MX2009008413A - Tratamiento y prevencion de enfermedades neurodegenerativas usando terapia genica. - Google Patents
Tratamiento y prevencion de enfermedades neurodegenerativas usando terapia genica.Info
- Publication number
- MX2009008413A MX2009008413A MX2009008413A MX2009008413A MX2009008413A MX 2009008413 A MX2009008413 A MX 2009008413A MX 2009008413 A MX2009008413 A MX 2009008413A MX 2009008413 A MX2009008413 A MX 2009008413A MX 2009008413 A MX2009008413 A MX 2009008413A
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- Mexico
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En este documento se proporcionan composiciones y métodos para tratar y/o prevenir una enfermedad neurodegenerativa, tal como enfermedad de Alzheimer. En aspectos particulares, las composiciones administradas en este documento codifican un elemento de respuesta inmune celular. Las composiciones pueden prepararse y administrarse de manera tal que la secuencia codificante del elemento de respuesta inmune celular se expresa en el sujeto al que se administra la composición. Las composiciones incluyen sistemas de expresión, sistemas de suministro, y ciertos genes de elementos de respuesta inmune celular.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90013807P | 2007-02-06 | 2007-02-06 | |
PCT/US2008/052953 WO2008097927A2 (en) | 2007-02-06 | 2008-02-04 | Treatment and prevention of neurodegenerative diseases using gene therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009008413A true MX2009008413A (es) | 2009-11-02 |
Family
ID=39682371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009008413A MX2009008413A (es) | 2007-02-06 | 2008-02-04 | Tratamiento y prevencion de enfermedades neurodegenerativas usando terapia genica. |
Country Status (13)
Country | Link |
---|---|
US (2) | US8247385B2 (es) |
EP (1) | EP2114153B1 (es) |
JP (1) | JP5829377B2 (es) |
KR (2) | KR101661356B1 (es) |
CN (2) | CN101652063A (es) |
AU (1) | AU2008213999B2 (es) |
CA (1) | CA2677273A1 (es) |
IL (1) | IL200151A (es) |
MX (1) | MX2009008413A (es) |
NZ (1) | NZ579050A (es) |
RU (1) | RU2471487C2 (es) |
WO (1) | WO2008097927A2 (es) |
ZA (1) | ZA200906165B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120014987A1 (en) * | 2009-03-26 | 2012-01-19 | Yoh Matsumoto | Dna vaccine for alzheimer's disease |
US9173928B2 (en) | 2009-03-26 | 2015-11-03 | Yoh Matsumoto | DNA vaccine for Alzheimer's disease |
KR101367568B1 (ko) * | 2011-05-31 | 2014-02-27 | 임우석 | Abc 수송체 조절을 통한 퇴행성신경질환에서 이상단백질 조절 |
CN106714845A (zh) * | 2014-08-11 | 2017-05-24 | 得克萨斯州大学系统董事会 | 通过crispr/cas9介导的基因编辑预防肌营养不良 |
RU2652312C2 (ru) * | 2016-01-20 | 2018-04-25 | Селл энд Джин Терапи Лтд | Линейка биологически активных генно-терапевтических субстанций на основе гена tgfb1 для коррекции патологических состояний клеток органов и тканей и органов и тканей человека, способ получения и использования |
CN105748518B (zh) * | 2016-03-21 | 2019-06-07 | 大连大学 | 包含脂肪干细胞提取物的抗衰老组合物 |
US10829528B2 (en) * | 2016-07-20 | 2020-11-10 | Vib Vzw | Therapeutic agents for neurological and psychiatric disorders |
US12068059B2 (en) | 2017-01-25 | 2024-08-20 | Whitehead Institute For Biomedical Research | Methods for building genomic networks and uses thereof |
EP3754025A4 (en) * | 2018-01-24 | 2022-01-26 | Slbigen Inc. | MESENCHYMAL STEM CELLS WITH BRAIN-DERIVED NEUROTROPHIC FACTOR EXPRESSION AND THEIR USE |
US20210079050A1 (en) * | 2018-02-20 | 2021-03-18 | Carmel Haifa University Economic Corporation Ltd. | Compositions and methods for delivery and expression of small inhibitory peptides and use thereof |
IT201800003279A1 (it) * | 2018-03-05 | 2019-09-05 | Consiglio Nazionale Ricerche | Peptide neurotrofico per il trattamento terapeutico di patologie neurodegenerative e/o infiammatorie. |
CN109942714B (zh) * | 2019-04-02 | 2022-07-08 | 中国药科大学 | 一种功能多肽及应用 |
GB2620875B (en) | 2019-04-19 | 2024-05-08 | Synerkine Pharma B V | A fusion protein comprising IL13 |
BR112022007010A2 (pt) * | 2019-10-16 | 2022-07-12 | Univ Cornell | Terapia gênica para doença de alzheimer |
EP3992292A4 (en) * | 2020-02-28 | 2023-06-21 | Rznomics Inc. | APOE4 RNA SPECIFIC TRANS-SPLICING RIBOZYME AND USE THEREOF |
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US4650764A (en) | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
EP0391960B1 (en) | 1987-12-11 | 1994-08-17 | Whitehead Institute For Biomedical Research | Genetic modification of endothelial cells |
JPH04507041A (ja) | 1988-12-13 | 1992-12-10 | アメリカ合衆国 | 遺伝工学により修飾された内皮細胞およびその利用方法 |
EP1026253B2 (en) | 1989-03-21 | 2012-12-19 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
US5437994A (en) | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
US5676954A (en) | 1989-11-03 | 1997-10-14 | Vanderbilt University | Method of in vivo delivery of functioning foreign genes |
US6326198B1 (en) | 1990-06-14 | 2001-12-04 | Regents Of The University Of Michigan | Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
US20030125519A1 (en) | 1990-08-27 | 2003-07-03 | Peter Besmer | Ligand for the c-kit receptor and methods of use thereof |
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JP3249516B2 (ja) | 1990-10-31 | 2002-01-21 | ソマティクス セラピー コーポレイション | 遺伝子治療のためのレトロウイルスのベクター |
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US6080728A (en) | 1996-07-16 | 2000-06-27 | Mixson; A. James | Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy |
EP0961830A1 (en) * | 1997-01-29 | 1999-12-08 | Neurosearch A/S | EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES |
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US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
WO2002007774A2 (en) * | 2000-07-19 | 2002-01-31 | The Regents Of The University Of California | Methods for therapy of neurodegenerative disease of the brain |
RU2238947C2 (ru) | 1998-07-14 | 2004-10-27 | Янссен Фармацевтика Н.В. | Нейротрофический фактор роста человека (эновин), кодирующая его выделенная молекула нуклеиновой кислоты, вектор (варианты), фармацевтическая композиция (варианты), антитело, способ обнаружения фактора роста, набор, способ идентификации агониста или антагониста (варианты) |
BR9912819A (pt) | 1998-07-14 | 2001-05-02 | Janssen Pharmaceutica Nv | Fator de crescimento neurotrófico |
CA2407074A1 (en) | 2000-04-21 | 2001-11-01 | Jukka Hartikka | Compositions and methods for in vivo delivery of polynucleotide-based therapeutics |
CN100534436C (zh) * | 2001-11-21 | 2009-09-02 | 利兰·斯坦福青年大学托管委员会 | 多核苷酸 |
GB0212648D0 (en) * | 2002-05-31 | 2002-07-10 | Immunoclin Lab Ltd | Treatment with cytokines |
US20060073119A1 (en) * | 2004-09-01 | 2006-04-06 | Avigen, Inc. | Methods for treating neurodegenerative disorders |
JP4855268B2 (ja) * | 2004-11-30 | 2012-01-18 | アンジェスMg株式会社 | アルツハイマー治療剤 |
EP1841455A1 (en) * | 2005-01-24 | 2007-10-10 | Amgen Inc. | Humanized anti-amyloid antibody |
JPWO2007139178A1 (ja) * | 2006-05-31 | 2009-10-15 | ディナベック株式会社 | アルツハイマー病治療薬 |
-
2008
- 2008-02-04 JP JP2009549194A patent/JP5829377B2/ja not_active Expired - Fee Related
- 2008-02-04 WO PCT/US2008/052953 patent/WO2008097927A2/en active Application Filing
- 2008-02-04 KR KR1020097018535A patent/KR101661356B1/ko active IP Right Grant
- 2008-02-04 US US12/025,684 patent/US8247385B2/en not_active Expired - Fee Related
- 2008-02-04 CN CN200880010918A patent/CN101652063A/zh active Pending
- 2008-02-04 KR KR1020147021915A patent/KR20140102327A/ko not_active Application Discontinuation
- 2008-02-04 CA CA002677273A patent/CA2677273A1/en not_active Abandoned
- 2008-02-04 CN CN201710045905.4A patent/CN106890342B/zh not_active Expired - Fee Related
- 2008-02-04 MX MX2009008413A patent/MX2009008413A/es active IP Right Grant
- 2008-02-04 AU AU2008213999A patent/AU2008213999B2/en not_active Ceased
- 2008-02-04 NZ NZ579050A patent/NZ579050A/xx not_active IP Right Cessation
- 2008-02-04 EP EP08728962.5A patent/EP2114153B1/en active Active
- 2008-02-04 RU RU2009132196/15A patent/RU2471487C2/ru active
-
2009
- 2009-07-30 IL IL200151A patent/IL200151A/en active IP Right Grant
- 2009-09-04 ZA ZA2009/06165A patent/ZA200906165B/en unknown
-
2012
- 2012-07-17 US US13/551,495 patent/US20130231632A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2009132196A (ru) | 2011-03-20 |
RU2471487C2 (ru) | 2013-01-10 |
EP2114153B1 (en) | 2016-11-23 |
KR20140102327A (ko) | 2014-08-21 |
US8247385B2 (en) | 2012-08-21 |
AU2008213999B2 (en) | 2014-04-17 |
JP2010518105A (ja) | 2010-05-27 |
ZA200906165B (en) | 2012-02-29 |
CN106890342A (zh) | 2017-06-27 |
IL200151A (en) | 2015-06-30 |
EP2114153A4 (en) | 2011-05-11 |
US20080292603A1 (en) | 2008-11-27 |
WO2008097927A3 (en) | 2008-12-18 |
US20130231632A1 (en) | 2013-09-05 |
CN101652063A (zh) | 2010-02-17 |
WO2008097927A2 (en) | 2008-08-14 |
IL200151A0 (en) | 2010-04-15 |
KR101661356B1 (ko) | 2016-09-30 |
JP5829377B2 (ja) | 2015-12-09 |
KR20090118956A (ko) | 2009-11-18 |
AU2008213999A1 (en) | 2008-08-14 |
EP2114153A2 (en) | 2009-11-11 |
CA2677273A1 (en) | 2008-08-14 |
CN106890342B (zh) | 2022-09-23 |
NZ579050A (en) | 2012-10-26 |
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