (1) WO2008144764A1 (es)
ZA (1) ZA200908753B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE031053T2 (en) * 2009-02-26 2017-06-28 Reviva Pharmaceuticals Inc Preparations, synthesis and methods of application of arylpiperazine derivatives
EP4124616A1 (en) 2009-06-25 2023-02-01 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
WO2016115039A1 (en) 2015-01-12 2016-07-21 Reviva Pharmaceuticals Inc. Methods for treating pulmonary hypertension
CN106749219A (zh) * 2015-11-20 2017-05-31 江苏恩华药业股份有限公司 一种内酰胺类衍生物及其应用
RU2667954C2 (ru) * 2016-03-04 2018-09-25 Общество С Ограниченной Ответственностью "Валентек" Фармацевтическая композиция для лечения функциональных психических расстройств
KR102444803B1 (ko) * 2017-05-04 2022-09-19 익스시바 게엠베하 신규 조성물, 조합 및 그의 방법을 갖는 표적 약물 구제
EP3642184A1 (en) * 2017-06-22 2020-04-29 Curadev Pharma Limited Small molecule modulators of human sting
BR112019027127A2 (pt) 2017-06-22 2020-07-07 Curadev Pharma Limited moduladores de sting humano de molécula pequena
EP3761983A1 (en) 2018-03-05 2021-01-13 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN115784983A (zh) * 2022-12-05 2023-03-14 井冈山大学 6-胺烷氧基-3,4-二氢喹啉酮衍生物及制备方法和应用

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JPS5649364A (en) * 1979-09-28 1981-05-02 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DE3442570A1 (de) * 1984-11-22 1986-05-22 Hoechst Ag, 6230 Frankfurt Neue substituierte phenylpiperazinderivate, verfahren zu deren herstellung und die verwendung substituierter phenylpiperazinderivate als aggressionshemmer fuer tiere
DE3815221C2 (de) * 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
JP2608788B2 (ja) * 1988-10-31 1997-05-14 大塚製薬 株式会社 精神分裂病治療剤
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Also Published As

Publication number Publication date
NZ582124A (en) 2012-07-27
BRPI0811844A2 (pt) 2014-11-18
EP2162135A4 (en) 2012-02-22
EP2162135A1 (en) 2010-03-17
AU2008254585A1 (en) 2008-11-27
CA2688784A1 (en) 2008-11-27
CN101754761B (zh) 2014-06-18
IL202003A0 (en) 2010-06-16
US8247420B2 (en) 2012-08-21
CN101754761A (zh) 2010-06-23
ZA200908753B (en) 2010-07-28
RU2497819C2 (ru) 2013-11-10
WO2008144764A1 (en) 2008-11-27
IL202003A (en) 2013-11-28
JP2010528042A (ja) 2010-08-19
AU2008254585B2 (en) 2013-09-26
RU2009147268A (ru) 2011-06-27
JP5466147B2 (ja) 2014-04-09
US20080293736A1 (en) 2008-11-27

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