MX2008001746A - Composiciones de emulsion de propofol intravenosas que tienen eficacia de conservacion. - Google Patents
Composiciones de emulsion de propofol intravenosas que tienen eficacia de conservacion.Info
- Publication number
- MX2008001746A MX2008001746A MX2008001746A MX2008001746A MX2008001746A MX 2008001746 A MX2008001746 A MX 2008001746A MX 2008001746 A MX2008001746 A MX 2008001746A MX 2008001746 A MX2008001746 A MX 2008001746A MX 2008001746 A MX2008001746 A MX 2008001746A
- Authority
- MX
- Mexico
- Prior art keywords
- emulsion compositions
- preservative efficacy
- intravenous propofol
- monoglyceryl ester
- propofol emulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invencion revela una composicion en emulsion aceite en agua de propofol intravenosa estable que tiene conservadores mezclados de baja toxicidad que es capaz de soportar contaminacion accidental de bacterias y hongos. El sistema de conservador empleado comprende ester de monoglicerilo de acido laurico (monolaurina) y un miembro seleccionado de (a) acido caprico y/o sus sales alcalinas solubles o su ester de monoglicerilo (monocaprina); (b) edetato y (c) acido capricho y/o sus sales alcalinas solubles o su ester de monoglicerilo (monocaprina) y edetato.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN906MU2005 | 2005-08-05 | ||
PCT/IN2006/000281 WO2007052288A2 (en) | 2005-08-05 | 2006-08-04 | Intravenous propofol emulsion compositions having preservative efficacy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008001746A true MX2008001746A (es) | 2008-04-07 |
Family
ID=38006301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008001746A MX2008001746A (es) | 2005-08-05 | 2006-08-04 | Composiciones de emulsion de propofol intravenosas que tienen eficacia de conservacion. |
Country Status (16)
Country | Link |
---|---|
US (1) | US8759404B2 (es) |
EP (1) | EP1922060B1 (es) |
JP (1) | JP2009503059A (es) |
KR (1) | KR20080043793A (es) |
CN (1) | CN101304728A (es) |
AT (1) | ATE420625T1 (es) |
AU (1) | AU2006310113A1 (es) |
BR (1) | BRPI0614084A2 (es) |
CA (1) | CA2618026A1 (es) |
DE (1) | DE602006004887D1 (es) |
EA (1) | EA200800258A1 (es) |
ES (1) | ES2318802T3 (es) |
IL (1) | IL189310A0 (es) |
MX (1) | MX2008001746A (es) |
WO (1) | WO2007052288A2 (es) |
ZA (1) | ZA200801227B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080262084A1 (en) * | 2004-09-13 | 2008-10-23 | Gautam Vinod Daftary | Stable Emulsion Compositions for Intravenous Administration Having Preservatie Efficacy |
WO2008023384A1 (en) * | 2006-08-24 | 2008-02-28 | Bharat Serums & Vaccines Ltd. | Propofol emulsion compositions for intravenous administration |
BRPI0604377A (pt) * | 2006-10-27 | 2008-06-24 | Cristalia Prod Quimicos Farm | microemulsão óleo/água de propofol estável e pronta-para-uso |
JP2010163397A (ja) * | 2009-01-16 | 2010-07-29 | Japan Ecologia Co Ltd | 抗菌性組成物 |
CN102869345B (zh) | 2010-03-17 | 2015-02-11 | 诺瓦利克有限责任公司 | 用于治疗眼内压增高的药物组合物 |
KR101805087B1 (ko) * | 2010-09-16 | 2017-12-05 | 주식회사 엘지화학 | 높은 방부력을 제공하는 오일 주사 제형 |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
PT2661280T (pt) | 2011-01-04 | 2019-02-25 | Novaliq Gmbh | Emulsões o/a compreendendo alcanos semifluorados |
WO2012160180A2 (en) | 2011-05-25 | 2012-11-29 | Novaliq Gmbh | Pharmaceutical composition for administration to nails |
PL2714010T3 (pl) | 2011-05-25 | 2017-08-31 | Novaliq Gmbh | Kompozycja farmaceutyczna do miejscowego stosowania oparta na semifluorowanych alkanach |
AU2013211645B2 (en) | 2012-01-23 | 2017-06-15 | Novaliq Gmbh | Stabilised protein compositions based on semifluorinated alkanes |
CN102525921B (zh) | 2012-02-06 | 2013-08-07 | 西安力邦制药有限公司 | 2,2’,6,6’-四异丙基-4,4’-二联苯酚脂微球制剂及其制备方法 |
AU2013249086A1 (en) * | 2012-04-20 | 2014-10-30 | Hennepin Life Sciences | Compositions for topical treatment of microbial infections |
WO2014033751A2 (en) * | 2012-08-16 | 2014-03-06 | Emcure Pharmaceuticals Limited | Pharmaceutical composition of propofol |
EP3181119B1 (en) | 2012-09-12 | 2019-07-10 | Novaliq GmbH | Semifluorinated alkane compositions for use in the treatment of keratoconjunctivitis sicca |
EP2895158B1 (en) | 2012-09-12 | 2019-11-20 | Novaliq GmbH | Compositions comprising mixtures of semifluorinated alkanes |
JP6503349B2 (ja) | 2013-07-23 | 2019-04-17 | ノバリック ゲーエムベーハー | 安定化された抗体組成物 |
WO2017001549A1 (en) * | 2015-07-01 | 2017-01-05 | Fresenius Kabi Deutschland Gmbh | Propofol emulsion for parenteral administration |
PT3355990T (pt) | 2015-09-30 | 2019-09-11 | Novaliq Gmbh | Compostos semifluorados e as suas composições |
DE202016008739U1 (de) | 2015-09-30 | 2019-04-29 | Novaliq Gmbh | Semifluorierte Verbindungen |
KR102257916B1 (ko) | 2016-06-23 | 2021-05-28 | 노바리크 게엠베하 | 드롭 디스펜서를 포함하는 키트 |
CN109890374A (zh) | 2016-09-22 | 2019-06-14 | 诺瓦利克有限责任公司 | 用于治疗睑缘炎的药物组合物 |
JP6869336B2 (ja) | 2016-09-23 | 2021-05-12 | ノバリック ゲーエムベーハー | シクロスポリンを含む眼科用組成物 |
WO2018193093A1 (en) | 2017-04-21 | 2018-10-25 | Novaliq Gmbh | Iodine compositions |
CN110650734A (zh) | 2017-05-12 | 2020-01-03 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
CN111372566A (zh) | 2017-09-27 | 2020-07-03 | 诺瓦利克有限责任公司 | 用于治疗眼部疾病的包含拉坦前列素的眼科用组合物 |
US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
US20200316043A1 (en) * | 2017-12-20 | 2020-10-08 | Aurobindo Pharma Ltd. | Pharmaceutical composition comprising clevidipine and process for preparation thereof |
WO2019166631A1 (en) | 2018-03-02 | 2019-09-06 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
CN112823020A (zh) | 2018-10-12 | 2021-05-18 | 诺瓦利克有限责任公司 | 用于治疗干眼病的眼用组合物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4067997A (en) * | 1975-05-21 | 1978-01-10 | Med-Chem Laboratories | Synergistic microbecidal composition and method |
GB9405593D0 (en) * | 1994-03-22 | 1994-05-11 | Zeneca Ltd | Pharmaceutical compositions |
DE69936911T2 (de) * | 1998-02-10 | 2008-05-15 | Sicor Inc., Irvine | Propofolhaltiges arzneimittel enthaltend sulfite |
US6028108A (en) * | 1998-10-22 | 2000-02-22 | America Home Products Corporation | Propofol composition comprising pentetate |
US6140373A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6140374A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6100302A (en) | 1999-04-05 | 2000-08-08 | Baxter International Inc. | Propofol formulation with enhanced microbial characteristics |
SE0001865D0 (sv) * | 2000-05-19 | 2000-05-19 | Astrazeneca Ab | Management of septic shock |
GB0012597D0 (en) * | 2000-05-25 | 2000-07-12 | Astrazeneca Ab | Formulation |
IL153457A0 (en) * | 2000-06-16 | 2003-07-06 | Skyepharma Canada Inc | Improved injectable dispersions of propofol |
WO2002043765A2 (en) * | 2000-11-28 | 2002-06-06 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
US7034013B2 (en) * | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
-
2006
- 2006-08-04 JP JP2008524681A patent/JP2009503059A/ja active Pending
- 2006-08-04 AT AT06842710T patent/ATE420625T1/de not_active IP Right Cessation
- 2006-08-04 EP EP06842710A patent/EP1922060B1/en not_active Not-in-force
- 2006-08-04 DE DE602006004887T patent/DE602006004887D1/de active Active
- 2006-08-04 WO PCT/IN2006/000281 patent/WO2007052288A2/en active Application Filing
- 2006-08-04 KR KR1020087004739A patent/KR20080043793A/ko not_active Application Discontinuation
- 2006-08-04 CN CNA2006800367264A patent/CN101304728A/zh active Pending
- 2006-08-04 AU AU2006310113A patent/AU2006310113A1/en not_active Abandoned
- 2006-08-04 MX MX2008001746A patent/MX2008001746A/es not_active Application Discontinuation
- 2006-08-04 EA EA200800258A patent/EA200800258A1/ru unknown
- 2006-08-04 ES ES06842710T patent/ES2318802T3/es active Active
- 2006-08-04 BR BRPI0614084-0A patent/BRPI0614084A2/pt not_active Application Discontinuation
- 2006-08-04 CA CA002618026A patent/CA2618026A1/en not_active Abandoned
-
2007
- 2007-03-02 US US11/714,061 patent/US8759404B2/en active Active
-
2008
- 2008-02-05 ZA ZA200801227A patent/ZA200801227B/xx unknown
- 2008-02-05 IL IL189310A patent/IL189310A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007052288A2 (en) | 2007-05-10 |
ATE420625T1 (de) | 2009-01-15 |
CN101304728A (zh) | 2008-11-12 |
CA2618026A1 (en) | 2007-05-10 |
KR20080043793A (ko) | 2008-05-19 |
AU2006310113A1 (en) | 2007-05-10 |
IL189310A0 (en) | 2008-06-05 |
ES2318802T3 (es) | 2009-05-01 |
EA200800258A1 (ru) | 2008-06-30 |
US20070249730A1 (en) | 2007-10-25 |
WO2007052288A3 (en) | 2007-08-30 |
EP1922060B1 (en) | 2009-01-14 |
DE602006004887D1 (de) | 2009-03-05 |
ZA200801227B (en) | 2008-12-31 |
BRPI0614084A2 (pt) | 2011-03-09 |
US8759404B2 (en) | 2014-06-24 |
EP1922060A2 (en) | 2008-05-21 |
JP2009503059A (ja) | 2009-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |