MX2009011412A - Compuestos moduladores de receptores de crth2 y/o pgd2 y su uso para el tratamiento de asma e inflamacion alergica. - Google Patents

Compuestos moduladores de receptores de crth2 y/o pgd2 y su uso para el tratamiento de asma e inflamacion alergica.

Info

Publication number
MX2009011412A
MX2009011412A MX2009011412A MX2009011412A MX2009011412A MX 2009011412 A MX2009011412 A MX 2009011412A MX 2009011412 A MX2009011412 A MX 2009011412A MX 2009011412 A MX2009011412 A MX 2009011412A MX 2009011412 A MX2009011412 A MX 2009011412A
Authority
MX
Mexico
Prior art keywords
compounds
crth2
treating asthma
allergic inflammation
linkage selected
Prior art date
Application number
MX2009011412A
Other languages
English (en)
Spanish (es)
Inventor
Wang Shen
Julio C Medina
Jiwen Liu
Yingcai Wang
Sarah E Lively
Michael G Johnson
An-Rong Li
Xuemei Wang
Matthew Brown
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2009011412A publication Critical patent/MX2009011412A/es

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    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
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    • C07D471/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
MX2009011412A 2007-05-02 2008-05-01 Compuestos moduladores de receptores de crth2 y/o pgd2 y su uso para el tratamiento de asma e inflamacion alergica. MX2009011412A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92754507P 2007-05-02 2007-05-02
PCT/US2008/005611 WO2008137027A2 (en) 2007-05-02 2008-05-01 Compounds as crth2 and/or pgd2 receptors modulators and their use for treating asthma and allergic inflammation

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MX2009011412A true MX2009011412A (es) 2009-11-05

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US (1) US7960567B2 (cg-RX-API-DMAC7.html)
EP (1) EP2164828B1 (cg-RX-API-DMAC7.html)
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AU (1) AU2008248201B2 (cg-RX-API-DMAC7.html)
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MX (1) MX2009011412A (cg-RX-API-DMAC7.html)
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US8168678B2 (en) 2008-02-01 2012-05-01 Panmira Pharmaceuticals, Inc. N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors
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TWI403319B (zh) 2008-07-03 2013-08-01 Panmira Pharmaceuticals Llc 前列腺素ｄ2受體之雜烷基拮抗劑
WO2010006939A1 (en) * 2008-07-15 2010-01-21 F. Hoffmann-La Roche Ag Aminotetrahydroindazoloacetic acids
EP2307383B1 (en) * 2008-07-15 2012-05-16 F. Hoffmann-La Roche AG Aminotetrahydroindazoloacetic acids
GB2463788B (en) 2008-09-29 2010-12-15 Amira Pharmaceuticals Inc Heteroaryl antagonists of prostaglandin D2 receptors
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