MX2008001794A - Proceso para la sintesis de mandipropamida y derivados de la misma. - Google Patents

Proceso para la sintesis de mandipropamida y derivados de la misma.

Info

Publication number
MX2008001794A
MX2008001794A MX2008001794A MX2008001794A MX2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A MX 2008001794 A MX2008001794 A MX 2008001794A
Authority
MX
Mexico
Prior art keywords
carbon atoms
sup
sub
compound
formula
Prior art date
Application number
MX2008001794A
Other languages
English (en)
Inventor
Beat Jau
Gottfried Seifert
Martin Zeller
Martin Charles Bowden
Dominik Faber
Thomas Aitcheson Clark
Fanny Delphine Brigtte Giordano
Hans-Dieter Schneider
Juerg Wiss
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35098316&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2008001794(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2008001794A publication Critical patent/MX2008001794A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/10Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/16Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/37Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/46Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un proceso para la preparacion de un compuesto de la formula (I) en donde: R es un grupo alquinilo; R1 es alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquil-alquil, fenilo y fenilalquilo, esto es posible a su vez para que todos los grupos anteriores lleven uno o mas atomos de halogeno identicos o diferentes; alcoxi; alqueniloxi; alquiniloxi; alcoxialquilo; haloalcoxi; alquiltio; haloalquiltio; alquilsulfonilo; formilo; alcanoilo; hidroxi; halogeno; ciano; nitro; amino; alquilamino; dialquilamino; carboxilo; alcoxicarbonilo; alqueniloxicarbonilo; o alquiniloxicarbonilo; y n es un entero de 0 a 3, el proceso comprende (i) la reaccion de un compuesto de la formula (III) en donde R, R1 y n son de conformidad con lo definido aqui anteriormente; m y m' son independientemente 0 o 1; cuando m y m' son ambos 0, A es un grupo alquilo, alquenilo o alquinilo (que tiene convenientemente hasta ocho atomos de carbono), opcionalmente substituido por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; cuando uno de m y m' es 0 y el otro es 1, A es un grupo alcanodiilo, alquenodiilo o alquinodiilo que contiene por lo menos dos atomos de carbono (y que tiene convenientemente hasta ocho atomos de carbono), opcionalmente substituidos por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; cuando m y el m' son ambos 1, A es un alcanotriilo, alquenotriilo o un grupo alquinotriilo que contiene por lo menos tres atomos de carbono (y que tiene convenientemente hasta ocho atomos de carbono), substituidos opcionalmente por uno o mas grupos seleccionados independientemente de halogeno, hidroxi, alcoxi, dialquilamino C1-4 o ciano; y en donde si el grupo A contiene tres o mas atomos de carbono, uno o mas de los atomos de carbono cada uno opcionalmente puede ser substituido por un atomo de oxigeno, siempre que hay por lo menos un atomo de carbono entre cualquiera de los dos atomos de oxigeno en la molecula, con un compuesto de la formula (IV) para dar un compuesto de formula (II) en donde R, R1 y n son de conformidad con lo definido aqui anteriormente, y (ii) la reaccion de un compuesto de la formula (II) con (ver formula), en donde L es un grupo de salida, para dar el compuesto de la formula (I) de conformidad con lo definido aqui anteriormente.
MX2008001794A 2005-08-15 2006-08-08 Proceso para la sintesis de mandipropamida y derivados de la misma. MX2008001794A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0516705.1A GB0516705D0 (en) 2005-08-15 2005-08-15 Process
PCT/GB2006/002946 WO2007020381A2 (en) 2005-08-15 2006-08-08 Process for the synthesis of mandipropamid and derivatives thereof

Publications (1)

Publication Number Publication Date
MX2008001794A true MX2008001794A (es) 2008-04-07

Family

ID=35098316

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001794A MX2008001794A (es) 2005-08-15 2006-08-08 Proceso para la sintesis de mandipropamida y derivados de la misma.

Country Status (26)

Country Link
US (1) US8129560B2 (es)
EP (1) EP1919857B1 (es)
JP (1) JP5350790B2 (es)
KR (1) KR101305928B1 (es)
CN (1) CN101243040B (es)
AR (2) AR057741A1 (es)
AU (1) AU2006281293B2 (es)
BR (1) BRPI0616593B1 (es)
CA (1) CA2619435C (es)
CR (1) CR9710A (es)
EC (1) ECSP088183A (es)
ES (1) ES2572137T3 (es)
GB (1) GB0516705D0 (es)
GT (1) GT200600369A (es)
HN (1) HN2006029142A (es)
HU (1) HUE028929T2 (es)
IL (3) IL188919A (es)
MX (1) MX2008001794A (es)
MY (1) MY150654A (es)
NZ (1) NZ574781A (es)
PL (1) PL1919857T3 (es)
RU (1) RU2470914C9 (es)
TW (2) TWI399363B (es)
UA (1) UA90810C2 (es)
WO (1) WO2007020381A2 (es)
ZA (1) ZA200800691B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0808764D0 (en) * 2008-05-14 2008-06-18 Syngenta Ltd Process
JP5747625B2 (ja) 2011-04-12 2015-07-15 住友化学株式会社 マンデロニトリル化合物の製造方法
WO2013113773A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113778A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113776A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113716A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113788A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113720A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
AR089884A1 (es) 2012-02-03 2014-09-24 Basf Se Compuestos fungicidas de pirimidina
EP2809659A1 (en) 2012-02-03 2014-12-10 Basf Se Fungicidal pyrimidine compounds
CN110204556B (zh) * 2019-07-16 2020-09-18 重庆医药高等专科学校 (rs)-甲氧基头孢西丁的制备方法
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors
WO2024126744A1 (en) 2022-12-16 2024-06-20 Syngenta Crop Protection Ag Improved pesticidal compositions

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GB1030756A (en) * 1963-04-01 1966-05-25 Boots Pure Drug Co Ltd Anti-inflammatory compositions comprising biphenylyl-alkane derivatives
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
DK133742B (da) 1970-10-30 1976-07-12 Merck & Co Inc Fremgangsmåde til fremstilling af 2-acetamidoethyl-(3-trifluormethylphenoxy)-(4-chlorphenyl)-acetat.
FR2131802A7 (en) * 1971-03-11 1972-11-17 Micsunescu Francine Galvanizing bath brigenting agents - produced by reacting aromatic aldehydes or ketones with acetylenic alcohols
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GT199800109A (es) * 1997-08-06 2000-01-13 Derivados de n-sulfonilglicinalquiniloxifenetilamida microbicidas.
GB9804265D0 (en) * 1998-02-27 1998-04-22 Ciba Geigy Ag Organic compounds
TW564244B (en) * 1999-01-11 2003-12-01 Novartis Ag Novel propargylether derivatives
GB0011944D0 (en) * 2000-05-17 2000-07-05 Novartis Ag Organic compounds
GB0108339D0 (en) * 2001-04-03 2001-05-23 Syngenta Participations Ag Organics compounds
GB0127559D0 (en) * 2001-11-16 2002-01-09 Syngenta Participations Ag Organic compounds
GB0127554D0 (en) * 2001-11-16 2002-01-09 Syngenta Participations Ag Organic compounds
WO2004016594A1 (ja) * 2002-08-19 2004-02-26 Sumitomo Chemical Company, Limited フェニルピリジン化合物およびこれを含有する殺菌組成物
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Also Published As

Publication number Publication date
GB0516705D0 (en) 2005-09-21
AR057741A1 (es) 2007-12-12
CA2619435C (en) 2014-02-18
AU2006281293B2 (en) 2011-04-28
KR20080034934A (ko) 2008-04-22
RU2470914C2 (ru) 2012-12-27
CN101243040B (zh) 2012-12-05
IL226404A0 (en) 2013-06-27
IL226403A0 (en) 2013-06-27
US8129560B2 (en) 2012-03-06
RU2008110063A (ru) 2009-09-27
ZA200800691B (en) 2011-12-28
AU2006281293A1 (en) 2007-02-22
AR080271A2 (es) 2012-03-28
MY150654A (en) 2014-02-14
RU2470914C9 (ru) 2016-05-20
WO2007020381A2 (en) 2007-02-22
EP1919857B1 (en) 2016-03-09
US20090118532A1 (en) 2009-05-07
ES2572137T3 (es) 2016-05-30
HUE028929T2 (en) 2017-01-30
ECSP088183A (es) 2008-03-26
WO2007020381A3 (en) 2007-05-03
TW201332944A (zh) 2013-08-16
IL188919A (en) 2015-04-30
NZ574781A (en) 2011-06-30
JP2009504715A (ja) 2009-02-05
TW200720230A (en) 2007-06-01
JP5350790B2 (ja) 2013-11-27
CA2619435A1 (en) 2007-02-22
IL188919A0 (en) 2008-08-07
TWI428314B (zh) 2014-03-01
CN101243040A (zh) 2008-08-13
KR101305928B1 (ko) 2013-09-12
PL1919857T3 (pl) 2016-10-31
TWI399363B (zh) 2013-06-21
CR9710A (es) 2008-04-16
HN2006029142A (es) 2010-08-19
BRPI0616593A2 (pt) 2011-06-28
UA90810C2 (ru) 2010-05-25
BRPI0616593B1 (pt) 2017-06-27
GT200600369A (es) 2007-09-19
EP1919857A2 (en) 2008-05-14

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