ZA200908753B - Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents - Google Patents

Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

Info

Publication number
ZA200908753B
ZA200908753B ZA200908753A ZA200908753A ZA200908753B ZA 200908753 B ZA200908753 B ZA 200908753B ZA 200908753 A ZA200908753 A ZA 200908753A ZA 200908753 A ZA200908753 A ZA 200908753A ZA 200908753 B ZA200908753 B ZA 200908753B
Authority
ZA
South Africa
Prior art keywords
synthesis
compositions
methods
atypical antipsychotic
antipsychotic agents
Prior art date
Application number
ZA200908753A
Other languages
English (en)
Inventor
Laxminarayan Bhat
Prabhu P Mohapatra
Seema Rani Bhat
Original Assignee
Reviva Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reviva Pharmaceuticals Inc filed Critical Reviva Pharmaceuticals Inc
Publication of ZA200908753B publication Critical patent/ZA200908753B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
ZA200908753A 2007-05-21 2009-01-01 Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents ZA200908753B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93926207P 2007-05-21 2007-05-21

Publications (1)

Publication Number Publication Date
ZA200908753B true ZA200908753B (en) 2010-07-28

Family

ID=40072982

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200908753A ZA200908753B (en) 2007-05-21 2009-01-01 Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

Country Status (13)

Country Link
US (1) US8247420B2 (xx)
EP (1) EP2162135A4 (xx)
JP (1) JP5466147B2 (xx)
CN (1) CN101754761B (xx)
AU (1) AU2008254585B2 (xx)
BR (1) BRPI0811844A2 (xx)
CA (1) CA2688784A1 (xx)
IL (1) IL202003A (xx)
MX (1) MX2009012506A (xx)
NZ (1) NZ582124A (xx)
RU (1) RU2497819C2 (xx)
WO (1) WO2008144764A1 (xx)
ZA (1) ZA200908753B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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AU2010217772B2 (en) * 2009-02-26 2014-10-23 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of utilizing arylpiperazine derivatives
EP3309151A1 (en) 2009-06-25 2018-04-18 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
JP6787926B2 (ja) 2015-01-12 2020-11-18 レビバ ファーマシューティカルズ,インコーポレイティド 肺高血圧症の治療方法
CN106749219A (zh) * 2015-11-20 2017-05-31 江苏恩华药业股份有限公司 一种内酰胺类衍生物及其应用
RU2667954C2 (ru) * 2016-03-04 2018-09-25 Общество С Ограниченной Ответственностью "Валентек" Фармацевтическая композиция для лечения функциональных психических расстройств
KR102444803B1 (ko) * 2017-05-04 2022-09-19 익스시바 게엠베하 신규 조성물, 조합 및 그의 방법을 갖는 표적 약물 구제
WO2018234805A1 (en) * 2017-06-22 2018-12-27 Curadev Pharma Limited SMALL MOLECULAR MODULATORS OF HUMAN STING
UA125730C2 (uk) 2017-06-22 2022-05-25 Курадев Фарма Лімітед Низькомолекулярні модулятори sting людини
AU2019230014A1 (en) 2018-03-05 2020-09-17 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN115784983A (zh) * 2022-12-05 2023-03-14 井冈山大学 6-胺烷氧基-3,4-二氢喹啉酮衍生物及制备方法和应用
CN116496234A (zh) * 2023-02-09 2023-07-28 江苏润安制药有限公司 一种盐酸乌拉地尔关键中间体的制备方法

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DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
US5006528A (en) 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
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BR0314393A (pt) * 2002-09-17 2005-07-19 Warner Lambert Co Piperazinas heterocìclicas substituìdas para o tratamento de esquizofrenia
EP1480953B2 (en) 2003-01-09 2010-08-18 Otsuka Pharmaceutical Co., Ltd. Process for preparing aripiprazole
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US7872132B2 (en) 2004-10-08 2011-01-18 Suven Life Sciences Limited Intermediates useful for the preparation of aripiprazole and methods for the preparation of the novel intermediates and aripiprazole

Also Published As

Publication number Publication date
NZ582124A (en) 2012-07-27
JP2010528042A (ja) 2010-08-19
EP2162135A1 (en) 2010-03-17
BRPI0811844A2 (pt) 2014-11-18
RU2009147268A (ru) 2011-06-27
RU2497819C2 (ru) 2013-11-10
US8247420B2 (en) 2012-08-21
CN101754761B (zh) 2014-06-18
CA2688784A1 (en) 2008-11-27
EP2162135A4 (en) 2012-02-22
US20080293736A1 (en) 2008-11-27
AU2008254585A1 (en) 2008-11-27
CN101754761A (zh) 2010-06-23
AU2008254585B2 (en) 2013-09-26
IL202003A0 (en) 2010-06-16
WO2008144764A1 (en) 2008-11-27
MX2009012506A (es) 2009-12-09
IL202003A (en) 2013-11-28
JP5466147B2 (ja) 2014-04-09

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