DK1896460T3 - Benzofuranylderivater som 5-HT6-receptorinhibitorer - Google Patents
Benzofuranylderivater som 5-HT6-receptorinhibitorerInfo
- Publication number
- DK1896460T3 DK1896460T3 DK06763743T DK06763743T DK1896460T3 DK 1896460 T3 DK1896460 T3 DK 1896460T3 DK 06763743 T DK06763743 T DK 06763743T DK 06763743 T DK06763743 T DK 06763743T DK 1896460 T3 DK1896460 T3 DK 1896460T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor inhibitors
- benzofuranyl derivatives
- benzofuranyl
- derivatives
- inhibitors
- Prior art date
Links
- 108091005435 5-HT6 receptors Proteins 0.000 title 1
- 125000000499 benzofuranyl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0501383 | 2005-06-17 | ||
| US70652305P | 2005-08-09 | 2005-08-09 | |
| PCT/EP2006/063249 WO2006134150A1 (en) | 2005-06-17 | 2006-06-15 | Benzofuranyl derivatives as 5-ht6-receptor inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1896460T3 true DK1896460T3 (da) | 2009-11-16 |
Family
ID=36659956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06763743T DK1896460T3 (da) | 2005-06-17 | 2006-06-15 | Benzofuranylderivater som 5-HT6-receptorinhibitorer |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7582767B2 (da) |
| EP (1) | EP1896460B1 (da) |
| JP (1) | JP2008543813A (da) |
| KR (1) | KR20080017482A (da) |
| CN (1) | CN101193885B (da) |
| AU (1) | AU2006259082B2 (da) |
| BR (1) | BRPI0612746A2 (da) |
| CA (1) | CA2610383A1 (da) |
| DE (1) | DE602006008002D1 (da) |
| DK (1) | DK1896460T3 (da) |
| EA (1) | EA015671B1 (da) |
| ES (1) | ES2330145T3 (da) |
| HK (1) | HK1112918A1 (da) |
| IL (1) | IL187575A (da) |
| MX (1) | MX2007015988A (da) |
| NO (1) | NO20080354L (da) |
| NZ (1) | NZ563510A (da) |
| WO (1) | WO2006134150A1 (da) |
| ZA (1) | ZA200710468B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0303480D0 (sv) * | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
| WO2014013014A1 (en) | 2012-07-18 | 2014-01-23 | Fundació Privada Centre De Regulació Genòmica (Crg) | Jak inhibitors for activation of epidermal stem cell populations |
| CN103880797B (zh) * | 2014-03-26 | 2015-12-02 | 沈阳大学 | 苯并呋喃类化合物及其医药用途 |
| WO2018041989A1 (en) | 2016-09-02 | 2018-03-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating refractory celiac disease type 2 |
| US20220177978A1 (en) | 2019-04-02 | 2022-06-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| EP3955920A1 (en) | 2019-04-16 | 2022-02-23 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Use of jak inhibitors for the treatment of painful conditions involving nav1.7 channels |
| WO2023222565A1 (en) | 2022-05-16 | 2023-11-23 | Institut National de la Santé et de la Recherche Médicale | Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| DE69930308T2 (de) | 1998-12-11 | 2006-11-30 | Virginia Commonwealth University | Selektive 5-ht 6-rezeptor-liganden |
| IL158590A0 (en) | 2001-06-11 | 2004-05-12 | Biovitrum Ab | Substituted sulfonamide compounds, process for their use as medicament for the treatment of cns disorders, obesity and type ii diabetes |
| US7074788B2 (en) * | 2001-11-22 | 2006-07-11 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| BR0311952A (pt) | 2002-06-20 | 2005-04-19 | Biovitrum Ab | Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do snc |
| JP4754821B2 (ja) * | 2002-06-20 | 2011-08-24 | プロキシマゲン・リミテッド | 肥満症、ｉｉ型糖尿病およびｃｎｓ障害の治療に有用な新規化合物 |
| SE0303480D0 (sv) * | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
-
2006
- 2006-06-05 US US11/447,524 patent/US7582767B2/en not_active Expired - Fee Related
- 2006-06-15 EP EP06763743A patent/EP1896460B1/en not_active Not-in-force
- 2006-06-15 WO PCT/EP2006/063249 patent/WO2006134150A1/en active Application Filing
- 2006-06-15 KR KR1020087001242A patent/KR20080017482A/ko not_active Application Discontinuation
- 2006-06-15 ZA ZA200710468A patent/ZA200710468B/xx unknown
- 2006-06-15 CN CN2006800201432A patent/CN101193885B/zh not_active Expired - Fee Related
- 2006-06-15 ES ES06763743T patent/ES2330145T3/es active Active
- 2006-06-15 BR BRPI0612746-0A patent/BRPI0612746A2/pt not_active IP Right Cessation
- 2006-06-15 DK DK06763743T patent/DK1896460T3/da active
- 2006-06-15 CA CA002610383A patent/CA2610383A1/en not_active Abandoned
- 2006-06-15 JP JP2008516325A patent/JP2008543813A/ja not_active Withdrawn
- 2006-06-15 DE DE602006008002T patent/DE602006008002D1/de active Active
- 2006-06-15 EA EA200800071A patent/EA015671B1/ru not_active IP Right Cessation
- 2006-06-15 NZ NZ563510A patent/NZ563510A/en not_active IP Right Cessation
- 2006-06-15 AU AU2006259082A patent/AU2006259082B2/en not_active Ceased
- 2006-06-15 MX MX2007015988A patent/MX2007015988A/es active IP Right Grant
-
2007
- 2007-11-22 IL IL187575A patent/IL187575A/en not_active IP Right Cessation
-
2008
- 2008-01-17 NO NO20080354A patent/NO20080354L/no not_active Application Discontinuation
- 2008-07-28 HK HK08108312.6A patent/HK1112918A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL187575A0 (en) | 2008-03-20 |
| IL187575A (en) | 2012-12-31 |
| JP2008543813A (ja) | 2008-12-04 |
| CN101193885B (zh) | 2011-07-27 |
| HK1112918A1 (en) | 2008-09-19 |
| ES2330145T3 (es) | 2009-12-04 |
| BRPI0612746A2 (pt) | 2010-11-30 |
| EP1896460B1 (en) | 2009-07-22 |
| NZ563510A (en) | 2011-01-28 |
| US20060293361A1 (en) | 2006-12-28 |
| WO2006134150A1 (en) | 2006-12-21 |
| CA2610383A1 (en) | 2006-12-21 |
| EA200800071A1 (ru) | 2008-10-30 |
| DE602006008002D1 (de) | 2009-09-03 |
| AU2006259082A1 (en) | 2006-12-21 |
| CN101193885A (zh) | 2008-06-04 |
| AU2006259082B2 (en) | 2011-07-14 |
| EP1896460A1 (en) | 2008-03-12 |
| ZA200710468B (en) | 2009-04-29 |
| MX2007015988A (es) | 2008-03-07 |
| NO20080354L (no) | 2008-01-17 |
| EA015671B1 (ru) | 2011-10-31 |
| KR20080017482A (ko) | 2008-02-26 |
| US7582767B2 (en) | 2009-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1863474T3 (da) | Hidtil ukendte thiophenderivater som sphingosin-1-phosphat-1-receptoragonister | |
| DK1789041T3 (da) | Aryl-pyridinderivater som 11-beta-HSD1-inhibitorer | |
| DK1926722T3 (da) | Substituerede benzimidazoler som kinaseinhibitorer | |
| DK1797042T3 (da) | Indozolonderivater som 11B-HSD1-inhibitorer | |
| DK1856110T3 (da) | Oxyindol derivater som 5HT4-receptor agonister | |
| DK1863818T3 (da) | Acetylenyl-pyrazolo-pyrimidinderivater som mglur2-antagonister | |
| DK1846394T3 (da) | Pyrazolylaminopyridinderivater, der er egnede som kinaseinhibitorer | |
| DK1959951T3 (da) | Heteroaryl-substituerede piperidinderivater som L-CPT1-inhibitorer | |
| DK2094263T3 (da) | 2-adamantyl-butyramidderivater som selektive 11 beta-hsd1-inhibitorer | |
| DK2069310T3 (da) | Sulfonylpyrazolin-1-carboxamidin-derivater som 5-HT6-antagonister | |
| DK2091949T3 (da) | Indolderivater som S1P1-receptor agonister | |
| DK2086939T3 (da) | Pyridiacarboxamid som II-beta-HSDI-inhibitorer | |
| DK2004654T3 (da) | Pyrazolopyrimidin derivater til anvendelse som kinase antagonister | |
| ATE475662T1 (de) | Dihydropyrazolopyrimidinonderivate | |
| DK2078001T3 (da) | Diazepan-acetamidderivater som selektive 11-HSD1-inhibitorer | |
| ATE483711T1 (de) | Spiroindolinonderivate | |
| NO20082514L (no) | Aminopyrimidiner anvendelige som kinaseinhibitorer | |
| DK2220070T3 (da) | 2-benzylpyridazinonderivater som Met-kinaseinhibitorer | |
| DK1763517T3 (da) | Pyrimidinderivater som 11beta-HSD1-inhibitorer | |
| ATE469905T1 (de) | Pyridopyrimidinonderivate | |
| ATE512135T1 (de) | Spiroindolinonderivate | |
| DK1740569T3 (da) | Imidazol-derivater som TAFla-inhibitorer | |
| DK2035394T3 (da) | 2-pyrazincarboxamidderivater | |
| BRPI0714764A2 (pt) | Derivados substituídos de sulfonamida | |
| DK1904477T3 (da) | Indol-3-carbonyl-spiro-piperodom-derivater som V1A-receptorantagonister |