MX2007015988A - Derivados de benzofuranilo como inhibidores del receptor 5-ht6. - Google Patents
Derivados de benzofuranilo como inhibidores del receptor 5-ht6.Info
- Publication number
- MX2007015988A MX2007015988A MX2007015988A MX2007015988A MX2007015988A MX 2007015988 A MX2007015988 A MX 2007015988A MX 2007015988 A MX2007015988 A MX 2007015988A MX 2007015988 A MX2007015988 A MX 2007015988A MX 2007015988 A MX2007015988 A MX 2007015988A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- receptor
- body weight
- disorders
- compound according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0501383 | 2005-06-17 | ||
| US70652305P | 2005-08-09 | 2005-08-09 | |
| PCT/EP2006/063249 WO2006134150A1 (en) | 2005-06-17 | 2006-06-15 | Benzofuranyl derivatives as 5-ht6-receptor inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007015988A true MX2007015988A (es) | 2008-03-07 |
Family
ID=36659956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007015988A MX2007015988A (es) | 2005-06-17 | 2006-06-15 | Derivados de benzofuranilo como inhibidores del receptor 5-ht6. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7582767B2 (https=) |
| EP (1) | EP1896460B1 (https=) |
| JP (1) | JP2008543813A (https=) |
| KR (1) | KR20080017482A (https=) |
| CN (1) | CN101193885B (https=) |
| AU (1) | AU2006259082B2 (https=) |
| BR (1) | BRPI0612746A2 (https=) |
| CA (1) | CA2610383A1 (https=) |
| DE (1) | DE602006008002D1 (https=) |
| DK (1) | DK1896460T3 (https=) |
| EA (1) | EA015671B1 (https=) |
| ES (1) | ES2330145T3 (https=) |
| IL (1) | IL187575A (https=) |
| MX (1) | MX2007015988A (https=) |
| NO (1) | NO20080354L (https=) |
| NZ (1) | NZ563510A (https=) |
| WO (1) | WO2006134150A1 (https=) |
| ZA (1) | ZA200710468B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0303480D0 (sv) * | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
| WO2014013014A1 (en) | 2012-07-18 | 2014-01-23 | Fundació Privada Centre De Regulació Genòmica (Crg) | Jak inhibitors for activation of epidermal stem cell populations |
| CN103880797B (zh) * | 2014-03-26 | 2015-12-02 | 沈阳大学 | 苯并呋喃类化合物及其医药用途 |
| WO2018041989A1 (en) | 2016-09-02 | 2018-03-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating refractory celiac disease type 2 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| EP3947737A2 (en) | 2019-04-02 | 2022-02-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| EP3955920A1 (en) | 2019-04-16 | 2022-02-23 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of jak inhibitors for the treatment of painful conditions involving nav1.7 channels |
| WO2023222565A1 (en) | 2022-05-16 | 2023-11-23 | Institut National de la Santé et de la Recherche Médicale | Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| CA2353962C (en) | 1998-12-11 | 2009-09-29 | Virginia Commonwealth University | Selective 5-ht6 receptor ligands |
| CN1800185A (zh) | 2001-06-11 | 2006-07-12 | 比奥维特罗姆股份公司 | 取代的磺酰胺化合物、其制备方法及其作为治疗cns疾病、肥胖和ii型糖尿病的药物的应用 |
| RS44204A (sr) * | 2001-11-22 | 2007-06-04 | Biovitrum Ab., | Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1 |
| WO2004000828A1 (en) | 2002-06-20 | 2003-12-31 | Biovitrum Ab | New compounds useful for the treatment of obesity, type ii diabetes and cns disorders |
| JP4754821B2 (ja) * | 2002-06-20 | 2011-08-24 | プロキシマゲン・リミテッド | 肥満症、ｉｉ型糖尿病およびｃｎｓ障害の治療に有用な新規化合物 |
| SE0303480D0 (sv) * | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
-
2006
- 2006-06-05 US US11/447,524 patent/US7582767B2/en not_active Expired - Fee Related
- 2006-06-15 ES ES06763743T patent/ES2330145T3/es active Active
- 2006-06-15 EA EA200800071A patent/EA015671B1/ru not_active IP Right Cessation
- 2006-06-15 WO PCT/EP2006/063249 patent/WO2006134150A1/en not_active Ceased
- 2006-06-15 CA CA002610383A patent/CA2610383A1/en not_active Abandoned
- 2006-06-15 JP JP2008516325A patent/JP2008543813A/ja not_active Withdrawn
- 2006-06-15 DK DK06763743T patent/DK1896460T3/da active
- 2006-06-15 ZA ZA200710468A patent/ZA200710468B/xx unknown
- 2006-06-15 KR KR1020087001242A patent/KR20080017482A/ko not_active Ceased
- 2006-06-15 CN CN2006800201432A patent/CN101193885B/zh not_active Expired - Fee Related
- 2006-06-15 AU AU2006259082A patent/AU2006259082B2/en not_active Ceased
- 2006-06-15 EP EP06763743A patent/EP1896460B1/en not_active Not-in-force
- 2006-06-15 DE DE602006008002T patent/DE602006008002D1/de active Active
- 2006-06-15 BR BRPI0612746-0A patent/BRPI0612746A2/pt not_active IP Right Cessation
- 2006-06-15 MX MX2007015988A patent/MX2007015988A/es active IP Right Grant
- 2006-06-15 NZ NZ563510A patent/NZ563510A/en not_active IP Right Cessation
-
2007
- 2007-11-22 IL IL187575A patent/IL187575A/en not_active IP Right Cessation
-
2008
- 2008-01-17 NO NO20080354A patent/NO20080354L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1896460A1 (en) | 2008-03-12 |
| WO2006134150A1 (en) | 2006-12-21 |
| DE602006008002D1 (de) | 2009-09-03 |
| IL187575A0 (en) | 2008-03-20 |
| JP2008543813A (ja) | 2008-12-04 |
| US20060293361A1 (en) | 2006-12-28 |
| US7582767B2 (en) | 2009-09-01 |
| CN101193885A (zh) | 2008-06-04 |
| AU2006259082A1 (en) | 2006-12-21 |
| AU2006259082B2 (en) | 2011-07-14 |
| NZ563510A (en) | 2011-01-28 |
| BRPI0612746A2 (pt) | 2010-11-30 |
| ES2330145T3 (es) | 2009-12-04 |
| EA015671B1 (ru) | 2011-10-31 |
| IL187575A (en) | 2012-12-31 |
| EP1896460B1 (en) | 2009-07-22 |
| CN101193885B (zh) | 2011-07-27 |
| ZA200710468B (en) | 2009-04-29 |
| CA2610383A1 (en) | 2006-12-21 |
| HK1112918A1 (en) | 2008-09-19 |
| KR20080017482A (ko) | 2008-02-26 |
| DK1896460T3 (da) | 2009-11-16 |
| EA200800071A1 (ru) | 2008-10-30 |
| NO20080354L (no) | 2008-01-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Audinot et al. | New selective ligands of human cloned melatonin MT1 and MT2 receptors | |
| RU2449990C2 (ru) | Индолы в качестве модуляторов 5-ht6 | |
| CA2540861A1 (en) | Novel tetraydrospiro{piperidine-2,7' -pyrrolo[3,2-b]pyridine derivatives and novel indole derivatives useful in the treatment of 5-ht6 receptor -related disorders | |
| US20060142269A1 (en) | New compounds | |
| Seggel et al. | A structure-affinity study of the binding of 4-substituted analogs of 1-(2, 5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin receptors | |
| JPH08325257A (ja) | 新規なピペラジン、ピペリジン及び１，２，５，６−テトラヒドロピリジン化合物、これらの製造方法及びこれらを含む医薬組成物 | |
| JP2004516239A (ja) | メラニン凝集ホルモン受容体リガンド | |
| TWI237023B (en) | Benzoxazinone derivatives, their preparation and use | |
| RU2191776C2 (ru) | Эрголиновые производные, способ их получения, фармацевтическая композиция | |
| JP2007502272A (ja) | ５‐ＨＴ２Ｃ受容体アゴニストとしての６‐（２，２，２‐トリフルオロエチルアミノ）‐７‐クロロ‐２，３，４，５‐テトラヒドロ‐１Ｈ‐ベンゾ［ｄ］アゼピン | |
| NO180486B (no) | Nye indolforbindelser og anvendelse av disse i farmasöytiske preparater | |
| MX2007015988A (es) | Derivados de benzofuranilo como inhibidores del receptor 5-ht6. | |
| WO2023046150A1 (zh) | 磺酰胺类化合物及其制备方法和用途 | |
| US20080176829A1 (en) | Compounds | |
| Schlachter et al. | Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor | |
| JPH037257A (ja) | ピリジン誘導体及びそれを有効成分とする向精神剤 | |
| Magli et al. | Synthesis, docking studies, and pharmacological evaluation of 5HT2C ligands containing the N′‐cyanoisonicotinamidine or N′‐cyanopicolinamidine nucleus | |
| TW568786B (en) | A combination, pharmaceutical formulation, and kit for use in the treatment of affective disorders | |
| HK1112918B (en) | Benzofuranyl derivatives as 5-ht6-receptor inhibitors | |
| WO2006062481A1 (en) | New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders . | |
| Banerjee et al. | Synthesis and Biological Studies of a Novel CB1 Antagonist | |
| TW460472B (en) | Process for preparing cyclic thioamides | |
| Stjernlöf et al. | 5-, 6-, 7-and 8-amino-2-(N, N-di-n-propylamino)-1, 2, 3, 4-tetrahydronaphthalenes: centrally acting DA and 5-HT1A agonists | |
| JP2008533085A (ja) | ５ｈｔ５ａレセプターアンタゴニストとしての２−アニリノ−３，４−ジヒドロ−キナゾリンの使用 | |
| Schuellner et al. | Synthesis and Biological Evaluation of 14‐Alkoxymorphinans. Part 19: Effect of 14‐O‐Benzylation on the Opioid Receptor Affinity and Antagonist Potency of Naltrexone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |