MX2008012729A - Inhibidores de renina para el tratamiento de hipertension. - Google Patents
Inhibidores de renina para el tratamiento de hipertension.Info
- Publication number
- MX2008012729A MX2008012729A MX2008012729A MX2008012729A MX2008012729A MX 2008012729 A MX2008012729 A MX 2008012729A MX 2008012729 A MX2008012729 A MX 2008012729A MX 2008012729 A MX2008012729 A MX 2008012729A MX 2008012729 A MX2008012729 A MX 2008012729A
- Authority
- MX
- Mexico
- Prior art keywords
- cessation
- hypertension
- renin inhibitor
- administration
- refers
- Prior art date
Links
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- GXGAKHNRMVGRPK-UHFFFAOYSA-N dimagnesium;dioxido-bis[[oxido(oxo)silyl]oxy]silane Chemical compound [Mg+2].[Mg+2].[O-][Si](=O)O[Si]([O-])([O-])O[Si]([O-])=O GXGAKHNRMVGRPK-UHFFFAOYSA-N 0.000 description 1
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- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 150000002314 glycerols Chemical class 0.000 description 1
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- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
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- UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 1
- 235000013980 iron oxide Nutrition 0.000 description 1
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
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- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
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- 239000008194 pharmaceutical composition Substances 0.000 description 1
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- 235000021317 phosphate Nutrition 0.000 description 1
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- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
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- 238000005932 reductive alkylation reaction Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 239000012439 solid excipient Substances 0.000 description 1
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- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
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- 125000001424 substituent group Chemical group 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
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- 150000003573 thiols Chemical class 0.000 description 1
- 230000001732 thrombotic effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 125000003866 trichloromethyl group Chemical group ClC(Cl)(Cl)* 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
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- 229940100445 wheat starch Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78884206P | 2006-04-03 | 2006-04-03 | |
| PCT/US2007/065564 WO2007118023A1 (en) | 2006-04-03 | 2007-03-30 | Renin inhibitors for the treatment of hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008012729A true MX2008012729A (es) | 2008-10-14 |
Family
ID=38420678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008012729A MX2008012729A (es) | 2006-04-03 | 2007-03-30 | Inhibidores de renina para el tratamiento de hipertension. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20090062395A1 (https=) |
| EP (1) | EP2004167A1 (https=) |
| JP (1) | JP2009532494A (https=) |
| KR (1) | KR20080108515A (https=) |
| CN (1) | CN101415413A (https=) |
| AU (1) | AU2007234917B2 (https=) |
| BR (1) | BRPI0710095A2 (https=) |
| CA (1) | CA2645260A1 (https=) |
| CL (1) | CL2007000912A1 (https=) |
| IL (1) | IL193905A0 (https=) |
| MA (1) | MA30387B1 (https=) |
| MX (1) | MX2008012729A (https=) |
| NO (1) | NO20084625L (https=) |
| NZ (1) | NZ571251A (https=) |
| RU (1) | RU2008143055A (https=) |
| SG (1) | SG170830A1 (https=) |
| TN (1) | TNSN08383A1 (https=) |
| TW (1) | TW200806283A (https=) |
| WO (1) | WO2007118023A1 (https=) |
| ZA (1) | ZA200807615B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009087116A1 (en) * | 2008-01-11 | 2009-07-16 | Novartis Ag | Use of spp100 for the treatment of acute mi |
| CN102212012A (zh) * | 2010-04-12 | 2011-10-12 | 上海源力生物技术有限公司 | 一种合成阿利克伦的中间体及其制备方法 |
| WO2013057313A1 (en) | 2011-10-20 | 2013-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the detection and the treatment of cardiac remodeling |
| CA3137138A1 (en) * | 2019-04-18 | 2020-10-22 | EyePoint Pharmaceuticals, Inc. | Methods of treating hypertension with activators of tie-2 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5659065A (en) * | 1994-04-18 | 1997-08-19 | Novartis Corporation | Alpha-aminoalkanoic acids and reduction products |
| MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| US5606078A (en) * | 1994-04-18 | 1997-02-25 | Ciba-Geigy Corporation | 3,5-Disubstituted tetrahydrofuran-2-ones |
| CA2490811A1 (en) * | 2002-06-28 | 2004-01-08 | Novartis Ag | Use of organic compounds |
| WO2004100871A2 (en) * | 2003-05-09 | 2004-11-25 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and a renin inhibitor |
| US20050209141A1 (en) * | 2003-10-17 | 2005-09-22 | Silver Randi B | Mast cell-derived renin |
| PE20142101A1 (es) * | 2004-03-17 | 2014-12-27 | Novartis Ag | Composiciones farmaceuticas de aliskiren |
| CA2581927C (en) * | 2004-09-27 | 2013-04-09 | Pantarhei Bioscience B.V. | Treatment or prevention of unscheduled bleeding in women on progestogen containing medication |
-
2007
- 2007-03-30 AU AU2007234917A patent/AU2007234917B2/en not_active Ceased
- 2007-03-30 JP JP2009504386A patent/JP2009532494A/ja active Pending
- 2007-03-30 MX MX2008012729A patent/MX2008012729A/es not_active Application Discontinuation
- 2007-03-30 WO PCT/US2007/065564 patent/WO2007118023A1/en not_active Ceased
- 2007-03-30 RU RU2008143055/14A patent/RU2008143055A/ru unknown
- 2007-03-30 EP EP07759755A patent/EP2004167A1/en not_active Withdrawn
- 2007-03-30 KR KR1020087024219A patent/KR20080108515A/ko not_active Withdrawn
- 2007-03-30 CA CA002645260A patent/CA2645260A1/en not_active Abandoned
- 2007-03-30 BR BRPI0710095-7A patent/BRPI0710095A2/pt not_active IP Right Cessation
- 2007-03-30 NZ NZ571251A patent/NZ571251A/en not_active IP Right Cessation
- 2007-03-30 CN CNA2007800124642A patent/CN101415413A/zh active Pending
- 2007-03-30 SG SG201102387-6A patent/SG170830A1/en unknown
- 2007-03-30 US US12/293,107 patent/US20090062395A1/en not_active Abandoned
- 2007-04-02 TW TW096111640A patent/TW200806283A/zh unknown
- 2007-04-02 CL CL200700912A patent/CL2007000912A1/es unknown
-
2008
- 2008-09-04 ZA ZA200807615A patent/ZA200807615B/xx unknown
- 2008-09-04 IL IL193905A patent/IL193905A0/en unknown
- 2008-09-26 TN TNP2008000383A patent/TNSN08383A1/en unknown
- 2008-10-23 MA MA31327A patent/MA30387B1/fr unknown
- 2008-11-03 NO NO20084625A patent/NO20084625L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0710095A2 (pt) | 2011-08-02 |
| JP2009532494A (ja) | 2009-09-10 |
| TNSN08383A1 (en) | 2009-12-29 |
| CN101415413A (zh) | 2009-04-22 |
| TW200806283A (en) | 2008-02-01 |
| AU2007234917A1 (en) | 2007-10-18 |
| AU2007234917B2 (en) | 2011-05-12 |
| MA30387B1 (fr) | 2009-05-04 |
| NO20084625L (no) | 2008-11-03 |
| IL193905A0 (en) | 2009-08-03 |
| CA2645260A1 (en) | 2007-10-18 |
| CL2007000912A1 (es) | 2008-03-14 |
| NZ571251A (en) | 2011-12-22 |
| SG170830A1 (en) | 2011-05-30 |
| KR20080108515A (ko) | 2008-12-15 |
| US20090062395A1 (en) | 2009-03-05 |
| ZA200807615B (en) | 2009-10-28 |
| WO2007118023A1 (en) | 2007-10-18 |
| EP2004167A1 (en) | 2008-12-24 |
| RU2008143055A (ru) | 2010-05-10 |
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