ZA200908753B - Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents - Google Patents

Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

Info

Publication number
ZA200908753B
ZA200908753B ZA200908753A ZA200908753A ZA200908753B ZA 200908753 B ZA200908753 B ZA 200908753B ZA 200908753 A ZA200908753 A ZA 200908753A ZA 200908753 A ZA200908753 A ZA 200908753A ZA 200908753 B ZA200908753 B ZA 200908753B
Authority
ZA
South Africa
Prior art keywords
synthesis
compositions
methods
atypical antipsychotic
antipsychotic agents
Prior art date
Application number
ZA200908753A
Other languages
English (en)
Inventor
Laxminarayan Bhat
Prabhu P Mohapatra
Seema Rani Bhat
Original Assignee
Reviva Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reviva Pharmaceuticals Inc filed Critical Reviva Pharmaceuticals Inc
Publication of ZA200908753B publication Critical patent/ZA200908753B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA200908753A 2007-05-21 2009-01-01 Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents ZA200908753B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93926207P 2007-05-21 2007-05-21

Publications (1)

Publication Number Publication Date
ZA200908753B true ZA200908753B (en) 2010-07-28

Family

ID=40072982

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200908753A ZA200908753B (en) 2007-05-21 2009-01-01 Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

Country Status (13)

Country Link
US (1) US8247420B2 (xx)
EP (1) EP2162135A4 (xx)
JP (1) JP5466147B2 (xx)
CN (1) CN101754761B (xx)
AU (1) AU2008254585B2 (xx)
BR (1) BRPI0811844A2 (xx)
CA (1) CA2688784A1 (xx)
IL (1) IL202003A (xx)
MX (1) MX2009012506A (xx)
NZ (1) NZ582124A (xx)
RU (1) RU2497819C2 (xx)
WO (1) WO2008144764A1 (xx)
ZA (1) ZA200908753B (xx)

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* Cited by examiner, † Cited by third party
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KR101705727B1 (ko) * 2009-02-26 2017-02-10 레비바 파마슈티칼스, 아이엔씨. 아릴피페라진 유도체의 조성물, 합성, 및 사용 방법
HRP20171415T4 (hr) 2009-06-25 2023-03-03 Alkermes Pharma Ireland Limited Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
CN107206007B (zh) 2015-01-12 2021-08-10 雷维瓦药品公司 用于治疗肺高血压的方法
CN106749219A (zh) * 2015-11-20 2017-05-31 江苏恩华药业股份有限公司 一种内酰胺类衍生物及其应用
RU2667954C2 (ru) * 2016-03-04 2018-09-25 Общество С Ограниченной Ответственностью "Валентек" Фармацевтическая композиция для лечения функциональных психических расстройств
BR112019022902A2 (pt) * 2017-05-04 2020-05-19 Exciva GmbH composição, composição farmacêutica, uso da composição terapeuticamente eficaz, método e uso de uma composição terapeuticamente eficaz em um método de tratamento
CN111132972A (zh) 2017-06-22 2020-05-08 克拉德夫制药有限公司 人sting的小分子调节剂
WO2018234805A1 (en) * 2017-06-22 2018-12-27 Curadev Pharma Limited SMALL MOLECULAR MODULATORS OF HUMAN STING
JP7384812B2 (ja) 2018-03-05 2023-11-21 アルカームス ファーマ アイルランド リミテッド アリピプラゾール投与戦略
CN115784983A (zh) * 2022-12-05 2023-03-14 井冈山大学 6-胺烷氧基-3,4-二氢喹啉酮衍生物及制备方法和应用

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JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
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KR101041551B1 (ko) 2004-10-08 2011-06-15 수벤 라이프 사이언시스 리미티드 아리피프라졸 제조를 위해 유용한 신규 중간체와 신규중간체 및 아리피프라졸 제조 방법

Also Published As

Publication number Publication date
AU2008254585A1 (en) 2008-11-27
IL202003A0 (en) 2010-06-16
JP2010528042A (ja) 2010-08-19
RU2009147268A (ru) 2011-06-27
CA2688784A1 (en) 2008-11-27
AU2008254585B2 (en) 2013-09-26
US20080293736A1 (en) 2008-11-27
US8247420B2 (en) 2012-08-21
EP2162135A4 (en) 2012-02-22
BRPI0811844A2 (pt) 2014-11-18
CN101754761B (zh) 2014-06-18
EP2162135A1 (en) 2010-03-17
JP5466147B2 (ja) 2014-04-09
CN101754761A (zh) 2010-06-23
NZ582124A (en) 2012-07-27
WO2008144764A1 (en) 2008-11-27
IL202003A (en) 2013-11-28
MX2009012506A (es) 2009-12-09
RU2497819C2 (ru) 2013-11-10

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