MX2009004551A - Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo. - Google Patents
Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo.Info
- Publication number
- MX2009004551A MX2009004551A MX2009004551A MX2009004551A MX2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A MX 2009004551 A MX2009004551 A MX 2009004551A
- Authority
- MX
- Mexico
- Prior art keywords
- microcapsules
- sustained
- preparation
- initial burst
- good initial
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describe un método para preparar una formulación de liberación sostenida más prolongada que contiene sustancias bioactivas. Más particularmente, la presente invención proporciona un método para preparar microcápsulas de liberación sostenida más prolongada el cual comprende: adicionar una emulsión que incluye sustancias bioactivas, polímero biocompatible y polivinilpirrolidona a una solución acuosa.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020060117929A KR100816065B1 (ko) | 2006-11-27 | 2006-11-27 | 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐 |
PCT/KR2007/005892 WO2008066279A1 (en) | 2006-11-27 | 2007-11-21 | Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009004551A true MX2009004551A (es) | 2009-06-15 |
Family
ID=39411458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009004551A MX2009004551A (es) | 2006-11-27 | 2007-11-21 | Metodo de preparacion de microcapsulas de liberacion sostenida con buena propiedad inhibitoria de aparicion repentina inicial y las microcapsulas del mismo. |
Country Status (8)
Country | Link |
---|---|
US (1) | US8541030B2 (es) |
EP (1) | EP2086669A4 (es) |
JP (2) | JP2010510206A (es) |
KR (1) | KR100816065B1 (es) |
BR (1) | BRPI0715421A2 (es) |
CO (1) | CO6190545A2 (es) |
MX (1) | MX2009004551A (es) |
WO (1) | WO2008066279A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101113044B1 (ko) * | 2008-08-29 | 2012-02-27 | 동국제약 주식회사 | 용매교류증발법에 의한 서방출성 미립구의 제조방법 |
MX2011002836A (es) * | 2008-09-17 | 2011-04-28 | Chiasma Inc | Composiciones farmaceúticas y métodos de administración relacionados. |
KR101663561B1 (ko) * | 2009-02-18 | 2016-10-10 | 동국제약 주식회사 | 서방출성 미립구의 제조방법 |
JP6151848B2 (ja) * | 2013-04-18 | 2017-06-21 | シャンドン ルイ ファーマシューティカル カンパニー リミテッド | ゴセレリン徐放性マイクロスフェア医薬組成物 |
BR112016002342A8 (pt) * | 2013-08-06 | 2018-01-23 | Dong Kook Pharm Co Ltd | microesfera entecavir, método para preparação de uma microesfera entecavir, e, composição farmacêutica |
CN103861537B (zh) * | 2014-03-20 | 2016-01-06 | 中国热带农业科学院农产品加工研究所 | 一种精油微胶囊的制备方法 |
MA41462A (fr) | 2015-02-03 | 2021-05-12 | Chiasma Inc | Méthode de traitement de maladies |
CN105223310B (zh) * | 2015-10-16 | 2017-03-01 | 山东农业大学 | 一种微胶囊囊芯释放率的测试方法及装置 |
KR101961848B1 (ko) * | 2016-08-25 | 2019-03-25 | 영진약품 주식회사 | C18:1, c18:1(oh) 또는 c18:2의 장쇄 지방산이 포함된 오일류를 포함한 방출억제제를 적용한 서방출성 마이크로스피어 및 이의 제조방법 |
KR102113505B1 (ko) * | 2018-11-14 | 2020-05-22 | 동국제약 주식회사 | 소마토스타틴 유사체를 함유한 서방형 마이크로스피어의 용출시험법 |
US20220023217A1 (en) | 2018-12-17 | 2022-01-27 | G2Gbio, Inc. | Sustained-release injection comprising deslorelin, and preparation method therefor |
JP6810502B1 (ja) * | 2020-05-08 | 2021-01-06 | エム・テクニック株式会社 | 生理活性物質が均一に分散されたマイクロスフェアー及びそれを含有する徐放性製剤 |
JP6852943B1 (ja) * | 2020-05-08 | 2021-03-31 | エム・テクニック株式会社 | 主剤が均一に分散されたマイクロスフェアー及びそれを含有する徐放性製剤 |
EP4147720A4 (en) * | 2020-05-08 | 2023-04-26 | M. Technique Co., Ltd. | MICROPHONES WITH A UNIFORMLY DISPERSED BIOACTIVE SUBSTANCE AND PREPARATION WITH DELAYED RELEASE CONTAINING THEM |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU221294B1 (en) * | 1989-07-07 | 2002-09-28 | Novartis Ag | Process for producing retarde compositions containing the active ingredient in a polymeric carrier |
PH30995A (en) * | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
MY107937A (en) | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
DK0474098T3 (da) * | 1990-08-30 | 1994-05-02 | Senju Pharma Co | Middel til kontrolleret lægemiddelfrigivelse |
GB9211268D0 (en) | 1992-05-28 | 1992-07-15 | Ici Plc | Salts of basic peptides with carboxyterminated polyesters |
US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
TW448055B (en) | 1995-09-04 | 2001-08-01 | Takeda Chemical Industries Ltd | Method of production of sustained-release preparation |
EP0765660A3 (en) * | 1995-09-28 | 1998-09-23 | Takeda Chemical Industries, Ltd. | Microcapsules comprising 2-piperazinone-1-acetic acid compounds |
JPH11509862A (ja) | 1996-01-24 | 1999-08-31 | アメリカ合衆国 | 新規「バーストフリー」持続放出型ポリ(ラクチド/グリコリド)微小球 |
JPH10203966A (ja) * | 1996-11-21 | 1998-08-04 | Takeda Chem Ind Ltd | 徐放性マイクロカプセルおよびその製造法 |
US20020039594A1 (en) * | 1997-05-13 | 2002-04-04 | Evan C. Unger | Solid porous matrices and methods of making and using the same |
KR20010002589A (ko) * | 1999-06-16 | 2001-01-15 | 김윤 | 생리활성물질 함유 생분해성 고분자 마이크로스피어의 제조방법 |
AR023940A1 (es) * | 2000-05-03 | 2002-09-04 | Eriochem Sa | Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua |
IT1318539B1 (it) * | 2000-05-26 | 2003-08-27 | Italfarmaco Spa | Composizioni farmaceutiche a rilascio prolungato per lasomministrazione parenterale di sostanze idrofile biologicamente |
JP2005509611A (ja) * | 2001-10-10 | 2005-04-14 | ピエール、ファーブル、メディカマン | 徐放型生物分解性微小球およびその製造方法 |
US20040097419A1 (en) * | 2002-11-19 | 2004-05-20 | Holger Petersen | Organic compounds |
KR100466637B1 (ko) * | 2003-06-26 | 2005-01-13 | 주식회사 펩트론 | 서방성 미립구의 혼합 제형을 연속한 단일 공정으로제조하는 방법 |
ES2741576T3 (es) * | 2003-07-23 | 2020-02-11 | Evonik Corp | Composiciones de liberación controlada |
MY158342A (en) * | 2003-11-14 | 2016-09-30 | Novartis Ag | Pharmaceutical composition |
US7456254B2 (en) | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
ES2527286T3 (es) * | 2004-04-30 | 2015-01-22 | Abraxis Bioscience, Llc | Microesferas de liberación sostenida y métodos de fabricación y uso de las mismas |
US20080066739A1 (en) * | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
US20080311162A1 (en) * | 2007-05-16 | 2008-12-18 | Olivia Darmuzey | Solid form |
-
2006
- 2006-11-27 KR KR1020060117929A patent/KR100816065B1/ko active IP Right Grant
-
2007
- 2007-11-21 WO PCT/KR2007/005892 patent/WO2008066279A1/en active Application Filing
- 2007-11-21 US US12/516,275 patent/US8541030B2/en active Active
- 2007-11-21 EP EP07834198.9A patent/EP2086669A4/en not_active Withdrawn
- 2007-11-21 BR BRPI0715421-6A2A patent/BRPI0715421A2/pt not_active Application Discontinuation
- 2007-11-21 JP JP2009537091A patent/JP2010510206A/ja active Pending
- 2007-11-21 MX MX2009004551A patent/MX2009004551A/es active IP Right Grant
-
2009
- 2009-05-27 CO CO09054432A patent/CO6190545A2/es not_active Application Discontinuation
-
2012
- 2012-07-13 JP JP2012158071A patent/JP2012193212A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BRPI0715421A2 (pt) | 2015-02-03 |
JP2012193212A (ja) | 2012-10-11 |
KR100816065B1 (ko) | 2008-03-24 |
US8541030B2 (en) | 2013-09-24 |
EP2086669A1 (en) | 2009-08-12 |
CO6190545A2 (es) | 2010-08-19 |
JP2010510206A (ja) | 2010-04-02 |
US20100272820A1 (en) | 2010-10-28 |
EP2086669A4 (en) | 2014-05-28 |
WO2008066279A1 (en) | 2008-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |