MX2009004551A - Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo. - Google Patents

Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo.

Info

Publication number
MX2009004551A
MX2009004551A MX2009004551A MX2009004551A MX2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A
Authority
MX
Mexico
Prior art keywords
microcapsules
sustained
preparation
initial burst
good initial
Prior art date
Application number
MX2009004551A
Other languages
English (en)
Inventor
Nak-Hyun Lim
Jung-Kwoun Kim
Hyung-Joon Jung
Se-Yeon Kim
Goo-Young Jung
Kyung-Hoi Cha
Mork-Soon Park
Original Assignee
Dong Kook Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Kook Pharm Co Ltd filed Critical Dong Kook Pharm Co Ltd
Publication of MX2009004551A publication Critical patent/MX2009004551A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe un método para preparar una formulación de liberación sostenida más prolongada que contiene sustancias bioactivas. Más particularmente, la presente invención proporciona un método para preparar microcápsulas de liberación sostenida más prolongada el cual comprende: adicionar una emulsión que incluye sustancias bioactivas, polímero biocompatible y polivinilpirrolidona a una solución acuosa.
MX2009004551A 2006-11-27 2007-11-21 Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo. MX2009004551A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020060117929A KR100816065B1 (ko) 2006-11-27 2006-11-27 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐
PCT/KR2007/005892 WO2008066279A1 (en) 2006-11-27 2007-11-21 Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby

Publications (1)

Publication Number Publication Date
MX2009004551A true MX2009004551A (es) 2009-06-15

Family

ID=39411458

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009004551A MX2009004551A (es) 2006-11-27 2007-11-21 Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo.

Country Status (8)

Country Link
US (1) US8541030B2 (es)
EP (1) EP2086669A4 (es)
JP (2) JP2010510206A (es)
KR (1) KR100816065B1 (es)
BR (1) BRPI0715421A2 (es)
CO (1) CO6190545A2 (es)
MX (1) MX2009004551A (es)
WO (1) WO2008066279A1 (es)

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NZ591810A (en) 2008-09-17 2012-12-21 Chiasma Inc Pharmaceutical compositions and related methods of delivery the composition comprises a medium chain fatty acid
KR101663561B1 (ko) * 2009-02-18 2016-10-10 동국제약 주식회사 서방출성 미립구의 제조방법
RU2694901C2 (ru) * 2013-04-18 2019-07-18 Шаньдун Луе Фармасьютикал Ко., Лтд Фармацевтические композиции микросфер гозерелина с пролонгированным высвобождением
JP2016527308A (ja) * 2013-08-06 2016-09-08 ドン クック ファーマシューティカル カンパニー リミテッド エンテカビル微小球及びこれを含む非経口投与用医薬組成物
CN103861537B (zh) * 2014-03-20 2016-01-06 中国热带农业科学院农产品加工研究所 一种精油微胶囊的制备方法
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
CN105223310B (zh) * 2015-10-16 2017-03-01 山东农业大学 一种微胶囊囊芯释放率的测试方法及装置
KR101961848B1 (ko) * 2016-08-25 2019-03-25 영진약품 주식회사 C18:1, c18:1(oh) 또는 c18:2의 장쇄 지방산이 포함된 오일류를 포함한 방출억제제를 적용한 서방출성 마이크로스피어 및 이의 제조방법
KR102113505B1 (ko) * 2018-11-14 2020-05-22 동국제약 주식회사 소마토스타틴 유사체를 함유한 서방형 마이크로스피어의 용출시험법
KR102185348B1 (ko) 2018-12-17 2020-12-01 주식회사 지투지바이오 데슬로렐린을 함유하는 서방형 주사제 및 그 제조방법
JP6810502B1 (ja) * 2020-05-08 2021-01-06 エム・テクニック株式会社 生理活性物質が均一に分散されたマイクロスフェアー及びそれを含有する徐放性製剤
US20210346296A1 (en) * 2020-05-08 2021-11-11 M. Technique Co., Ltd. A biologically active substance uniformly dispersed microsphere and a sustained release formulation comprising the same
US11617720B2 (en) 2020-05-08 2023-04-04 M. Technique Co., Ltd. Main agent uniformly dispersed microsphere and a sustained release formulation comprising the same
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

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Also Published As

Publication number Publication date
JP2012193212A (ja) 2012-10-11
CO6190545A2 (es) 2010-08-19
EP2086669A1 (en) 2009-08-12
JP2010510206A (ja) 2010-04-02
EP2086669A4 (en) 2014-05-28
KR100816065B1 (ko) 2008-03-24
US20100272820A1 (en) 2010-10-28
WO2008066279A1 (en) 2008-06-05
US8541030B2 (en) 2013-09-24
BRPI0715421A2 (pt) 2015-02-03

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